Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Researchers develop an analytical tool that could lead to lead to noninvasive "liquid biopsies"

Biopsies are clinical tools commonly used to diagnose a variety of diseases or to monitor tissue for abnormal growth or even rejection of a transplant.

17 Jul 2024

UChicago expands microbiome research capabilities with new manufacturing facility

The Duchossois Family Institute (DFI) at the University of Chicago can manufacture clinical-grade encapsulated bacteria – catalyzing opportunities to better understand the microbiome and its myriad of roles in human health.

16 Jul 2024

Mitochondrially-targeted antioxidants could reduce SARS-CoV-2 effects across multiple organs

Building upon groundbreaking research demonstrating how the SARS-CoV-2 virus disrupts mitochondrial function in multiple organs, researchers from Children's Hospital of Philadelphia (CHOP) demonstrated that mitochondrially-targeted antioxidants could reduce the effects of the virus while avoiding viral gene mutation resistance, a strategy that may be useful for treating other viruses.

15 Jul 2024

40% of US cancer cases linked to lifestyle choices

Nearly 40% of cancer cases and 44% of cancer deaths in 2019 were due to modifiable risk factors, with cigarette smoking as the leading cause. This study highlights the potential to significantly reduce cancer burden through lifestyle changes.

14 Jul 2024

WISDOM project leverages AI and data to combat chronic immune-mediated diseases in Europe

Integrating medical and research data, ensuring secure data sharing, and using advanced AI models offer immense possibilities to mitigate the impact of chronic immune-mediated diseases (CIMDs) affecting 10% of Europeans.

12 Jul 2024

Scientists map molecules within human brain for first time

Scientists investigating Alzheimer's disease have determined the structure of molecules within a human brain for the very first time.

12 Jul 2024

Researchers discover a new mechanism of resistance to KRAS inhibitors in pancreas cancer

Mutations in the KRAS gene are the primary driver of pancreatic cancer. A new class of drugs known as KRAS inhibitors is showing initial promise in clinical trials, but many tumors quickly develop resistance to the treatment.

11 Jul 2024

Researchers identify two risk factors that indicate higher risk of aggressive prostate cancer

A recent European Urology Oncology study assessed the mortality risks, based on the Gleason score and clinical parameters, in patients with prostate cancer.

11 Jul 2024

Existing drug shows promise for treating common liver disease

The University of Barcelona has led a study that suggests using the drug known as pemafibrate to treat liver disease associated with metabolic disorders, the most common liver pathology in the world, which affects one in four people. The drug has long been marketed in Japan for another use: improving blood lipid levels in patients with hyperlipidaemia, a common condition in diabetics. Now, however, it could help address this serious liver disease, which still has no specific treatment.

11 Jul 2024

Repurposing pemafibrate to treat liver disease associated with metabolic disorders

10 Jul 2024

Experts identify sex and gender differences in cognitive resistance and resilience to Alzheimer's disease

Researchers investigated sex-related and gender-specific resistance and resilience factors in Alzheimer's disease.

10 Jul 2024

Study highlights hidden aggressiveness in Gleason Grade Group 1 prostate cancer

New research highlights the challenge of balancing the risks of overdiagnosing and underdiagnosing prostate cancer early enough to intervene and minimize risk of death.

9 Jul 2024

Research reveals immune suppression link between cancer and pregnancy

To understand why some cancers successfully circumvent the immune system to grow unchecked, researchers turned to pregnancy.

8 Jul 2024

Case Western Reserve University receives $1.5M grant for oral drug trial to prevent blindness in RP patients

There's only one U.S. Food and Drug Administration-approved therapy for an inherited retinal disease, and dozens of retinitis pigmentosa (RP) genes for which no therapy is available.

8 Jul 2024

AI model revolutionizes dementia diagnosis with high accuracy across multiple data sources

Researchers developed an AI model using multimodal data to accurately diagnose different types of dementia, enhancing early and personalized treatment.

8 Jul 2024

Experts produce consensus statement on sex and gender disparities in resilience to Alzheimer's

An international panel of experts led by the Barcelona Institute for Global Health (ISGlobal), a centre supported by the "la Caixa" Foundation, under the umbrella of the Alzheimer's Association International Society to Advance Alzheimer's Research and Treatment, has produced a consensus statement on sex and gender disparities in resilience to Alzheimer's disease and call for incorporating these differences in future research.

5 Jul 2024

Heparan-sulfate proteoglycans found to influence Alzheimer's cell pathology

The impact of heparan-sulfate-modified proteoglycans (HSPGs) on Alzheimer's disease-associated pathways.

5 Jul 2024

Repurposing cancer drug to prevent organ damage in infectious diseases

Twelve years ago, cancer researchers at University of California San Diego identified a molecule that helps cancer cells survive by shuttling damaging inflammatory cells into tumor tissue.

3 Jul 2024

Machine learning revolutionizes cardiac studies in fruit flies

Drosophila - commonly known as fruit flies - are a valuable model for human heart pathophysiology, including cardiac aging and cardiomyopathy.

3 Jul 2024

Impaired communication between immune cells leads to cognitive impairment in female Alzheimer's patients

Lead author Neta Rosenzweig, PhD, of the Ann Romney Center for Neurological Diseases, and senior author Oleg Butovsky, PhD, of the Ann Romney Center and Gene Lay Institute of Immunology and Inflammation, share key messages from their paper "Sex-Dependent APOE4 Neutrophil-Microglia Interactions Drive Cognitive Impairment in Alzheimer's Disease" published in Nature Medicine.

3 Jul 2024

Pathology News and Research

Further Reading

Researchers develop an analytical tool that could lead to lead to noninvasive "liquid biopsies"

UChicago expands microbiome research capabilities with new manufacturing facility

Mitochondrially-targeted antioxidants could reduce SARS-CoV-2 effects across multiple organs

40% of US cancer cases linked to lifestyle choices

WISDOM project leverages AI and data to combat chronic immune-mediated diseases in Europe

Scientists map molecules within human brain for first time

Researchers discover a new mechanism of resistance to KRAS inhibitors in pancreas cancer

Researchers identify two risk factors that indicate higher risk of aggressive prostate cancer

Existing drug shows promise for treating common liver disease

Repurposing pemafibrate to treat liver disease associated with metabolic disorders

Experts identify sex and gender differences in cognitive resistance and resilience to Alzheimer's disease

Study highlights hidden aggressiveness in Gleason Grade Group 1 prostate cancer

Research reveals immune suppression link between cancer and pregnancy

Case Western Reserve University receives $1.5M grant for oral drug trial to prevent blindness in RP patients

AI model revolutionizes dementia diagnosis with high accuracy across multiple data sources

Experts produce consensus statement on sex and gender disparities in resilience to Alzheimer's

Heparan-sulfate proteoglycans found to influence Alzheimer's cell pathology

Repurposing cancer drug to prevent organ damage in infectious diseases

Machine learning revolutionizes cardiac studies in fruit flies

Impaired communication between immune cells leads to cognitive impairment in female Alzheimer's patients

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