Protein C News and Research

RSS

Camelid nanobody anti-SARS-CoV-2 drug candidates

In a research paper recently published in the journal eLife, researchers from several US institutions have developed a nanobody-based candidate drug that effectively prevents and suppresses severe SARS-CoV-2 infection in animals.

12 Aug 2021

Optical nanoscopy reveals how SARS-CoV-2 infection alters human airway cells

How do viruses reorganize host cells with spatial and molecular specificity? Researchers from the Netherlands provided new insights in a recent study posted to the bioRxiv* preprint server, where they use optical nanoscopy to look at severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-triggered changes in primary human airway cells.

12 Aug 2021

Researchers discover how PARP inhibitors selectively kill BRCA-mutant cancer cells

A team of Massachusetts General Hospital researchers has discovered how an important class of anti-cancer drugs called PARP inhibitors works, a finding that could help improve treatment and prolong survival for patients with breast cancer and other malignancies.

12 Aug 2021

Study finds four circulating miRNAs which could effectively inhibit SARS-CoV-2 replication

In a new study, Chen-Yu Zhang's group from Nanjing University presents a rather striking finding that four circulating miRNAs, which are high in healthy people and much lower in older people and diabetic patients, could effectively inhibit SARS-CoV-2 replication by directly targeting the S protein.

12 Aug 2021

Scientists find clues to how a specific synapse type regulates anxiety-like behavior

The mechanisms behind the organization of neuronal synapses remain unclear owing to the sheer number of genes, proteins, and neuron types involved.

12 Aug 2021

Immunotherapy pairs ultrasound with immune cells to destroy tumors without toxic side effects

Bioengineers at the University of California San Diego have developed a cancer immunotherapy that pairs ultrasound with cancer-killing immune cells to destroy malignant tumors while sparing normal tissue.

12 Aug 2021

Novel blood test as adjunct to MRI improves prostate cancer screening

Researchers at Karolinska Institutet in Sweden recently reported that magnetic resonance imaging (MRI) could reduce overdiagnoses and thereby improve prostate cancer screening.

12 Aug 2021

Researchers determine the structure of receptor involved in type 2 diabetes and other pathologies

Researchers from the University of Southern California, Merck & Co., Skoltech, MIPT, UCLA, and the Université de Sherbrooke have determined the structure of the human leukotriene B4 receptor 1, involved in inflammatory, infectious, allergic, and tumorigenic diseases.

12 Aug 2021

Targeting a skin protein may reduce the severity of psoriasis, study reveals

Results from a Michigan Medicine study reveal that targeting a protein found in the skin may reduce the severity of psoriasis.

12 Aug 2021

UC San Diego scientists develop new method to keep cultured cells healthy

Hematopoietic stem cells — the precursors to blood cells — have been notoriously difficult to grow in a dish, a critical tool in basic research.

12 Aug 2021

Skin cells could provide better understanding of molecular mechanisms of frontotemporal dementia

A new study from the University of Eastern Finland suggests that skin fibroblasts from frontotemporal dementia patients may be useful in investigating underlying disease mechanisms as well as in biomarker and drug research.

12 Aug 2021

South Australian-developed SARS-CoV-2 vaccine shows promise to prevent COVID-19 lung infection

A South Australian-developed SARS-CoV-19 vaccine is preparing to progress to the final stages of human clinical trials after early animal testing confirmed its safety and effectiveness in preventing COVID-19 lung infection.

12 Aug 2021

SARS-CoV-2 detection by machine learning surface-enhanced Raman spectroscopy

Surface-enhanced Raman spectroscopy is a highly sensitive molecule characterization method, significantly more sensitive than ordinary Raman spectroscopy due to the excitation of Raman modes matching the plasmon resonance frequency of the surface metal utilized, usually gold, silver, or copper.

11 Aug 2021

VPS29 gene facilitates coronavirus cell entry

In a research paper recently uploaded to the bioRxiv* preprint server by Poston et al. (August 8th, 2021), common host factors amongst several zoonotic pathogens are explored by CRISPR-Cas9 screening in human lung cells, focusing in particular on the betacoronavirus genus.

11 Aug 2021

New research offers hope to increase efficacy of immunotherapy for lung cancer

Lung cancer is the leading cause of cancer-related death. Current treatments employ immunotherapy, often in combination with chemotherapy, but benefits to patients remain slight.

11 Aug 2021

Evaluation of mRNA vaccine responses with a surrogate SARS-CoV-2 viral neutralization assay

In the current study, the authors evaluate several different competitive ELISAs that could be used to measure serum antibodies.

11 Aug 2021

Study uncovers molecular mechanisms that promote cell-to-cell adhesion and communication

A study led by Northwestern Medicine investigators has identified the molecular mechanisms within protein complexes that promote cell-to-cell adhesion and communication, according to findings published in the Proceedings of the National Academy of Sciences.

11 Aug 2021

Protein C News and Research

Camelid nanobody anti-SARS-CoV-2 drug candidates

Optical nanoscopy reveals how SARS-CoV-2 infection alters human airway cells

Researchers discover how PARP inhibitors selectively kill BRCA-mutant cancer cells

Study finds four circulating miRNAs which could effectively inhibit SARS-CoV-2 replication

Scientists find clues to how a specific synapse type regulates anxiety-like behavior

Immunotherapy pairs ultrasound with immune cells to destroy tumors without toxic side effects

Novel blood test as adjunct to MRI improves prostate cancer screening

Researchers determine the structure of receptor involved in type 2 diabetes and other pathologies

Targeting a skin protein may reduce the severity of psoriasis, study reveals

UC San Diego scientists develop new method to keep cultured cells healthy

Skin cells could provide better understanding of molecular mechanisms of frontotemporal dementia

South Australian-developed SARS-CoV-2 vaccine shows promise to prevent COVID-19 lung infection

SARS-CoV-2 detection by machine learning surface-enhanced Raman spectroscopy

VPS29 gene facilitates coronavirus cell entry

New research offers hope to increase efficacy of immunotherapy for lung cancer

Evaluation of mRNA vaccine responses with a surrogate SARS-CoV-2 viral neutralization assay

Study uncovers molecular mechanisms that promote cell-to-cell adhesion and communication

COVID-19 vaccine likely protects people living with HIV, study shows

Small NIH clinical trial shows that new monoclonal antibody can prevent malaria

Scientists develop new approach to identify proteins in the living brain

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Latest News