Clinical Trial News and Research

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Early antiretroviral therapy treatment benefits HIV-infected infants

Giving antiretroviral therapy immediately after diagnosis for a limited period of time is more beneficial than postponing treatment in young infants infected with HIV, slowing progression of the disease and delaying the time to starting long-term ART, according to new research published in The Lancet.

23 Aug 2013

Moffitt Cancer Center study could offer hope to melanoma sufferers

A new study at Moffitt Cancer Center could offer hope to people with melanoma, the deadliest form of skin cancer. Researchers are investigating whether an injectable known as PV-10 can shrink tumors and reduce the spread of cancer.

23 Aug 2013

Drug to treat blood cancers may also stop spread of invasive breast cancer

A drug used to treat blood cancers may also stop the spread of invasive breast cancer, researchers at Mayo Clinic in Florida have discovered. Their study, published online in Breast Cancer Research, found that in the lab and in animals, the drug decitabine turns on a gene coding for protein kinase D1 (PRKD1) that halts the ability of cancer cells to separate from a tumor and spread to distant organs.

23 Aug 2013

Caris Life Sciences to facilitate patient access to tumour profiling service in Middle East and Africa

Caris Life Sciences, a leading biosciences company focused on fulfilling the promise of personalized medicine in oncology, has signed a distribution agreement with IPS Genomix to facilitate patient access to its tumour profiling service, Molecular Intelligence, in select Middle Eastern and African markets.

22 Aug 2013

Takeda announces publication of data from two vedolizumab Phase 3 studies for ulcerative colitis and Crohn’s disease

Takeda Pharmaceutical Company Limited today announced that results from two Phase 3 studies evaluating vedolizumab, an investigational humanized monoclonal antibody, for the treatment of adults with moderately to severely active ulcerative colitis and Crohn’s disease, were published in the August 22, 2013 issue of the New England Journal of Medicine.

22 Aug 2013

MicuRx Pharmaceuticals raises $25 million in Series B financing

MicuRx Pharmaceuticals, Inc., a privately-held biopharmaceutical company developing next-generation antibiotics, today announced it raised $25 million in Series B financing. Led by BVCF, a private equity and growth fund specializing in the life sciences industry, the round also includes existing investors Morningside Group and Devon Park Bioventures.

22 Aug 2013

Pazopanib drug shows improved quality of life and safety in metastatic kidney cancer patients

Two oral targeted drugs approved for metastatic kidney cancer worked equally well, but one proved superior in tolerability, according to results of a large international clinical trial led by researchers at Dana-Farber Cancer Institute.

22 Aug 2013

Majority of Alzheimer's researchers support disclosure of results to study participants

A leading group of Alzheimer's researchers contends that, as biomarkers to detect signals of the disease improve at providing clinically meaningful information, researchers will need guidance on how to constructively disclose test results and track how disclosure impacts both patients and the data collected in research studies.

22 Aug 2013

New antibody drug shows positive results for treating Crohn's disease, ulcerative colitis

Vedolizumab, a new intravenous antibody medication, has shown positive results for treating both Crohn's disease and ulcerative colitis, according to researchers at the University of California San Diego, School of Medicine. The findings, published in two papers, will appear in the August 22 issue of the New England Journal of Medicine (NEJM).

22 Aug 2013

Oramed starts patient recruitment in Israel for ORMD-0801 clinical trial for patients with T1DM

Oramed Pharmaceuticals Inc., a developer of oral drug delivery systems, announced today that it has initiated patient recruitment for a new clinical trial of its orally ingestible insulin capsule, ORMD-0801 for patients with type 1 diabetes mellitus in Israel.

22 Aug 2013

Radiation Oncologist receives Young Investigator Award from PCF

Jefferson Radiation Oncologist, Nicole Simone, M.D., was recently awarded one of 21 Young Investigator Awards from the Prostate Cancer Foundation (PCF).

21 Aug 2013

NIH awards grant to FDA-approved clinical trial of auditory brainstem implant in children

House Research Institute (HRI) and Children's Hospital Los Angeles Children's Hospital) announced today final approval of grant funding by the National Institutes of Health (NIH) National Institute on Deafness and Communications Disorders (NIDCD) for a major five-year, FDA-approved clinical trial of the auditory brainstem implant (ABI) in children.

