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miRagen Therapeutics establishes SAB

miRagen Therapeutics, Inc., a biopharmaceutical company focused on improving patients’ lives by developing innovative microRNA (miRNA)-based therapeutics for cardiovascular and muscle disease, announced today the formation of the company’s world renowned Scientific Advisory Board (SAB). The SAB was established to provide miRagen with valuable guidance in developing an extensive pipeline of microRNA-based drugs and is comprised of leaders who are internationally recognized experts in their respective fields.

12 Jan 2010

Lead even below level "of concern" for children may impair kidney function

Small amounts of lead in the bodies of healthy children and teens — amounts well below the levels defined as "concerning" by the U.S. Centers for Disease Control and Prevention (CDC) — may worsen kidney function, according to a Johns Hopkins Children's Center study published in the Jan. 11 issue of Archives of Internal Medicine.

12 Jan 2010

Stem cell therapy holds promise as potential alternative to bone grafting operations

A study published this week reinforces the potential value of stem cells in repairing major injuries involving the loss of bone structure.

12 Jan 2010

Salt Lake City research center joins international drug trial program for painful menstrual cramps

A leading clinical research center in Salt Lake City has joined an international trial program to test an experimental new drug designed to treat painful menstrual cramps, or dysmenorrhea, a condition that affects between 45 and 90 percent of women of childbearing age in the United States. Although not life threatening, dysmenorrhea can be debilitating and psychologically taxing and is one of the leading causes of absenteeism from work and school.

12 Jan 2010

PDGFR's role in new blood vessel formation may explain cardiovascular side effects

A growth factor that is a common target of cancer drugs also plays an important role in the heart's response to stress, researchers at The University of Texas M. D. Anderson Cancer Center report online this week in the Journal of Clinical Investigation.

12 Jan 2010

Researchers study VA111913 drug as a possible treatment for dysmenorrhea

A leading clinical research center in Austin has joined an international research program to study an investigational drug designed as a possible treatment for painful menstrual cramps, or dysmenorrhea, a condition that affects between 45 and 90 percent of women of childbearing age in the United States.

12 Jan 2010

New therapeutic treatment may provide a potential alternative to bone grafting operation

A study published this week reinforces the potential value of stem cells in repairing major injuries involving the loss of bone structure.

12 Jan 2010

BioMarin Pharmaceutical commences BMN 195 Phase 1 clinical study for DMD

BioMarin Pharmaceutical Inc. announced today that the first subject has initiated treatment in the Phase 1 clinical study of BMN 195, a small molecule utrophin upregulator, for the treatment of Duchenne muscular dystrohpy (DMD). Initial top-line results are expected in the third quarter of 2010.

12 Jan 2010

BIDMC scientists identify new pathway to address the problem of photophobia during migraines

Ask anyone who suffers from migraine headaches what they do when they're having an attack, and you're likely to hear "go into a dark room." And although it's long been known that light makes migraines worse, the reason why has been unclear.

11 Jan 2010

Research into "chemical chaperone" may lead to new treatments for heart attacks

Researchers at the Indiana University and Stanford University schools of medicine have determined how a "chemical chaperone" does its job in the body, which could lead to a new class of drugs to help reduce the muscle damage caused by heart attacks.

10 Jan 2010

New stem cell therapies to feature at 5th Annual Stem Cell Summit in NYC

Six new stem cell therapies, all forecast to reach physicians in 2010, will be featured at the 5th Annual Stem Cell Summit on February 16 in New York City. These new therapies include allograft products, innovative forms of autologous stem cell technologies, and at least one FDA-approved stem cell drug. New studies showing rehydration of the disc nucleus, regeneration of new heart muscle and others are also on the agenda.

9 Jan 2010

Chinese researchers become the world's fifth most prolific contributors to regenerative medicine

Chinese researchers have become the world's fifth most prolific contributors to peer-reviewed scientific literature on clock-reversing regenerative medicine even as a skeptical international research community condemns the practice of Chinese clinics administering unproven stem cell therapies to domestic and foreign patients.

