Antigen News and Research

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Researchers explore potential new target for cancer immunotherapy

A new study posted to the bioRxiv* preprint server, focused on the role of YAP in regulating MHC-I APM expression within tumor cells.

27 Feb 2023

Does a negative COVID-19 test before air travel reduce the spread of COVID-19 transmission during and after travel?

Researchers assessed the impact of pre-departure testing on SARS-CoV-2-positivity rates post-arrival among international travelers.

27 Feb 2023

Study supports the concept of atherosclerosis as a T-cell autoimmune disease targeting the arterial wall

Researchers assessed T-cell tolerance checkpoints observed in atherosclerosis.

27 Feb 2023

High-dose ivermectin does not reduce COVID-19 symptom duration among mild-to-moderate outpatients

Researchers evaluate the efficacy of ivermectin in a maximum dosage of 600 μg/kg/day over six days in treating early mild-to-moderate COVID-19.

27 Feb 2023

Study shows COVID-19 rates were likely forty-times higher than CDC estimates during BA.4/BA.5 dominant period in the U.S.

Researchers evaluate the prevalence of SARS-CoV-2 infections and the incidence of long COVID during BA.4/BA.5 dominant period.

27 Feb 2023

Study findings likely to guide the design of engineered TAPBPR variants with tailored HLA specificity

Researchers at Children's Hospital of Philadelphia (CHOP) have identified variants of a chaperone molecule that optimizes the binding and presentation of foreign antigens across the human population, which could open the door to numerous applications where robust presentation to the immune system is important, including cell therapy and immunization. The findings were published today in Science Advances.

24 Feb 2023

University of Vermont Cancer Center to offer a novel, highly effective form of cancer treatment

The University of Vermont Cancer Center will offer a novel, highly effective form of cancer treatment called CAR T-cell therapy beginning in February, when final accreditation and approval to begin treating patients is expected.

24 Feb 2023

Clec9A-RBD immunization could trigger robust and sustained systemic and mucosal immune responses against rapidly evolving SARS-CoV-2 variants

Researchers assessed the impact of a single-dose dendritic cell vaccine candidate on immune responses against SARS-CoV-2.

23 Feb 2023

Study shows antibody-dependent SARS-CoV-2 transmission and pathogenesis

Researchers reported that some monoclonal nAbs directed against distinct RBD epitopes nested inside the SARS-CoV-2 S could substitute ACE2 as a receptor and support fusion between viral and host cell membranes facilitating viral infectivity.

23 Feb 2023

Long-awaited findings from the IMMUNEBRIDGE study reveal gaps in SARS-CoV-2 immunity

Moderate to high protection was observed against severe COVID-19 in most age groups, while low protection was observed against infection for all ages.

22 Feb 2023

Researchers estimate the environmental impacts of prostate MRI and biopsy

A Yale-led study examines the potential environmental benefits of more carefully selecting patients for prostate biopsy in a way that can also spare low-yield and potentially harmful procedures.

22 Feb 2023

RBD-NTD-subunit protein vaccine provides a promising booster vaccination strategy capable of protecting against known SARS-CoV-2 variants

Researchers assessed the impact of SARS-CoV-2 spike NTD incorporation into the RBD protein vaccine.

22 Feb 2023

Prior COVID highly protective against severe disease ten months post-infection

In a recent study published in the Lancet, researchers performed a systematic review of scientific literature published from inception up to September 31, 2022, that documented the reduction in risk of coronavirus disease 2019 (COVID-19) among individuals with a prior severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection vis-à-vis those with no COVID-19 history.

19 Feb 2023

How effective has the bivalent booster COVID vaccination been?

In a recent study published in the journal Eurosurveillance, researchers estimated the effectiveness of bivalent messenger ribonucleic acid (mRNA) vaccines targeting the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BA.1 subvariant and the original Wuhan-Hu1 strain against Omicron infections in the vaccinated population of the Netherlands between 26 September and 19 December 2022.

19 Feb 2023

Epidemic dynamics of the SARS-CoV-2 Omicron variant in China during the transition from 'zero-COVID' to little-to-no intervention efforts

Researchers quantified the magnitude and rate of the SARS-CoV-2 Omicron variant outbreak in China following the abrupt exit from the ‘zero-COVID’ guidelines.

17 Feb 2023

Omicron has higher risk of in-hospital mortality compared to influenza

In a recent study published in the journal JAMA Network Open, researchers compared the hospital outcomes of patients infected with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant with those of influenza patients in Switzerland, assess the current disease burden due to coronavirus disease 2019 (COVID-19).

16 Feb 2023

Long-COVID associated with a greater likelihood of unemployment

In a recent study published in the journal JAMA Network Open, researchers assessed the unemployment rates among individuals who developed post–coronavirus disease 2019 (COVID-19) condition (PCC) or long COVID after an acute severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection to determine the functional and neurocognitive impairment levels associated with long COVID.

16 Feb 2023

Antigen News and Research

Researchers explore potential new target for cancer immunotherapy

Does a negative COVID-19 test before air travel reduce the spread of COVID-19 transmission during and after travel?

Study supports the concept of atherosclerosis as a T-cell autoimmune disease targeting the arterial wall

High-dose ivermectin does not reduce COVID-19 symptom duration among mild-to-moderate outpatients

Study shows COVID-19 rates were likely forty-times higher than CDC estimates during BA.4/BA.5 dominant period in the U.S.

Study findings likely to guide the design of engineered TAPBPR variants with tailored HLA specificity

University of Vermont Cancer Center to offer a novel, highly effective form of cancer treatment

Clec9A-RBD immunization could trigger robust and sustained systemic and mucosal immune responses against rapidly evolving SARS-CoV-2 variants

Study shows antibody-dependent SARS-CoV-2 transmission and pathogenesis

Long-awaited findings from the IMMUNEBRIDGE study reveal gaps in SARS-CoV-2 immunity

Researchers estimate the environmental impacts of prostate MRI and biopsy

RBD-NTD-subunit protein vaccine provides a promising booster vaccination strategy capable of protecting against known SARS-CoV-2 variants

Prior COVID highly protective against severe disease ten months post-infection

How effective has the bivalent booster COVID vaccination been?

Epidemic dynamics of the SARS-CoV-2 Omicron variant in China during the transition from 'zero-COVID' to little-to-no intervention efforts

Omicron has higher risk of in-hospital mortality compared to influenza

Long-COVID associated with a greater likelihood of unemployment

After recovering from mild to moderate COVID-19, asthma control deteriorates

Genetic features of the immune system linked to a person's ability to resist new COVID-19 variants

Study highlights the interconnectedness of autoimmunity and cancer

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