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Innovative nanoparticle breaks blood-brain barrier to target breast cancer and brain metastases

Researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine have developed a nanoparticle that can penetrate the blood-brain barrier.

6 May 2024

Scientists employ geology tool to detect atomic fingerprints of cancer

Scientists at the University of Colorado Boulder and Princeton University have, for the first time, employed a tool often used in geology to detect the atomic fingerprints of cancer.

6 May 2024

Researchers identify novel biomarkers in renal cell carcinomas

A new study led by University of Michigan Health Rogel Cancer Center researchers identifies novel biomarkers in renal cell carcinomas.

6 May 2024

Breakthrough imaging technique enhances evaluation of cardiac conditions and chest pain

A new imaging technique tested in patients could improve the evaluation of cardiac conditions and undiagnosed chest pain.

6 May 2024

Multifunctional Ablative Gastrointestinal Imaging Capsule: A game-changer in esophagus surveillance and interventions

In a groundbreaking advancement in gastrointestinal health, researchers from Johns Hopkins University have developed the Multifunctional Ablative Gastrointestinal Imaging Capsule (MAGIC) – a game-changer in esophagus surveillance and interventions.

6 May 2024

CRISPR-based gene editing shows promise in treating rare form of blindness

About 79% of clinical trial participants experienced measurable improvement after receiving experimental, CRISPR-based gene editing that is designed to fix a rare form of blindness, according to a paper published in the New England Journal of Medicine.

6 May 2024

UC San Diego's open source AI platform revolutionizes multi-target drug discovery

Scientists at UC San Diego have developed a machine learning algorithm to simulate the time-consuming chemistry involved in the earliest phases of drug discovery, which could significantly streamline the process and open doors for never-before-seen treatments.

6 May 2024

CRISPR gene editing shows promise for treating individuals with a form of inherited blindness

Results from a groundbreaking clinical trial of CRISPR gene editing in 14 individuals with a form of inherited blindness show that the treatment is safe and led to measurable improvements in 11 of the participants treated.

6 May 2024

Plant-based medication may be an effective therapy to help people quit vaping

Eleven million U.S. adults use e-cigarettes to vape nicotine, and about half of them say that they want to stop, but many have trouble doing so because nicotine is an addictive drug.

6 May 2024

Study identifies APOE4 homozygotes as high-risk group for Alzheimer's disease

Researchers from the Research Area on Neurological Diseases, Neuroscience, and Mental Health at the Sant Pau Research Institute, led by Dr. Juan Fortea, Director of the Memory Unit of the Neurology Service at the same hospital, have found that over 95% of individuals over 65 years old who have two copies of the APOE4 gene -APOE4 homozygotes- show biological characteristics of Alzheimer's pathology in the brain or biomarkers of this disease in cerebrospinal fluid and PET scans.

6 May 2024

Personalized screening approach may better predict preeclampsia in the first trimester of pregnancy

A new screening algorithm for preeclampsia combining maternal history, ultrasound data and several tests for blood markers may better predict the majority of preeclampsia cases in the first trimester of pregnancy, when it may still be preventable, according to new research published today in Hypertension, an American Heart Association journal.

6 May 2024

Durable lymph-node expansion improves vaccine responses against tumors

Each one of us has around 600 lymph nodes (LNs) – small, bean-shaped organs that house various types of blood cells and filter lymph fluid – scattered throughout our bodies.

6 May 2024

Stranded in the ER, seniors await hospital care and suffer avoidable harm

Every day, the scene plays out in hospitals across America: Older men and women lie on gurneys in emergency room corridors moaning or suffering silently as harried medical staff attend to crises.

6 May 2024

Could better inhalers help patients, and the planet?

Miguel Divo, a lung specialist at Brigham and Women's Hospital in Boston, sits in an exam room across from Joel Rubinstein, who has asthma. Rubinstein, a retired psychiatrist, is about to get a checkup and hear a surprising pitch — for the planet, as well as his health.

6 May 2024

Can monitoring and encouraging physical activity through phone-based apps improve glycemic control and weight loss in type 2 diabetes patients?

Whether a smartphone application (app) for maintaining personal health records encouraged physical activity, improved step counts, and glycemic control.

6 May 2024

WHI reports key findings on postmenopausal women’s health

Researchers from the Brigham and colleagues report on the long-term follow-up of the largest study of women’s health in the U.S., shedding light on the role of menopausal hormone therapy, calcium and vitamin D supplementation, and a low-fat dietary pattern among postmenopausal women

6 May 2024

Genomics plc and GSK collaborate to harness polygenic risk scores in clinical trials

Genomics plc and GSK announced a new collaboration to explore the potential for using polygenic risk scores (PRS) in clinical trials, to improve understanding of disease risk and patient selection, which could support optimization of trial design.

6 May 2024

Janssen-Cilag seeks European approval for guselkumab in ulcerative colitis and Crohn’s disease treatment

Janssen-Cilag International NV, a Johnson & Johnson company, today announced it has submitted applications to the European Medicines Agency (EMA) seeking to expand the Marketing Authorization Application for TREMFYA® (guselkumab) to include the treatment of adult patients with moderately to severely active ulcerative colitis and moderately to severely active Crohn’s disease.

6 May 2024

Modified sugar molecules boost stem cell therapy for brain repair after cardiac arrest

Researchers at the University of Maryland School of Medicine (UMSOM) have identified an innovation in stem cell therapy to regenerate neural cells in the brain after cardiac arrest in an animal model.

6 May 2024

Evaluating ChatGPT for structured data extraction from clinical notes

Researchers evaluate the ability of ChatGPT to extract structured data from unstructured clinical notes.

5 May 2024

Medicine News and Research

Innovative nanoparticle breaks blood-brain barrier to target breast cancer and brain metastases

Scientists employ geology tool to detect atomic fingerprints of cancer

Researchers identify novel biomarkers in renal cell carcinomas

Breakthrough imaging technique enhances evaluation of cardiac conditions and chest pain

Multifunctional Ablative Gastrointestinal Imaging Capsule: A game-changer in esophagus surveillance and interventions

CRISPR-based gene editing shows promise in treating rare form of blindness

UC San Diego's open source AI platform revolutionizes multi-target drug discovery

CRISPR gene editing shows promise for treating individuals with a form of inherited blindness

Plant-based medication may be an effective therapy to help people quit vaping

Study identifies APOE4 homozygotes as high-risk group for Alzheimer's disease

Personalized screening approach may better predict preeclampsia in the first trimester of pregnancy

Durable lymph-node expansion improves vaccine responses against tumors

Stranded in the ER, seniors await hospital care and suffer avoidable harm

Could better inhalers help patients, and the planet?

Can monitoring and encouraging physical activity through phone-based apps improve glycemic control and weight loss in type 2 diabetes patients?

WHI reports key findings on postmenopausal women’s health

Genomics plc and GSK collaborate to harness polygenic risk scores in clinical trials

Janssen-Cilag seeks European approval for guselkumab in ulcerative colitis and Crohn’s disease treatment

Modified sugar molecules boost stem cell therapy for brain repair after cardiac arrest

Evaluating ChatGPT for structured data extraction from clinical notes

Everything there is to know about biosimilars eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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