Immunization News and Research

RSS

Pregnant and lactating women did not experience increased reactions after COVID-19 vaccination

A survey of more than 17,000 pregnant and lactating individuals who received the COVID-19 vaccine showed that the individuals did not experience symptoms any more severe than their non-pregnant counterparts.

17 Aug 2021

Vaccinating previously infected induces more potent antibodies less susceptible to escape from SARS-CoV-2 variants

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is the causal agent of the coronavirus disease 2019 (COVID-19) pandemic, which has claimed more than 4.3 million lives worldwide. Even after implementing various measures, such as vaccination and social restrictions, SARS-CoV-2 and its variants of concern (VoC) leave the world's public health systems and economies in turmoil.

16 Aug 2021

In rural America, twisting arms to take a covid vaccine first takes trust

Lee Wright was hard at work, constructing a nail salon near the city's abandoned hospital, when Jody Johnson stopped by to introduce himself on a recent afternoon.

16 Aug 2021

Primate study shows benefit of mRNA vaccine booster shot against SARS-CoV-2 variants

In a recent bioRxiv* preprint research paper, a large group of US scientists demonstrate how a booster dose of the mRNA-1273 vaccine can substantially improve both the potency and range of neutralizing antibody responses and mediate protection against upper and lower airway infection by a range of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern – even those relatively resistant to in vitro neutralization.

16 Aug 2021

World-first trial of third dose COVID-19 booster vaccine shows improved protection in transplant patients

Scientists with the Ajmera Transplant Centre at UHN have conducted a first-in-the-world randomized placebo-controlled trial of third dose COVID-19 booster vaccine for transplant patients that shows substantially improved protection.

14 Aug 2021

CDC recommends additional dose of mRNA COVID-19 vaccine in moderately to severely immunocompromised people

Today, I signed CDC's Advisory Committee on Immunization Practices' (ACIP) recommendation that endorsed the use of an additional dose of COVID-19 vaccine for people with moderately to severely compromised immune systems after an initial two-dose vaccine series.

13 Aug 2021

Evaluation of mRNA vaccine responses with a surrogate SARS-CoV-2 viral neutralization assay

In the current study, the authors evaluate several different competitive ELISAs that could be used to measure serum antibodies.

11 Aug 2021

Plant-based virus-like particle vaccine induces durable immune response against SARS-CoV-2 variants

Scientists from Germany and Belgium have recently described the immunogenicity of a plant-based virus-like particle vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The vaccine induces robust antibody and T cell responses for at least 6 months. Moreover, the vaccine demonstrates potent neutralizing efficacy against the B.1.1.7, B.1.351, and P1 variants of SARS-CoV-2.

11 Aug 2021

Study shows efficacy of gamma irradiation of SARS-CoV-2 vaccine candidate in mouse model

A new study reports a more rapid method of viral inactivation in an effort to increase the appeal of inactivated viral vaccines against the COVID-19 pandemic.

10 Aug 2021

Double vaccinated three times less likely to test positive for COVID-19 than unvaccinated, says study

In new research, scientists at Imperial College London report that double vaccinated individuals could be three times less likely than unvaccinated people to test positive for SARS-CoV-2 infection.

6 Aug 2021

Vaccination may protect against SARS-CoV-2 infection at the eye surface

Researchers in Australia have conducted a study showing that vaccination against coronavirus disease 2019 (COVID-19) induces key antibodies at the eye surface that may help to protect against the transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

5 Aug 2021

How does the mRNA/lipid nanoparticle platform promote protective adaptive immunity against SARS-CoV-2?

Modified mRNA combined with lipid nanoparticles may be beneficial in boosting adaptive immunity against SARS-CoV-2. Research led by Botond Z. Igyártó from Thomas Jefferson University’s Department of Microbiology and Immunology in Pennsylvania recently found that the lipid nanoparticles induce protective adaptive immune responses with antibody titers against lethal doses of the virus.

