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Researchers refine diagnostic tools to predict treatment outcomes for children with neuroblastoma

Oncology researchers studying gene mutations in the childhood cancer neuroblastoma are refining their diagnostic tools to predict which patients are more likely to respond to drugs called ALK inhibitors that target such mutations. Removing some of the guesswork in diagnosis and treatment, the researchers say, may lead to more successful outcomes for children with this often-deadly cancer.

11 Nov 2014

FDA accepts Amgen's evolocumab BLA for review

Amgen today announced that the U.S. Food and Drug Administration has accepted for review Amgen's Biologics License Application (BLA) for evolocumab for the treatment of high cholesterol.

11 Nov 2014

Sulindac drug can protect against oxidative damage due to AMD

While oxygen is essential to our planet's life force and the way we function and stay healthy, high concentrations referred to as oxidative stress may very well be the cause of more than 70 widely-spread diseases such as cancer, heart disease, neurodegenerative diseases, and eye diseases including macular degeneration.

11 Nov 2014

Anxiety can accelerate conversion to Alzheimer's disease for people with mild cognitive impairment

People with mild cognitive impairment (MCI) are at increased risk of converting to Alzheimer's disease within a few years, but a new study warns the risk increases significantly if they suffer from anxiety.

11 Nov 2014

Innovative program benefits incapacitated patients with no family or friends

A Regenstrief Institute and Eskenazi Health study reports on an innovative program that trains and supervises volunteers who act as advocates for adults and seniors who are unable to make their own decisions due to conditions like Alzheimer's disease or coma, but have no family or friends to help them.

11 Nov 2014

UW SMPH awarded $70 million grant to continue work on Inner-City Asthma Consortium

The National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, has awarded the University of Wisconsin School of Medicine and Public Health a seven-year, $70 million grant for its continuing work on the Inner-City Asthma Consortium (ICAC) -- a nationwide clinical research network to evaluate and develop promising new immune-based treatments.

11 Nov 2014

New study finds that it is possible to distinguish between different hemorrhagic fevers

A new study has found it is possible to distinguish between different hemorrhagic fevers, including Marburg (Ebola cousin) and Lassa before the person becomes symptomatic.

11 Nov 2014

Study points to major role of obesity in triggering, prolonging autoimmune diseases

Autoimmune diseases like Crohn's Disease and multiple sclerosis, in which the immune system attacks its own body rather than predatory invaders, affect 5-20% of the global community. A study published recently in Autoimmunity Reviews by Prof. Yehuda Shoenfeld, the Laura Schwarz-Kipp Chair for Research of Autoimmune Diseases at Tel Aviv University's Sackler Faculty of Medicine and Head of Zabludowicz Center for Autoimmune Diseases at Chaim Sheba Medical Center, Tel Hashomer, points to the major role obesity plays in triggering and prolonging these autoimmune diseases.

11 Nov 2014

Mice may hold clues in development of ADHD, autism and bipolar disorder

A darting mouse may hold an important clue in the development of Attention Deficit Hyperactivity Disorder (ADHD), autism and bipolar disorder, according to a study by a Vanderbilt University-led research team recently published in the Proceedings of the National Academy of Sciences.

11 Nov 2014

New treatment could halt growth of tumours in prostate cancer patients

Scientists believe a new treatment, shown to be effective in mice, could halt the growth of tumours in patients with prostate cancer.

11 Nov 2014

U-M study reveals that mothers' education can predict children's academic success

A mother knows best--and the amount of education she attains can predict her children's success in reading and math. In fact, that success is greater if she had her child later in life, according to a new University of Michigan study.

11 Nov 2014

MicroMatrices, Advanced Cell Diagnostics sign preferred partnership agreement

MicroMatrices, a service provider specialised in high resolution cell type-specific analysis to characterise toxicological responses in different cell types in tissue, today announced a preferred partnership agreement with Advanced Cell Diagnostics, Inc., a leader in the field of molecular pathology and developer of cell and tissue-based analysis tools.

From Advanced Cell Diagnostics 11 Nov 2014

New drug combination shows promise as effective, safe treatment for rheumatoid arthritis

A new drug combination for rheumatoid arthritis treats the disease just as well as other intensive treatment strategies but with less medication and fewer side effects at a significantly lower cost. Doctoral researcher Diederik De Cock (KU Leuven) describes the strategy in a new study published in Annals of Rheumatic Diseases.

