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Cleveland Clinic team uncovers genetic link to osteosarcoma

Researchers at Cleveland Clinic Children's have helped identify a previously unknown gene that increases the risk of developing osteosarcoma, the most common type of malignant bone tumor in children and young adults.

9 Oct 2025

Breakthrough in cancer therapy targets key protein interaction to suppress tumors

Researchers at the Francis Crick Institute and Vividion Therapeutics have identified chemical compounds that can precisely block the interaction between the major cancer-driving gene RAS, and a key pathway for tumor growth.

9 Oct 2025

Nanoparticle vaccine shows promise in preventing multiple cancers in mice

A study led by University of Massachusetts Amherst researchers demonstrates that their nanoparticle-based vaccine can effectively prevent melanoma, pancreatic and triple-negative breast cancer in mice.

9 Oct 2025

Innovative system accurately detects genetic mutations in the brain tumor within 25 minutes

A research team in Japan has developed an innovative system that can accurately detect genetic mutations in the brain tumor within just 25 minutes.

9 Oct 2025

Engineered virus therapy triggers powerful immune responses in glioblastoma

A new study led by Break Through Cancer's Accelerating Glioblastoma (GBM) Therapies Through Serial Biopsies TeamLab has revealed that an engineered virus therapy, CAN-3110, triggered powerful immune responses deep inside glioblastoma tumors that were invisible to standard imaging like MRI, according to early analyses of two patients with recurrent GBM.

9 Oct 2025

Changes in the gastric microbiota linked to growth of neuroendocrine tumors

Researchers from Osaka Metropolitan University have discovered how the balance of bacteria in the stomach affects the growth of neuroendocrine tumors (NETs).

8 Oct 2025

Newly identified protein acts as a traffic controller for DNA replication

Mayo Clinic researchers have identified a protein that acts like a traffic controller for DNA, preventing damage during cell division - a discovery that could lead to new cancer therapies, according to a study published in Nature.

8 Oct 2025

UCSF team uncovers breakthrough immunotherapy for colon cancer liver metastases

Advanced colon cancer is the leading cause of cancer-related death in young American men and the second highest worldwide. In the majority of these patients, as the cancer advances it metastasizes to the liver.

8 Oct 2025

Repeated sampling offers insight into glioblastoma therapy response

A multi-institutional study from the Accelerating GBM Therapies Through Serial Biopsies TeamLab, led by investigators from the Mass General Brigham Cancer Institute, found that serially testing tumor samples can help detect when a cancer treatment is activating the immune system in recurrent glioblastoma (GBM), even when traditional imaging measures cannot.

8 Oct 2025

Nanomedicine emerges as a key tool to boost cancer immunotherapy

Scientists at the Fralin Biomedical Research Institute at VTC and their collaborators are exploring emerging trends in cancer immunotherapy, with back-to-back review articles published in Nature Cancer and Trends in Cancer that look at how nanotechnology could reprogram the immune system and help overcome tumors' defenses.

8 Oct 2025

Engineered Salmonella therapy delivers immune payloads to combat cancer

A new research paper was published in Volume 16 of Oncotarget on October 6, 2025, titled "ACTM-838, a novel systemically delivered bacterial immunotherapy that enriches in solid tumors and delivers IL-15/IL-15Rα and STING payloads to engage innate and adaptive immunity in the TME and enable a durable anti-tumor immune response."

8 Oct 2025

Engineered CAR-NK cells show enhanced cancer killing and immune evasion

One of the newest weapons that scientists have developed against cancer is a type of engineered immune cell known as CAR-NK (natural killer) cells. Similar to CAR-T cells, these cells can be programmed to attack cancer cells.

8 Oct 2025

Next-generation imaging promises sharper, deeper view of living tissues

A University of Arizona research team will receive nearly $2.7 million from the NIH's Common Fund Venture Program to advance next-generation imaging technologies that allow deeper, clearer views inside the body without the need for invasive procedures.

7 Oct 2025

Unlocking the mysteries of treatment-resistant prostate cancer

Advances in prostate cancer early detection and treatment have improved outcomes in men diagnosed with the disease.

7 Oct 2025

New drug combination could delay the progression of advanced prostate cancer

A new drug combination could significantly delay the progression of a life-threatening form of prostate cancer in men with specific genetic mutations, finds a major international trial led by UCL researchers.

7 Oct 2025

IASLC proposes new tumor budding-based grading system for lung squamous cell carcinoma

Invasive lung squamous cell carcinoma (LUSC) accounts for approximately one-quarter of all lung cancers, but therapeutic options for LUSC remain limited, primarily due to the absence of well-defined, targetable molecular alterations.

6 Oct 2025

DKMS advances blood cancer research with groundbreaking ASAP study

The selection of patients for allo-HSCT and the best approach to bridging patients to transplantation is continuously discussed by experts.

6 Oct 2025

Moffitt awarded $22.4 million grant to lead novel studies and clinical trials for leptomeningeal disease

Researchers at Moffitt Cancer Center have been awarded a $22.4 million grant from the U.S. Department of War to lead groundbreaking studies and clinical trials for leptomeningeal disease, a devastating complication of breast and other cancers that spreads to the coverings of the brain and spinal cord.

6 Oct 2025

Inflammatory responses may play a role in cancer-related fatigue

New research reveals that inflammatory responses may play a role in different types of fatigue experienced by many people with cancer.

6 Oct 2025

Researchers identify a central controller of mitochondrial dynamics in disease

A key switch for cellular energy balance has been discovered in cells: it could potentially become the target of new therapies for diseases ranging from Parkinson's to rare disorders caused by defects in the cell's powerhouses, the mitochondria.

6 Oct 2025