5 Aug 2021

Two monoclonal antibodies broadly neutralize SARS-CoV-2 variants of concern

Researchers in the United States and Canada have described the structural basis and mode of action for two monoclonal antibodies that potently neutralize severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

4 Aug 2021

Heterologous prime-boost vaccination induces robust mucosal and systemic immunity against SARS-CoV-2

Scientists from Germany and Italy recently demonstrated the benefits of intramuscular/intranasal heterologous prime-boost vaccination regimen against coronavirus disease 2019 (COVID-19).

4 Aug 2021

‘Wisdom and fear’ lead 90% of U.S. seniors to covid vaccines

Amid the latest surge in covid-19 cases and hospitalizations, the United States on Tuesday hit a milestone that some thought was unattainable: 90% of people 65 and older are at least partly vaccinated against the disease.

4 Aug 2021

SARS-CoV-2 Delta and Delta AY.1 variant show similar Covaxin-induced neutralization

A new study from India suggests that the Indian-made Covaxin whole-virus inactivated vaccine against the SARS-CoV-2 retains significant efficacy against the newer delta variants of the virus.

3 Aug 2021

Unvaccinated and vaccinated have similar viral load in communities high in SARS-CoV-2 delta

The findings reveal that vaccinated and unvaccinated individuals exhibit similar viral loads following delta infection and that vaccine breakthrough cases have the potential to transmit infection to others. The study is currently available on the medRxiv* preprint server.

3 Aug 2021

CHOP researchers identify two proteins that could be used for a potential NTHi vaccine

Scientists at Children's Hospital of Philadelphia have identified two proteins that could be used for a potential vaccine against nontypeable Haemophilus influenzae (NTHi).

2 Aug 2021

Intradermal administration of low-dose mRNA COVID-19 vaccine induces strong immune response, study finds

Scientists in the Netherlands recently conducted an open-level, randomized-controlled trial to evaluate the safety and immunogenicity of fractional intradermal doses of the mRNA-based COVID-19 vaccine mRNA-1273 (Moderna). The trial findings reveal that the fractional dose regimen of the Moderna vaccine is well tolerated and safe and is capable of inducing robust antibody responses in vaccine recipients. The study is currently available on the medRxiv* preprint server.

2 Aug 2021

Bus stop by bus stop, Denver-area officials microtarget vaccine hesitancy

John Letson had seen too many apocalyptic movies to feel comfortable getting a covid-19 vaccine initially.

30 Jul 2021

Immunization News and Research

Pregnant and lactating women did not experience increased reactions after COVID-19 vaccination

Vaccinating previously infected induces more potent antibodies less susceptible to escape from SARS-CoV-2 variants

In rural America, twisting arms to take a covid vaccine first takes trust

Primate study shows benefit of mRNA vaccine booster shot against SARS-CoV-2 variants

World-first trial of third dose COVID-19 booster vaccine shows improved protection in transplant patients

CDC recommends additional dose of mRNA COVID-19 vaccine in moderately to severely immunocompromised people

Evaluation of mRNA vaccine responses with a surrogate SARS-CoV-2 viral neutralization assay

Plant-based virus-like particle vaccine induces durable immune response against SARS-CoV-2 variants

Study shows efficacy of gamma irradiation of SARS-CoV-2 vaccine candidate in mouse model

Double vaccinated three times less likely to test positive for COVID-19 than unvaccinated, says study

Vaccination may protect against SARS-CoV-2 infection at the eye surface

How does the mRNA/lipid nanoparticle platform promote protective adaptive immunity against SARS-CoV-2?

Two monoclonal antibodies broadly neutralize SARS-CoV-2 variants of concern

Heterologous prime-boost vaccination induces robust mucosal and systemic immunity against SARS-CoV-2

‘Wisdom and fear’ lead 90% of U.S. seniors to covid vaccines

SARS-CoV-2 Delta and Delta AY.1 variant show similar Covaxin-induced neutralization

Unvaccinated and vaccinated have similar viral load in communities high in SARS-CoV-2 delta

CHOP researchers identify two proteins that could be used for a potential NTHi vaccine

Intradermal administration of low-dose mRNA COVID-19 vaccine induces strong immune response, study finds

Bus stop by bus stop, Denver-area officials microtarget vaccine hesitancy

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

Latest News