Metabolite News and Research

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Metabolites are the intermediates and products of metabolism. The term ''metabolite'' is usually restricted to small molecules.

Discovery of metabolite linked to aggressive prostate cancer

Researchers from the University of Michigan Comprehensive Cancer Center have identified a panel of small molecules, or metabolites, that appear to indicate aggressive prostate cancer.

15 Feb 2009

Compound can distinguish between benign tissue and localized and metastatic prostate cancer

Researchers have determined that a molecule produced by the bodys metabolism could be used to differentiate between benign prostate tissue vs. localized and metastatic prostate cancer.

11 Feb 2009

MR spectroscopy may help avoid invasive procedures and treatments for recurrent brain lesions

A clinical decision model which uses MR spectroscopy to help physicians differentiate between recurrent tumors and changes in the brain tissue due to radiation treatments, may help patients avoid invasive procedures and treatments, according to a study performed at the University of Michigan Health System in Ann Arbor, MI.

2 Feb 2009

Although our genetics differ significantly, we all look alike...

The genetic variation within a species can be significant, but very little of that variation results in clear differences in morphology or other phenotypes.

27 Jan 2009

MRI scans emerge as vital resource in treatment of back pain

Magnetic resonance imaging (MRI) is a growing technology providing an increasing number of clinical benefits when used in the evaluation of back pain according to an article in the January 2009 issue of the Journal of the American Academy of Orthopaedic Surgeons.

5 Jan 2009

Magnetic resonance imaging emerges as vital resource in back pain treatment

1 Jan 2009

Drinkers with the ADH1C gene at greater risk of colorectal cancer

Chronic drinking is a risk factor for colorectal cancer, possibly through the effects of acetaldehyde, which is created by the alcohol dehydrogenase (ADH) enzyme.

21 Dec 2008

SRS microscopy helps track molecules and drugs in live cells

A new type of highly sensitive microscopy developed by researchers at Harvard University could greatly expand the limits of modern biomedical imaging, allowing scientists to track the location of minuscule metabolites and drugs in living cells and tissues without the use of any kind of fluorescent labeling.

18 Dec 2008

Breakthrough on type 1 diabetes development

Finnish scientists have reported a breakthrough in the attempts to understand the development of type 1 diabetes.

17 Dec 2008

Researchers create new family of fluorescent probes called hydrocyanines to detect reactive oxygen species in vivo

Researchers have created a new family of fluorescent probes called hydrocyanines that can be used to detect and measure the presence of reactive oxygen species.

15 Dec 2008

Researchers find tamoxifen's power comes from endoxifen

Mayo Clinic researchers have discovered that a chemical known as endoxifen appears to be the primary metabolite responsible for the effectiveness of tamoxifen in treating breast cancer, and that it works against cancer in an entirely unexpected way.

12 Dec 2008

New class of anti-inflammatory drugs

In the treatment of pain, inflammation and fever, non-steroid anti-rheumatic drugs (NSAR) such as acetylsalicylic acid - more commonly known as Aspirin - or Ibuprofen have always been popular choices.

10 Dec 2008

Environmental tobacco smoke linked to behavioral problems in boys with asthma

Boys with asthma who are exposed to environmental tobacco smoke have higher degrees of hyperactivity, aggression, depression and other behavioral problems, according to researchers at Cincinnati Children's Hospital Medical Center.

5 Dec 2008

More evidence on why the Mediterranean diet is good for heart

Researchers have discovered one potential mechanism by which briefly cutting off, then restoring, blood flow to arteries prior to a heart attack lessens the damage caused, according to a study published today in the journal Cardiovascular Research.

2 Dec 2008

Babies exposed to tobacco in utero more irritable, difficult to soothe

Previous studies have shown that babies exposed to tobacco in utero are more likely to have a low birth weight and are at increased risk for sudden infant death syndrome.

1 Dec 2008

Genetic variation in metabolism identified

Metabolic diseases - in particular the increasingly prevalent type 2 diabetes - are caused by a complex interaction between genetic disposition and unfavorable lifestyle, above all unbalanced diet and too little physical exercise.

30 Nov 2008

Study identifies genetic variants giving rise to differences in metabolism

Common genetic polymorphisms induce major differentiations in the metabolic make-up of the human population, according to a paper published November 28 in the open-access journal PLoS Genetics.

28 Nov 2008

Researchers discover that a lipid produced in the gut rises after eating fatty foods

As you gorge on food this holiday season, you might not want to think about the fat content of all the goodies you've indulged in.

26 Nov 2008

Novel device enhances efficacy of standard chemotherapy

NovoCure Ltd. presented results yesterday evaluating the Novo-TTF device in vitro and in a pilot clinical trial that showed the device enhanced the efficacy of standard chemotherapy (temozolomide) treatment in newly-diagnosed glioblastoma multiforme (GBM) patients.

24 Nov 2008

Smoking when pregnant doubles risk of cleft palate or lip in babies

Babies whose mothers smoked during pregnancy were more than twice as likely to have a cleft palate or lip as those whose mothers didn't, according to research results released today.

6 Nov 2008