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Mosaic Therapeutics closes $28m series A funding and appoints Brian Gladsden as CEO

Mosaic Therapeutics, an oncology therapeutics company dedicated to resolving cancer’s complexity to power new treatments for patients, today announced the close of its $28 million series A funding round.

From Mosaic Therapeutics 4 Apr 2023

Clinical trial may change the paradigm of care for patients with ALK-driven high-risk neuroblastoma

In a significant step for the treatment of neuroblastoma, an international group of researchers led by Children's Hospital of Philadelphia (CHOP), Winship Cancer Institute of Emory University and the New Approaches to Neuroblastoma Therapy (NANT) Consortium has shown that the targeted therapy lorlatinib is safe and effective in treating high-risk neuroblastoma.

4 Apr 2023

Mosaic Therapeutics closes $28m series A funding and appoints Brian Gladsden as CEO

Company developing targeted oncology therapies spun out of world-leading research at the Wellcome Sanger Institute, in collaboration with the Netherlands Cancer Institute.

From Mosaic Therapeutics 4 Apr 2023

UCSD engineers develop a biodegradable polymer system to treat rheumatoid arthritis

A team led by engineers at the University of California San Diego has developed a biodegradable polymer system to treat rheumatoid arthritis, an autoimmune and inflammatory disease, by working in concert with the power of the human immune system.

4 Apr 2023

Optibrium appoints computational modelling expert, Dr Hamed Tabatabaei Ghomi as Head of Research

Optibrium, a leading developer of software and AI solutions for drug discovery, today announced the appointment of Dr Hamed Tabatabaei Ghomi as Head of Research.

From Optibrium Ltd. 4 Apr 2023

Orbit Discovery and Evergreen Discovery collaborate to discover peptides for targeting radiopharmaceuticals

Evergreen Discovery (Evergreen), a leading radiopharmaceutical drug development company with a focus on the treatment and diagnosis of cancer.

From Orbit Discovery 3 Apr 2023

Lipid Nanoparticles (LNPs) and DNA delivery – unlocking the future of medical research

In this interview, Kate Stumpo speaks to Michael Girgis about Lipid nano particles, and the future of the field.

From Bruker Daltonics 31 Mar 2023

SARS-CoV-2 infection disrupts the RNA modifications, study reports

Coronavirus disease (COVID-19) hijacks parts of infected cells' vital RNA machinery, thereby blocking important functions in the cells. These damaging changes in the RNA can likely be reversed, potentially leading to new drugs against COVID-19, University of Gothenburg researchers show.

29 Mar 2023

Pneumolysin toxin holds promise for developing therapies against Streptococcus pneumoniae

In a recent study published in the journal PLoS ONE, researchers in Spain performed a systematic review of pneumolysin (PLY) toxin as a molecular target to develop novel therapeutics against Streptococcus pneumoniae.

27 Mar 2023

Global search for sustainable protein sources: Turning to insects, weeds, and fungi to meet rising demand

Researchers explore novel foods such as unconventional legume crops, aquatic weeds, edible fungi, and insects as sources of proteins alternative to meat.

26 Mar 2023

Researchers discover how a mutation in the desmosomal gene leads to arrhythmogenic cardiomyopathy

Mutations in genes that form the desmosome are the most common cause of the cardiac disease arrhythmogenic cardiomyopathy (ACM), which affects one in 2000 to 5000 people worldwide.

22 Mar 2023

Co-infection with MRSA ‘superbug’ could make COVID-19 outcomes even more deadly

Global data shows nearly 10 per cent of severe COVID-19 cases involve a secondary bacterial co-infection – with Staphylococcus aureus, also known as Staph A., being the most common organism responsible for co-existing infections with SARS-CoV-2.

21 Mar 2023

Einstein and Montefiore receive $30 million NIH grant to advance translational science and health equity

Albert Einstein College of Medicine and Montefiore Health System have received a seven-year, $30 million grant from the National Institutes of Healthto continue support for the Harold and Muriel Block Institute for Clinical and Translational Research at Einstein and Montefiore.

21 Mar 2023

Novel RNA sense-and-respond circuit harnesses the force of enzymes to develop better drugs

More than twelve billion doses of mRNA vaccines have been administered globally since the start of the COVID pandemic, saving millions of lives. But RNA-based therapies for other diseases have so far proven more challenging to develop.

20 Mar 2023

£3 million funding to support the development of new antimicrobials for cystic fibrosis patients

Today (16 March 2023), Cystic Fibrosis (CF) Syndicate in Antimicrobial Resistance (AMR) announces a £3 million Collaborative Discovery Programme for drug discovery innovators to accelerate the development of new treatments for people with CF.

20 Mar 2023

Trial shows encouraging results for neoadjuvant dual immunotherapy and chemotherapy in patients with resectable NSCLC

In a Phase II trial led by researchers from The University of Texas MD Anderson Cancer Center, adding ipilimumab to a neoadjuvant, or pre-surgical, combination of nivolumab plus platinum-based chemotherapy, resulted in a major pathologic response (MPR) in half of all treated patients with early-stage, resectable non-small cell lung cancer (NSCLC).

16 Mar 2023

Researchers design a virus-resistant, more useful E. coli bacteria

In a step forward for genetic engineering and synthetic biology, researchers have modified a strain of Escherichia coli bacteria to be immune to natural viral infections while also minimizing the potential for the bacteria or their modified genes to escape into the wild.

15 Mar 2023

Translation News and Research

Mosaic Therapeutics closes $28m series A funding and appoints Brian Gladsden as CEO

Clinical trial may change the paradigm of care for patients with ALK-driven high-risk neuroblastoma

Mosaic Therapeutics closes $28m series A funding and appoints Brian Gladsden as CEO

UCSD engineers develop a biodegradable polymer system to treat rheumatoid arthritis

Optibrium appoints computational modelling expert, Dr Hamed Tabatabaei Ghomi as Head of Research

Orbit Discovery and Evergreen Discovery collaborate to discover peptides for targeting radiopharmaceuticals

Lipid Nanoparticles (LNPs) and DNA delivery – unlocking the future of medical research

SARS-CoV-2 infection disrupts the RNA modifications, study reports

Pneumolysin toxin holds promise for developing therapies against Streptococcus pneumoniae

Global search for sustainable protein sources: Turning to insects, weeds, and fungi to meet rising demand

Researchers discover how a mutation in the desmosomal gene leads to arrhythmogenic cardiomyopathy

Co-infection with MRSA ‘superbug’ could make COVID-19 outcomes even more deadly

Einstein and Montefiore receive $30 million NIH grant to advance translational science and health equity

Novel RNA sense-and-respond circuit harnesses the force of enzymes to develop better drugs

£3 million funding to support the development of new antimicrobials for cystic fibrosis patients

Trial shows encouraging results for neoadjuvant dual immunotherapy and chemotherapy in patients with resectable NSCLC

Researchers design a virus-resistant, more useful E. coli bacteria

Research identifies western diet-induced microbial and metabolic contributors to liver disease

Specific enzyme produced in liver cancer cells could turn a molecule into potential anticancer drug

Electronic messaging tactics increase flu vaccination rates, Danish study shows

Industry Focus eBook - Cell biology (5th edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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