8 Jan 2010

Scientists identify gene underlying a disease that causes temporary paralysis of skeletal muscle

Scientists have identified a gene underlying a disease that causes temporary paralysis of skeletal muscle. The finding, they say, illustrates how investigations of rare genetic diseases can drive insights into more common ones.

8 Jan 2010

Preliminary studies show cancer vaccine may reduce tumor cells in CML patients

Johns Hopkins Kimmel Cancer Center researchers say preliminary studies show that a vaccine made with leukemia cells may be able to reduce or eliminate the last remaining cancer cells in some chronic myeloid leukemia (CML) patients taking the drug Imatinib mesylate (Gleevec).

8 Jan 2010

CRF awards $1.75 million in 11 new grants to researchers to find a cure for cystinosis

The Cystinosis Research Foundation of Irvine, Calif., announced it awarded $1.75 million in 11 new grants to researchers in the United States, Canada, Belgium and Italy who are working to find a cure for cystinosis, a rare, deadly metabolic and genetic disease that afflicts about 500 children and young adults in the U.S. and 2,000 worldwide.

7 Jan 2010

Muscle Flex to launch Muscle Flex VATA Brasil Sports and Active Wear Line

Muscle Flex Inc. (www.MuscleFlex.com) announced today that it has scheduled January 25, 2010 for the official launch of its Muscle Flex VATA Brasil™ (www.MuscleFlexVATA.com) Sports and Active Wear Line and plans to establish the line with a high profile premiere, details to be announced.

7 Jan 2010

Cedars-Sinai Heart Institute selected as top 25 hospitals for cardiac bypass surgery

Worth magazine has selected Cedars-Sinai Heart Institute as one of the United States' top 25 hospitals for cardiac bypass surgery.

7 Jan 2010

Tips to prevent injuries while shoveling

Snow shoveling tends to be an unpleasant task—this mundane seasonal chore combines heavy lifting and cold weather, resulting in possible injuries to the back, shoulder muscles if shovelers do not take the proper precautions. The American Academy of Orthopaedic Surgeons (AAOS) has recommendations to help you stay safe while clearing snow so you can still have some winter fun.

7 Jan 2010

Researchers identify new approach to eliminate side effects of drugs

Researchers at the Stanford University School of Medicine have taken an early step toward identifying a new approach to drug discovery that may eventually yield drugs with fewer side effects.

7 Jan 2010

Study finds self-management alone may effectively treat knee osteoarthritis

Researchers participating in the Multidimensional Intervention for Early Osteoarthritis of the Knee (Knee Study) determined that physically inactive, middle-aged people with symptomatic osteoarthritis benefitted equally from strength training regimens, self-management programs, or a combination of the two. Details of this study are available in the January 2010 issue of Arthritis Care & Research, a journal published by Wiley-Blackwell on behalf of the American College of Rheumatology.

6 Jan 2010

Muscle News and Research

miRagen Therapeutics establishes SAB

Lead even below level "of concern" for children may impair kidney function

Stem cell therapy holds promise as potential alternative to bone grafting operations

Salt Lake City research center joins international drug trial program for painful menstrual cramps

PDGFR's role in new blood vessel formation may explain cardiovascular side effects

Researchers study VA111913 drug as a possible treatment for dysmenorrhea

New therapeutic treatment may provide a potential alternative to bone grafting operation

BioMarin Pharmaceutical commences BMN 195 Phase 1 clinical study for DMD

BIDMC scientists identify new pathway to address the problem of photophobia during migraines

Research into "chemical chaperone" may lead to new treatments for heart attacks

New stem cell therapies to feature at 5th Annual Stem Cell Summit in NYC

Chinese researchers become the world's fifth most prolific contributors to regenerative medicine

Scientists identify gene underlying a disease that causes temporary paralysis of skeletal muscle

Preliminary studies show cancer vaccine may reduce tumor cells in CML patients

CRF awards $1.75 million in 11 new grants to researchers to find a cure for cystinosis

Muscle Flex to launch Muscle Flex VATA Brasil Sports and Active Wear Line

Cedars-Sinai Heart Institute selected as top 25 hospitals for cardiac bypass surgery

Tips to prevent injuries while shoveling

Researchers identify new approach to eliminate side effects of drugs

Study finds self-management alone may effectively treat knee osteoarthritis

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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