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Scarred liver tissue creates fertile ground for cancer development

Over 80% of hepatocellular carcinoma (HCC) – the third-leading cause of cancer deaths globally – emerges from advanced liver fibrosis or cirrhosis. A comprehensive review in Hepatology International synthesizes decades of research to reveal how scarred liver tissue becomes a breeding ground for cancer.

31 Jul 2025

Metformin lowers blood sugar by acting on brain pathways

Although metformin has been the go-to medication to manage type 2 diabetes for more than 60 years, researchers still do not have a complete picture of how it works.

31 Jul 2025

Black Death victims offer clues to childhood malnutrition and adult disease

The Black Death arrived on the shores of England in May 1348 and, in less than two years, spread throughout the country, killing an estimated 2 million people.

31 Jul 2025

Promising treatment slows liver cancer by inhibiting fat enzyme

Liver cancer cells thrive on fat, posing a serious risk of cancer diagnosis for millions of people living with fatty liver disease.

31 Jul 2025

Chronically ill? In Kennedy’s view, it might be your own fault

On a recent weekday evening, Ashly Richards helped her 13-year-old son, Case, with homework. He did math problems and some reading, underscoring how much he's accomplished at his school for children with autism.

31 Jul 2025

Promega Plasmid Collection, available through Addgene, equips industry and academic researchers with powerful bioluminescent assays that provide deeper insights into endogenous cellular biology

Addgene, a purpose-driven organization helping scientists conduct experiments with greater ease, speed, and reproducibility, today announced a strategic partnership with Promega to expand Addgene’s vast plasmid repository with the launch of the Promega Plasmid Collection.

From Promega Corporation 31 Jul 2025

Can stacking creatine and β-alanine give you extra gains? Here’s what science says

Co-supplementation with creatine and β-alanine may enhance high-intensity exercise performance, especially in repeated short bursts. However, it offers no additional benefit over creatine alone for maximal strength, aerobic capacity, or body composition.

30 Jul 2025

Why Spirulina could be a helpful natural option for lowering blood pressure

A comprehensive meta-analysis found that consuming whole microalgae, especially Spirulina, can significantly lower blood pressure, particularly in adults with elevated levels. No significant effects were observed for macroalgae or algae extracts.

30 Jul 2025

Brisk walking for just 15 minutes a day cuts death risk in low-income adults, study shows

Fast walking for as little as 15 minutes per day was linked to a nearly 20% reduction in mortality among predominantly Black and low-income American adults. Slow walking showed minimal benefit, but prolonged slow walking reduced the risk of death from ischemic heart disease.

30 Jul 2025

E-scooter riders are three times more likely than cyclists to end up in hospital, study shows

Stand-up electric scooter riders in Helsinki are over three times more likely than cyclists to sustain injuries requiring emergency care, with head trauma and alcohol use significantly more common in scooter crashes. Helmet use among scooter riders remains exceptionally low.

30 Jul 2025

Physicians lead effort to end race-based bias in lung function testing

Last July, a team of physicians and researchers successfully proposed modifications to the American Medical Association (AMA) Guides to the Evaluation of Permanent Impairment, advocating against the use of race in lung function testing.

30 Jul 2025

Immunocompromised people are susceptible to skin cancer caused directly by beta-HPV

Researchers at the National Institutes of Health (NIH) have shown for the first time that a type of human papillomavirus (HPV) commonly found on the skin can directly cause a form of skin cancer called cutaneous squamous cell carcinoma (cSCC) when certain immune cells malfunction.

30 Jul 2025

CPADS enables comprehensive analysis of drug resistance across 44 cancer types

CPADS integrates data from the Gene Expression Omnibus (GEO), The Cancer Genome Atlas (TCGA), and the Genomics of Drug Sensitivity in Cancer (GDSC) databases, encompassing over 29,000 samples across 44 cancer types and involving 288 drugs. It provides five main analysis modules: differential expression analysis, correlation analysis, pathway analysis, drug analysis, and gene perturbation analysis.

