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Antibiotic rifampicin attenuates C9orf72-linked dementia in genetically modified mice

What did Stephen Hawking and Mao Zedong have in common? They both suffered from Amyotrophic Lateral Sclerosis (ALS), a cure for which remains elusive. Scientists from Osaka Metropolitan University took an important step toward prevention of ALS and another brain disorder called Frontotemporal dementia (FTD) with their research on the effects of the antibiotic rifampicin on genetically modified mice.

23 May 2022

Pioneering study could transform the treatment landscape for babies with infantile spasms

Infantile spasm (IS) is a severe epileptic syndrome of infancy and accounts for 50% of all epilepsy cases that occur in babies during the first year of life.

20 May 2022

Researchers analyze the development and genetic profile of brain's immune cells

Thanks to over a century of modern neuroscience, we have made significant strides in our understanding of the brain. Nonetheless, we have only just begun to scratch the surface of how this amazingly complex organ works.

20 May 2022

Mice study links dietary cholesterol with exacerbation of influenza

New research from the University of Illinois suggests high levels of dietary cholesterol make mice sicker when infected with influenza. The study is the first to link cholesterol in the diet with exacerbation of a viral infection.

19 May 2022

Epilepsy drug inhibits the growth of NF1 tumors in mice

People with neurofibromatosis type 1 (NF1) develop tumors on nerves throughout their bodies. These tumors are usually benign - meaning they don't spread to other parts of the body and are not considered life-threatening - but they can still cause serious medical problems such as blindness, especially when they form in the brain and nerves.

19 May 2022

Study supports the use of age-specific risk prediction scores for dementia

Which vascular risk factors are associated with the risk of developing dementia may vary with age. A new study shows that among people around age 55, the risk of developing dementia over the next 10 years was increased in those with diabetes and high blood pressure.

19 May 2022

Experimental drug more effective than existing FDA-approved medications for ALS

New research on the experimental drug, NU-9, invented and developed by two Northwestern University scientists to treat ALS (amyotrophic lateral sclerosis), shows it is more effective than existing FDA-approved drugs for the disease.

17 May 2022

Exposure to cold and warm temperatures causes changes in gene expression in various organs

Human beings, like most organisms, are constantly exposed to alternating colder or warmer temperatures.

17 May 2022

Study shows how MS patients treated with Rituximab react to COVID-19 vaccination

MS patients treated with Rituximab have better responses to the COVID-19 vaccine if they have higher B cell counts.

12 May 2022

The promise of RNA medicine is targeted and personalized

The development of messenger RNA (mRNA) vaccines against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has only increased the impetus in this field.

11 May 2022

Maternal antidepressant use during pregnancy does not increase epilepsy risk in babies

A new study suggests that antidepressant use by mothers during the first trimester of pregnancy does not increase the chances of epilepsy and seizures in babies.

11 May 2022

Rutgers study identifies key protein for brain stem cell longevity

A receptor that was first identified as necessary for insulin action, that also is located on the neural stem cells found deep in the brains of mice, is pivotal for brain stem cell longevity, according to a Rutgers study, a finding that has important implications for brain health and future therapies for brain disorders.

11 May 2022

New methods can make spinal cord less excitable and could be used to treat muscle spasms

Poor sleep, difficulty moving and injuries from hitting something accidentally are just some of the challenges faced by suffers of often-painful involuntary muscle spasms.

11 May 2022

Report highlights the need for an office to support autoimmune disease research across NIH institutes

While the quantity and quality of research that the National Institutes of Health (NIH) conducts on autoimmune diseases is impressive, a strategic plan and a well-funded office to support the coordination of all autoimmune disease research across NIH institutes and centers are needed, says a new congressionally mandated report from the National Academies of Sciences, Engineering, and Medicine.

10 May 2022

Detecting treatments for autoimmune disease using an immune ‘fingerprint’

In this interview, we speak to Professor Joseph Powell about his latest research that investigated the use of immune 'fingerprints' to treat autoimmune disease.

10 May 2022

NIH launches clinical study to evaluate an investigational preventative vaccine for Epstein-Barr virus

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, has launched an early-stage clinical trial to evaluate an investigational preventative vaccine for Epstein-Barr virus (EBV).

6 May 2022

Viral microRNA acts as a master regulator to induce the reactivation of dormant herpesviruses

Dormant herpesviruses induce their reactivation via a previously unknown cellular mechanism mediated by a viral microRNA. Würzburg researchers show this in the journal "Nature".

5 May 2022

People with highest levels of antioxidants less likely to develop dementia, finds study

People with higher levels of antioxidants in their blood may be less likely to develop dementia, according to a study published in the May 4, 2022, online issue of Neurology, the medical journal of the American Academy of Neurology.

4 May 2022

Study examines whether having MS plays a role in regular cancer screenings and diagnosis

Women with multiple sclerosis (MS) are less likely to have breast cancers detected through cancer screenings than women without MS, according to new research published in the April 27, 2022, online issue of Neurology, the medical journal of the American Academy of Neurology.

27 Apr 2022

Prevalence of multiple sclerosis in Black and white people is similarly high, study says

The rate of multiple sclerosis (MS) cases varies greatly by race and ethnicity. A new study suggests that the prevalence of MS in Black and white people is similarly high, while much lower in Hispanic and Asian people.

27 Apr 2022

Sclerosis News and Research

Antibiotic rifampicin attenuates C9orf72-linked dementia in genetically modified mice

Pioneering study could transform the treatment landscape for babies with infantile spasms

Researchers analyze the development and genetic profile of brain's immune cells

Mice study links dietary cholesterol with exacerbation of influenza

Epilepsy drug inhibits the growth of NF1 tumors in mice

Study supports the use of age-specific risk prediction scores for dementia

Experimental drug more effective than existing FDA-approved medications for ALS

Exposure to cold and warm temperatures causes changes in gene expression in various organs

Study shows how MS patients treated with Rituximab react to COVID-19 vaccination

The promise of RNA medicine is targeted and personalized

Maternal antidepressant use during pregnancy does not increase epilepsy risk in babies

Rutgers study identifies key protein for brain stem cell longevity

New methods can make spinal cord less excitable and could be used to treat muscle spasms

Report highlights the need for an office to support autoimmune disease research across NIH institutes

Detecting treatments for autoimmune disease using an immune ‘fingerprint’

NIH launches clinical study to evaluate an investigational preventative vaccine for Epstein-Barr virus

Viral microRNA acts as a master regulator to induce the reactivation of dormant herpesviruses

People with highest levels of antioxidants less likely to develop dementia, finds study

Study examines whether having MS plays a role in regular cancer screenings and diagnosis

Prevalence of multiple sclerosis in Black and white people is similarly high, study says

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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