Immune System News and Research

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Complete genetic map of scleroderma opens door for diagnosis and targeted treatment

Scleroderma is an autoimmune disease that affects one out of every 10,000 people in Europe and North America, mostly middle-aged women, and causes death in a high percentage of cases.

11 Apr 2016

Mouse-based study shows exercise decreases cancer incidence, slows tumor growth

When you're pounding along an icy pavement or sweating through a gym workout, you try to remind yourself of the many health benefits of exercise. Between gasps, you can say that a healthy, fit lifestyle helps prevents obesity, a worldwide problem of increasing magnitude that has been linked to cardiovascular disease and diabetes.

11 Apr 2016

Zika virus may be linked to autoimmune disorder that attacks the brain's myelin

The Zika virus may be associated with an autoimmune disorder that attacks the brain's myelin similar to multiple sclerosis, according to a small study that is being released today and will be presented at the American Academy of Neurology's 68th Annual Meeting in Vancouver, Canada, April 15 to 21, 2016.

11 Apr 2016

Innovative HIV vaccine candidate generates protection against repeated AIDS virus exposures

Mymetics Corporation, a pioneer in the research and development of virosome-based vaccines to prevent transmission of human infectious diseases across mucosal membranes, announced today that its innovative HIV vaccine candidate has shown to generate significant protection in groups of twelve female monkeys against repeated AIDS virus exposures during part of the preclinical study.

11 Apr 2016

HPV vaccination may be beneficial for CKD patients but not for kidney transplant recipients

Human papillomavirus (HPV) vaccination stimulates robust and sustained immune responses in girls and young women with chronic kidney disease (CKD) and those on dialysis, but less optimal responses to the vaccine were observed among those with a kidney transplant.

11 Apr 2016

Cigarette smoking, viral infections may reduce effectiveness of COPD symptom-reliever medication

New study backs up observations in Chronic Obstructive Pulmonary Disease (COPD) patients showing reduced effectiveness of symptom-reliever medication (β2-adrenoceptor agonists) in flare-ups linked to cigarette smoking and infection with viruses such as influenza.

11 Apr 2016

Novel nanoparticle drug delivery system for enhanced tumor penetration of cancer drugs

For more than a decade, biomedical researchers have been looking for better ways to deliver cancer-killing medication directly to tumors in the body. Tiny capsules, called nanoparticles, are now being used to transport chemotherapy medicine through the bloodstream, to the doorstep of cancerous tumors.

11 Apr 2016

Researchers identify gene crucial to development of coeliac disease

Coeliac disease is a chronic, immunological disease that is manifested as intolerance to gluten proteins present in wheat, rye and barley. This intolerance leads to an inflammatory reaction in the small intestine that hampers the absorption of nutrients. The only treatment is a strict, life-long, gluten-free diet.

11 Apr 2016

Researchers identify severe side effects of Clozapine drug

Clozapine (CLZ) is a "gold standard" drug for managing treatment-resistant schizophrenia (TRS), who do not respond adequately to first-line antipsychotics.

7 Apr 2016

Vanderbilt's A.S.A.P sees increase in number of patients treated for alpha-gal syndrome

Vanderbilt's Asthma, Sinus and Allergy Program (A.S.A.P) has seen an increase in the number of patients being treated for alpha-gal syndrome, commonly known as the red meat allergy linked to tick bites.

7 Apr 2016

Genetically modified pig hearts can survive for more than 2 years after transplantation into baboons

Could organs explanted from other mammals save human lives someday? A new study shows that genetically modified pig hearts developed by US and Ludwig-Maximilians-Universitaet in Munich researchers can survive for more than up to 2½ years when transplanted into baboons.

7 Apr 2016

Salk scientists identify specific cellular switches that clear dying, dead neurons

By adolescence, your brain already contains most of the neurons that you'll have for the rest of your life. But a few regions continue to grow new nerve cells--and require the services of cellular sentinels, specialized immune cells that keep the brain safe by getting rid of dead or dysfunctional cells.

7 Apr 2016

Researchers develop innovative method for gene transfer

Researchers have developed a new and highly efficient method for gene transfer. The technique, which involves culturing and transfecting cells with genetic material on an array of carbon nanotubes, appears to overcome the limitations of other gene editing technologies.

7 Apr 2016

Ludwig, CRI launch Phase 1/2 trial of combination immunotherapy for advanced ovarian cancer

Ludwig Cancer Research and the Cancer Research Institute have launched a Phase 1/2 clinical trial of combination immunotherapy for advanced ovarian cancer. The international, multicenter trial is led by George Coukos, director of the Ludwig Institute for Cancer Research, Lausanne and Brad Monk, director of Gynecologic Oncology at St. Joseph's Hospital and Medical Center.

7 Apr 2016

New immune-suppressing therapy leads to longer survival for cross-species heart transplant

A new immune-suppressing therapy has led to the longest survival yet for a cross-species heart transplant, according to new research conducted in part by researchers at the University of Maryland School of Medicine.

7 Apr 2016

Structure-based approach could lead to effective HIV vaccine

It's been known for some time that the immune system can produce antibodies capable of "neutralizing" HIV, and stopping the AIDS-causing virus dead in its tracks.

7 Apr 2016

First patient enrolled in type 1 diabetes cell therapy trial

A clinical trial studying the body's ability to fight type 1 diabetes using cell therapy has used the method on its first participant. "The Sanford Project: T-Rex Study" is a collaborative study between Sanford Health and Caladrius Biosciences, Inc., for adolescents with newly onset type 1 diabetes.

7 Apr 2016

Immune System News and Research

Complete genetic map of scleroderma opens door for diagnosis and targeted treatment

Mouse-based study shows exercise decreases cancer incidence, slows tumor growth

Zika virus may be linked to autoimmune disorder that attacks the brain's myelin

Innovative HIV vaccine candidate generates protection against repeated AIDS virus exposures

HPV vaccination may be beneficial for CKD patients but not for kidney transplant recipients

Cigarette smoking, viral infections may reduce effectiveness of COPD symptom-reliever medication

Novel nanoparticle drug delivery system for enhanced tumor penetration of cancer drugs

Researchers identify gene crucial to development of coeliac disease

Researchers identify severe side effects of Clozapine drug

Vanderbilt's A.S.A.P sees increase in number of patients treated for alpha-gal syndrome

Genetically modified pig hearts can survive for more than 2 years after transplantation into baboons

Salk scientists identify specific cellular switches that clear dying, dead neurons

Researchers develop innovative method for gene transfer

Ludwig, CRI launch Phase 1/2 trial of combination immunotherapy for advanced ovarian cancer

New immune-suppressing therapy leads to longer survival for cross-species heart transplant

Structure-based approach could lead to effective HIV vaccine

First patient enrolled in type 1 diabetes cell therapy trial

Autologous haematopoietic stem cell transplantation promise for myasthenia gravis

Children of salmon-eating mothers less likely to develop asthma

Researchers develop mouse model for testing vaccines, therapeutics to battle Zika virus

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