30 Jul 2025

Several healthy eating patterns may reduce the risk of type 2 diabetes across diverse ethnic groups

A large new meta-analysis of more than 800,000 participants to be presented at this year's Annual Meeting of the European Association for the Study of Diabetes (EASD) in Vienna, Austria (15-19 September) shows that high adherence to three well-established healthy eating patterns is linked to a lower risk of type 2 diabetes, regardless of one's ethnicity.

30 Jul 2025

Infant brain activity shows faster maturation after general anesthesia

New research published today in Proceedings of the National Academy of Sciences (PNAS) finds that prolonged and/or repeated exposure to gamma-aminobutyric acid (GABA) anesthetic agents (sevoflurane, propofol) for infants in the first two months of life resulted in an accelerated maturation of brain electrical activity patterns evoked by visual stimuli when recorded at 2-5 months of age, compared to infants who did not have early general anesthesia exposure.

30 Jul 2025

Machine learning model predicts radiotherapy response in patients with nasopharyngeal carcinoma

Researchers in China have developed a powerful machine learning model that can help determine which patients with nasopharyngeal carcinoma (NPC) are likely to respond well to radiotherapy-a common treatment for this type of cancer.

30 Jul 2025

Experimental drug found to be safe and effective in treating children with MIS-C

In a small trial, Mass General Brigham researchers found a drug designed to treat Celiac disease supported a more rapid return to normal activities for patients following COVID.

30 Jul 2025

Low FODMAP diet found to repair leaky gut in IBS-D patients

In a study, patients with irritable bowel syndrome with diarrhea, or IBS-D, who went on a low FODMAP diet saw an improvement of colonic barrier dysfunction, commonly known as "leaky gut."

30 Jul 2025

Thalamic feedback pathway found to tune sensory perception

The cerebral cortex processes sensory information via a complex network of neural connections. How are these signals modulated to refine perception? A team from the University of Geneva (UNIGE) has identified a mechanism by which certain thalamic projections target neurons and modify their excitability.

30 Jul 2025

Respiratory infections can reactivate dormant breast cancer cells

Researchers at the University of Colorado Anschutz Medical Campus, Montefiore Einstein Comprehensive Cancer Center (MECCC), and Utrecht University have found the first direct evidence that common respiratory infections, including COVID-19 and influenza, can awaken dormant breast cancer cells that have spread to the lungs, setting the stage for new metastatic tumors.

30 Jul 2025

Research News and Research

Scarred liver tissue creates fertile ground for cancer development

Metformin lowers blood sugar by acting on brain pathways

Black Death victims offer clues to childhood malnutrition and adult disease

Promising treatment slows liver cancer by inhibiting fat enzyme

Chronically ill? In Kennedy’s view, it might be your own fault

Promega Plasmid Collection, available through Addgene, equips industry and academic researchers with powerful bioluminescent assays that provide deeper insights into endogenous cellular biology

Can stacking creatine and β-alanine give you extra gains? Here’s what science says

Why Spirulina could be a helpful natural option for lowering blood pressure

Brisk walking for just 15 minutes a day cuts death risk in low-income adults, study shows

E-scooter riders are three times more likely than cyclists to end up in hospital, study shows

Physicians lead effort to end race-based bias in lung function testing

Immunocompromised people are susceptible to skin cancer caused directly by beta-HPV

CPADS enables comprehensive analysis of drug resistance across 44 cancer types

Several healthy eating patterns may reduce the risk of type 2 diabetes across diverse ethnic groups

Infant brain activity shows faster maturation after general anesthesia

Machine learning model predicts radiotherapy response in patients with nasopharyngeal carcinoma

Experimental drug found to be safe and effective in treating children with MIS-C

Low FODMAP diet found to repair leaky gut in IBS-D patients

Thalamic feedback pathway found to tune sensory perception

Respiratory infections can reactivate dormant breast cancer cells

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