Kidney News and Research

RSS

Distributing medications in specially designed blister packages rather than in bottles may increase the likelihood that medications will be taken properly

The study found that patients taking lisinopril – a medication used to treat chronic high blood pressure – were more likely to have their prescriptions refilled on time if the medication came in a blister package rather than as loose tablets in a bottle. In this case, the blister package clearly started the day on which to take each pill.

16 May 2005

Unsuspected protein CD147, regulates the production of plaque-forming peptides that are the defining feature of Alzheimer's

Researchers at the Department of Energy's Lawrence Berkeley National Laboratory have discovered an unsuspected subunit of the protein complex gamma-secretase, which plays a central role in Alzheimer's disease.

15 May 2005

New anticancer drug SU11248 shows continued response for patients with late-stage kidney cancer

Recent studies of a new anticancer drug show continued response for patients with late-stage kidney cancer. Robert Motzer, MD, attending physician at Memorial Sloan-Kettering Cancer Center (MSKCC), reported a response rate of 40 percent in patients with metastatic (advanced) renal cell (kidney) cancer who received SU11248 in second-line therapy.

15 May 2005

Research proves the dangers of salt

Sydney University scientists have proved that salt has a dangerous adrenalin-inducing effect on people suffering from high blood pressure, or 'hypertension'.

10 May 2005

Metabolic syndrome costing four times that for all other patients

It is well known that hypertension, diabetes, and obesity are each taking a toll on Americans' health, but according to a new analysis, metabolic syndrome, a condition characterized by a combination of these and/or other risk factors, is fast becoming one of the nation's costliest health concerns.

9 May 2005

Chronic kidney disease linked to a single gene mutation

New research in the US has found that a mutation in a single gene causes a form of chronic kidney disease.

5 May 2005

Nephrogenic Syndrome of Inappropriate Antidiuresis - a new genetic disease

Two infant boys whose bodies were overloaded with excess fluid have led UCSF pediatricians to the discovery of a new genetic disease. In the process, they have discovered a rare type of mutation where different substitutions in a single amino acid cause two different, opposite genetic disorders.

4 May 2005

Pharmacogenomics used to treat inherited kidney disorder of children

Mayo Clinic researchers have used pharmacogenomics to develop a test and treatment for an inherited kidney disorder that can cause organ failure in children and young adults.

4 May 2005

Specific variants of genes predict bleeding after heart surgery

Duke University Medical Center researchers have found that the presence of specific variants of genes that control clotting and the contractility, or "tone," of blood vessels can double the ability of physicians to predict those heart surgery patients at greatest risk of bleeding after surgery.

4 May 2005

Diabetes appears to rob women of usual advantage in heart disease risk

For men, a heart attack increases the risk of dying from coronary heart disease more than diabetes does, but for women, diabetes is sometimes the greater threat, according to a new study (PDF) in the May 3, 2005, issue of the Journal of the American College of Cardiology.

4 May 2005

Scientists dramatically slow organ transplant rejection

That's the promising implication of an animal study carried out by researchers at the University of Alabama at Birmingham (UAB) and the University of Florida (UF) published in today's (May 2) issue of Proceedings of the National Academy of Sciences.

3 May 2005

Age-related macular degeneration is triggered, possibly by an infection

Age-related macular degeneration, the leading cause of blindness in the elderly, occurs when a common inherited gene variation is triggered, possibly by an infection, according to a new study led by researchers at Columbia University Medical Center and the University of Iowa, with an international research team.

1 May 2005

Potential for brain stem cells to be used to cure diabetes

Promising new research by US scientists has shown the potential for brain stem cells to be used to cure diabetes. The work by Stanford University researchers, though not yet ready to be tested on human patients, has shown promising results in animals.

28 Apr 2005

New guidelines for managing chronic kidney disease in patients living with HIV infection

The HIV Medicine Association has released guidelines for managing chronic kidney disease in patients living with HIV infection. They are published in the June 1 issue of Clinical Infectious Diseases.

27 Apr 2005

Scientists add an important piece to the intricate puzzle of type-1 diabetes

For some time, scientists have known that a regenerative or repair process -- involving the development of specialized structures called tubular complexes -- is switched on during physical and chemical trauma to the pancreas (the gland that manufactures and secretes crucial insulin in the body).

27 Apr 2005

National clinical trial examines new option for kidney cancer patients

The trial, which opened last September, offers research subjects who qualify a new, targeted therapy in addition to standard immune therapy. The drug combination is being studied in a national Phase II clinical trial led by OHSU Cancer Institute researcher Christopher Ryan, M.D., through the Southwest Oncology Group, one of the largest clinical trial cooperative groups in the United States.

27 Apr 2005

Hereditary colorectal cancer risk lowered in those without certain gene defect

Families with a certain type of hereditary colorectal cancer have a reduced cancer risk if they do not have a gene defect found in many with this type of cancer risk, according to a study in the April 27 issue of JAMA.

26 Apr 2005

Patient with rare liver condition second ever to survive liver transplant after pregnancy

For Billi Tierney, 30, National Donate Life Month in April has a profound meaning. The first-time mother of Sycamore, Ill., was awaiting anxiously the arrival of her first baby. But she never thought that complications from her pregnancy were going to lead to a week in coma and the urgent need for a liver transplant. Tierney suffered from acute liver fatty of pregnancy, a rare, but serious condition of pregnancy in which there is an excessive accumulation of fat in the liver or liver cells.

23 Apr 2005

Obesity sends Type 2 diabetes rates in children soaring

Research results revealed at the Diabetes UK Annual Professional Conference, show 22 children under 16 have Type 2 diabetes in East London alone. Past estimates suggest there were only around 100 children diagnosed with Type 2 diabetes in the UK but this figure now appears to be a vast underestimate.

23 Apr 2005

Brain system that controls the sleep/wake cycle might also play a role in regulating appetite and metabolism

A new mouse study suggests that a brain system that controls the sleep/wake cycle might also play a role in regulating appetite and metabolism. Mice with a mutation in a gene called "Clock," which helps drive circadian rhythm, ate significantly more and gained more weight.

22 Apr 2005