11 Nov 2014

New model explains how immune cells recognize, destroy bacteria

The innate immune system serves as the body's specialized armed forces division, comprised of a host of defense mechanisms used to battle bacterial infections. Among the system's warriors are white blood cells including the specialized macrophages, which maintain constant surveillance for foreign intruders or pathogens, functioning as the body's first line of defense, poised to attack at barrier sites including the skin, lungs and intestines.

11 Nov 2014

U of T, Chematria and IBM partner to find new treatments for Ebola virus

The University of Toronto, Chematria and IBM are combining forces in a quest to find new treatments for the Ebola virus.

11 Nov 2014

Patients who receive care from nurses with bachelor's degrees have shorter stays, fewer readmissions

Patients in an eastern academic medical center who received most of their nursing care from nurses with bachelor of science degrees had better care, fewer readmissions and shorter stays, according to a University of Michigan study.

11 Nov 2014

Researchers explain interaction between HNRNPA2B1 protein and pancreatic cancer development

Researchers from the University of Barcelona have described an interaction between the protein HNRNPA2B1 and pancreatic cancer development which remained unknown. The study, published in the journal Gastroenterology, has proved in human cancer cell lines that this protein is essential to the correct activity of the oncogenic protein KRAS, related to cancer start and development.

11 Nov 2014

Cigarette smoking increases risk of developing second smoking-associated cancer

Results of a federally-funded pooled analysis of five prospective cohort studies indicate that cigarette smoking prior to the first diagnosis of lung (stage I), bladder, kidney or head and neck cancer increases risk of developing a second smoking-associated cancer. This is the largest study to date exploring risk of second cancers among current smokers.

11 Nov 2014

Laundry detergent pods are dangerous for young children

Laundry detergent pods began appearing on U.S. store shelves in early 2010, and people have used them in growing numbers ever since. The small packets can be tossed into a washing machine without ever having to measure out a liquid or powder. The convenience, though, has come with risks for young children.

11 Nov 2014

Olympus to host fifth annual neuroimaging symposium in conjunction with 2014 annual meeting of the Society for Neuroscience

Olympus is hosting its fifth annual neuroimaging symposium in conjunction with the 2014 annual meeting of the Society for Neuroscience (SfN) on Monday, November 17 at 6:30pm in Washington DC. The Olympus Neuroimaging Symposium and reception will be held at the Marriott Marquis Washington, DC, 901 Massachusetts Avenue NW, in the Capitol and Congress ballrooms. It is open to all media and registered SfN attendees.

From Evident Corporation - Life Sciences 10 Nov 2014

Research News and Research

Researchers refine diagnostic tools to predict treatment outcomes for children with neuroblastoma

FDA accepts Amgen's evolocumab BLA for review

Sulindac drug can protect against oxidative damage due to AMD

Anxiety can accelerate conversion to Alzheimer's disease for people with mild cognitive impairment

Innovative program benefits incapacitated patients with no family or friends

UW SMPH awarded $70 million grant to continue work on Inner-City Asthma Consortium

New study finds that it is possible to distinguish between different hemorrhagic fevers

Study points to major role of obesity in triggering, prolonging autoimmune diseases

Mice may hold clues in development of ADHD, autism and bipolar disorder

New treatment could halt growth of tumours in prostate cancer patients

U-M study reveals that mothers' education can predict children's academic success

MicroMatrices, Advanced Cell Diagnostics sign preferred partnership agreement

New drug combination shows promise as effective, safe treatment for rheumatoid arthritis

New model explains how immune cells recognize, destroy bacteria

U of T, Chematria and IBM partner to find new treatments for Ebola virus

Patients who receive care from nurses with bachelor's degrees have shorter stays, fewer readmissions

Researchers explain interaction between HNRNPA2B1 protein and pancreatic cancer development

Cigarette smoking increases risk of developing second smoking-associated cancer

Laundry detergent pods are dangerous for young children

Olympus to host fifth annual neuroimaging symposium in conjunction with 2014 annual meeting of the Society for Neuroscience

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