Nephrology News and Research

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Nephrology is a branch of internal medicine and pediatrics dealing with the study of the function and diseases of the kidney.

Cellular and molecular view of intact transparent human organs

For the first time, researchers managed to make intact human organs transparent. Using microscopic imaging they could revealed underlying complex structures of the see-through organs at the cellular level.

13 Feb 2020

A143T variant of the GLA gene likely to cause late-onset Fabry cardiomyopathy

The A143T variant of the GLA gene is associated with an increased risk of Fabry cardiomyopathy, according to a new study.

13 Feb 2020

Study tests hypothesis that empty SV40 capsids would improve sepsis outcomes

Numerous previous attempts to develop therapeutic treatments, directed at discreet targets of the sepsis cascade, could not cope with the complex pathophysiology of sepsis and failed.

13 Feb 2020

Novel drug combination discovered to induce high rates of human beta cell proliferation

Researchers at the Icahn School of Medicine at Mount Sinai have discovered a novel combination of two classes of drugs that, together, cause the highest rate of proliferation ever observed in adult human beta cells- the cells in the pancreas that produce insulin- without harming most other cells in the body.

12 Feb 2020

UC research could help identify organ donors at risk of developing kidney disease

Kidney transplantation is the gold standard treatment for end-stage kidney disease and is associated with an advantage over dialysis in both survival and quality of life.

11 Feb 2020

Combination of two antibiotics found to be no better than one for treating MRSA blood infections

Researchers attempting to improve the treatment for methicillin-resistant Staphylococcus aureus (MRSA) blood infections have discovered the combination of two antibiotics was no better than one, and led to more adverse effects.

11 Feb 2020

Lupus patients who adhere to medications have lower risk of type 2 diabetes

Patients with lupus who take their medications as prescribed have much lower odds of developing type 2 diabetes, a common complication of the disease, finds a new study from the University of British Columbia.

11 Feb 2020

Developmental shape-shifting is key to cancer's ability to spread and evade immune defenses

Just as people tend to become stuck in their ways as they grow older so too do cells. Neurons in the brain don't one day decide to become heart cells; skin cells repair wounds with skin cells rather than kidney cells.

11 Feb 2020

Free radicals from immune cells linked to salt-sensitive hypertension

In salt-sensitive hypertension, immune cells gather in the kidneys and shoot out free radicals, heightening blood pressure and damaging this pair of vital organs, scientists report.

11 Feb 2020

How lifesaving organs for transplant go missing in transit

When a human heart was left behind by mistake on a Southwest Airlines plane in 2018, transplant officials downplayed the incident. They emphasized that the organ was used for valves and tissues, not to save the life of a waiting patient, so the delay was inconsequential.

10 Feb 2020

High bacterial levels in half of lupus skin rashes

A new study published in the Journal of Investigative Dermatology reports that half the skin lesions present in patients with lupus show the presence of viable staph bacteria. This makes them more susceptible to skin infections and also increases the risk that the infection will spread to others.

9 Feb 2020

Smoking cessation goody bag helps people quit smoking

While sitting in the dentist's office, Hollings Cancer Center researcher Matthew Carpenter, Ph.D., of the Medical University of South Carolina, had a bright idea.

9 Feb 2020

Georgia State researcher receives $1.67 million federal grant to study gut immunity

Dr. Tim Denning, professor and associate director of the Institute for Biomedical Sciences at Georgia State University, has received a four-year, $1.67 million federal grant to study how an immunological pathway influences inflammatory signaling in the intestine that can lead to chronic human diseases such as inflammatory bowel disease.

9 Feb 2020

Study lays foundation for translating mitochondrial biology into clinical applications

A study led by The University of Texas MD Anderson Cancer Center furthered understanding about mitochondria, the cell components known as the "powerhouse of the cell." Knowing more about the genome is crucial given that mitochondria play important roles in tumorigenesis.

6 Feb 2020

Preeclamptic women have higher heart disease risk

Women with high blood pressure in their first pregnancy have a greater risk of heart attack or cardiovascular death, according to a Rutgers study.

6 Feb 2020

First comprehensive survey of viruses found within different cancers

Researchers from the University of East Anglia have helped to carry out the first comprehensive survey of viruses found within different types of cancer.

5 Feb 2020

New MR system could help identify pregnant women at high risk of pre-eclampsia

Scientists have developed a new magnetic resonance system which could be used to more effectively identify pregnant women at high-risk of pre-eclampsia.

5 Feb 2020

Researchers develop new substance to prevent vascular calcification

Researchers at ETH Zurich and ETH spin-off Inositec have developed a new substance to prevent vascular calcification, which affects many patients suffering from chronic kidney disease.

5 Feb 2020

New treatment target for acute kidney injury prevention revealed

Up to 10% of patients who are hospitalized or undergo surgery will experience acute kidney injury, and as many as 50% of patients in intensive care units will meet the criteria for AKI, the National Kidney Foundation has determined. Some of these patients will progress to kidney failure within months.

4 Feb 2020

Yale researchers find way to reverse type-2 diabetes and liver fibrosis in mice

In a pair of related studies, a team of Yale researchers has found a way to reverse type-2 diabetes and liver fibrosis in mice and has shown that the underlying processes are conserved in humans.

4 Feb 2020