21 Aug 2013

Study shows continuous CSF drainage is associated with complications in patients with SAH

Researchers at Duke University conducted a randomized clinical trial in patients with subarachnoid hemorrhage (SAH). In this study, the researchers compared two approaches to intracranial pressure management-continuous and intermittent drainage of cerebrospinal fluid (CSF)-and outcomes associated with those methods, focusing specifically on the incidence of cerebral vasospasm.

21 Aug 2013

Researchers develop simple scoring system to predict risk of dementia in older diabetes patients

Researchers have developed a simple scoring system, based on a patient’s age, health issues, and education, which accurately predicts the risk of dementia in people aged over 60 with type 2 diabetes.

20 Aug 2013

Acne and diet: an interview with Dr Katerina Steventon, Research Fellow, HONEI, University of Hull

The typical Western diet tends to have a high glycemic index. High glycemic index foods are e.g. white bread, processed cereals, snacks, cakes and deserts, sweets and also instant foods like burgers and fried chicken.

20 Aug 2013

Researchers find new strategy that has potential to change standard of care for DLBCL patients

Patients with an aggressive lymphoma that often relapses and kills within two years experienced a remission of their cancer and stayed disease-free as long as 28 months after taking a commercially-available drug that made chemotherapy more effective.

20 Aug 2013

Phase III trial evaluates impact of Wisconsin Ginseng on fatigue levels of cancer patients

Millions of cancer patients find themselves exhausted completing the most mundane of tasks, and extra sleep doesn't seem to help. Today, they find hope in a supplement that medical researchers have shown to be effective in boosting their energy levels: Wisconsin Ginseng.

20 Aug 2013

New data analyzing technique via MR imaging identify tumors' response to anti-angiogenesis therapy

A new way of analyzing data acquired in MR imaging appears to be able to identify whether or not tumors are responding to anti-angiogenesis therapy, information that can help physicians determine the most appropriate treatments and discontinue ones that are ineffective.

20 Aug 2013

Clinical trial shows type-1 diabetes patients treated with teplizumab exhibit greater response to therapy

Primary results from a new clinical trial show that patients with type 1 diabetes treated with the monoclonal antibody teplizumab (MacroGenics, Inc.) exhibit greater preservation of C-peptide, a biomarker of islet cell function, compared to controls.

20 Aug 2013

KCI launches new app to help physicians become aware of cutting-edge cancer clinical trials

The Barbara Ann Karmanos Cancer Institute (KCI) today announced its new app to help physicians and healthcare professionals become aware of cutting-edge cancer clinical trials, often available only at Karmanos. The KCI Trials App is free and available on the App Store(SM) for the iPhone and iPad.

19 Aug 2013

Clinical Trial News and Research

Early antiretroviral therapy treatment benefits HIV-infected infants

Moffitt Cancer Center study could offer hope to melanoma sufferers

Drug to treat blood cancers may also stop spread of invasive breast cancer

Caris Life Sciences to facilitate patient access to tumour profiling service in Middle East and Africa

Takeda announces publication of data from two vedolizumab Phase 3 studies for ulcerative colitis and Crohn’s disease

MicuRx Pharmaceuticals raises $25 million in Series B financing

Pazopanib drug shows improved quality of life and safety in metastatic kidney cancer patients

Majority of Alzheimer's researchers support disclosure of results to study participants

New antibody drug shows positive results for treating Crohn's disease, ulcerative colitis

Oramed starts patient recruitment in Israel for ORMD-0801 clinical trial for patients with T1DM

Radiation Oncologist receives Young Investigator Award from PCF

NIH awards grant to FDA-approved clinical trial of auditory brainstem implant in children

Study shows continuous CSF drainage is associated with complications in patients with SAH

Researchers develop simple scoring system to predict risk of dementia in older diabetes patients

Acne and diet: an interview with Dr Katerina Steventon, Research Fellow, HONEI, University of Hull

Researchers find new strategy that has potential to change standard of care for DLBCL patients

Phase III trial evaluates impact of Wisconsin Ginseng on fatigue levels of cancer patients

New data analyzing technique via MR imaging identify tumors' response to anti-angiogenesis therapy

Clinical trial shows type-1 diabetes patients treated with teplizumab exhibit greater response to therapy

KCI launches new app to help physicians become aware of cutting-edge cancer clinical trials

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