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TRPM1 loss drives rhythmic activity across retinal diseases

Rhythmic electrical activity in the retina (known as pathological oscillations) has been observed in several eye diseases, including congenital stationary night blindness (CSNB) and retinitis pigmentosa (RP).

18 Nov 2025

Toward precision diagnosis and treatment of radiation-induced brain injury

Radiation-induced brain injury (RIBI) is a serious and often delayed complication of cranial radiotherapy, which remains a cornerstone in the treatment of brain tumors such as gliomas, metastases, and lymphomas.

18 Nov 2025

Researchers identify key differences between two subtypes of chronic lymphocytic leukemia

Researchers at the University of Eastern Finland and their international collaborators have identified key developmental and molecular differences between the two main subtypes of chronic lymphocytic leukemia, CLL.

18 Nov 2025

Researchers develop novel computational method to interpret complex single-cell data

Researchers from Turku Bioscience Centre at the University of Turku, Finland, have developed a new computational method to interpret complex single-cell data. The method helps researchers identify and group cell types across samples.

17 Nov 2025

First-of-its-kind provincial registry opens to build Ontario’s hereditary cancer database

The Ontario Hereditary Cancer Research Network's (OHCRN) participant portal is now open and Ontarians at risk of hereditary cancers are invited to register.

17 Nov 2025

Breast cancer cells use a molecular switch to survive stress

Cells are regularly faced with environmental stresses that may damage or destroy them. To survive, they quickly adjust their gene expression to protect themselves.

17 Nov 2025

Schizophrenia risk detectable at birth through epigenetic signatures

Genetic susceptibility to neurodevelopmental conditions such as schizophrenia, autism, and ADHD can be linked, in part, to distinct epigenetic signatures in newborn cord blood.

17 Nov 2025

Why early- and late-onset depression are fundamentally different

Genetic differences in early- and late-onset depression highlight distinct risk profiles, informing targeted strategies for improved clinical outcomes.

17 Nov 2025

New method enables construction of complete mycobacteriophage genomes

A team co-led by University of Pittsburgh’s Graham Hatfull has developed a method to construct bacteriophages with entirely synthetic genetic material, allowing researchers to add and subtract genes at will.

17 Nov 2025

Study finds increased rates of DNA mutations in mice pups conceived with IVF

Mice pups conceived with in vitro fertilization (IVF) in the lab have slightly increased rates of DNA errors, or mutations, compared to pups conceived naturally, a new study on artificial reproductive technologies suggests.

17 Nov 2025

Parental postpartum depression linked to higher autism risk

Findings reveal a strong link between parental postpartum depression and autism risk, stressing the importance of mental health support for new parents.

17 Nov 2025

Subtle changes in the composition of short tandem repeats may shape disease risk

Scientists at The Hospital for Sick Children (SickKids) have revealed a previously overlooked layer of genetic variation that could help explain why people experience disease differently, and why some treatments work better for certain populations.

14 Nov 2025

Uncovering hidden causes of recurrent pregnancy loss with optical genome mapping

Pregnancy loss may occur in as many as 25% of all pregnancies. Most of these losses occur in the first trimester, and about half are caused by genetic or chromosomal issues.

14 Nov 2025

Understanding leptin's dual function in MAFLD pathogenesis

Metabolic dysfunction-associated fatty liver disease (MAFLD) has emerged as a predominant chronic liver condition globally, intricately linked with obesity, type 2 diabetes (T2DM), and metabolic syndrome.

14 Nov 2025

Hypertension may induce early gene expression changes in brain cells

Hypertension impairs blood vessels, neurons and white matter in the brain well before the condition causes a measurable rise in blood pressure, according to a new preclinical study from Weill Cornell Medicine investigators.

14 Nov 2025

Exploring m6A RNA modification as a therapeutic target in cardiovascular disorders

Emerging research highlights the transformative potential of m6A RNA modification in the diagnosis and treatment of cardiovascular diseases (CVDs).

14 Nov 2025

Transforming colorectal cancer research with patient-derived xenograft models

Patient-derived xenograft (PDX) models are emerging as a transformative tool in colorectal cancer (CRC) research, offering unparalleled insights into tumor biology, drug resistance, and personalized treatment approaches.

14 Nov 2025

Study unites global neuroscientists to share brain data

Imagine if every neuroscientist in the world could suddenly speak the same language and share their discoveries instantly. Allen Institute researchers and engineers have now unlocked that potential and the vast discoveries it could lead to through the new Brain Knowledge Platform (BKP).

14 Nov 2025

Tiny antibiotic traces found to greatly accelerate resistance spread

Antibiotic resistance is widely recognized as one of the most urgent public health challenges of the twenty first century.

13 Nov 2025

Scientists map the genetic control system behind FOXP3 in immune cells

The immune system faces a delicate balancing act: it must be aggressive enough to fight infections and cancer, yet restrained enough to avoid attacking the body's own tissues.

13 Nov 2025