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Restoring brain energy balance reverses Alzheimer’s disease in mouse models

For over a century, Alzheimer's disease (AD) has been considered irreversible. Consequently, research has focused on disease prevention or slowing, rather than recovery.

23 Dec 2025

AI analysis maps a century of global aging research

A new research paper was published in Volume 17, Issue 11 of Aging-US on November 25, 2025, titled "A natural language processing–driven map of the aging research landscape."

23 Dec 2025

Prebiotic microcapsules deliver pterostilbene to the colon to alleviate ulcerative colitis

A team led by clinicians and engineers has wrapped the plant-derived polyphenol pterostilbene (PSB) into prebiotic alginate/resistant-starch microcapsules coated with chitosan and shown that oral administration dampens dextran-sulfate-sodium (DSS) colitis in mice.

23 Dec 2025

Wearable AI device detects early signs of frailty in older adults

University of Arizona researchers in the Gutruf Lab have developed a comfortable, easy-to-use wearable device that incorporates artificial intelligence to detect subtle warning signs of frailty, signifying a leap forward in elderly care.

22 Dec 2025

Altered stress signaling helps explain relapse in alcohol use disorder

A new study by Scripps Research reveals that alcohol dependence disrupts two signaling pathways in a stress-related part of the brain-and offers insights on developing drugs to treat this condition.

22 Dec 2025

Cells balance protein production and removal through passive adaptation

Every cell depends on proteins to function and stay healthy. These proteins are made inside the cell from amino acids but cannot simply accumulate inside the cell forever.

22 Dec 2025

Fatty diets reprogram hepatocytes and increase liver cancer risk

One of the biggest risk factors for developing liver cancer is a high-fat diet. A new study from MIT reveals how a fatty diet rewires liver cells and makes them more prone to becoming cancerous.

22 Dec 2025

Popular video games may offer meaningful emotional benefits for young adults

Blood metabolite profiling outperforms BMI in predicting pregnancy complications

This study shows that a blood-based metabolomic signature linked to maternal BMI predicts gestational diabetes and preeclampsia more strongly than BMI alone, particularly in late pregnancy. A subset of 16 metabolites statistically mediates the BMI–gestational diabetes association, highlighting metabolic pathways that may improve prenatal risk stratification.

21 Dec 2025

New CPRIT awards expand cancer prevention and treatment research in South Texas

UT Health San Antonio, the academic health center of The University of Texas at San Antonio (UT San Antonio), received nearly $3 million in new academic and prevention awards as part of the latest funding round announced by the Cancer Prevention Research Institute of Texas (CPRIT).

19 Dec 2025

Prenatal exposure to hot and humid conditions worsens child growth outcomes

The dangers of heat and humidity are so well known it's become cliche to mention them. But the impacts can extend farther than even scientists and doctors realized.

19 Dec 2025

Guns marketed for personal safety fuel public health crisis in Black communities

Leon Harris, 35, is intimately familiar with the devastation guns can inflict. Robbers shot him in the back nearly two decades ago, leaving him paralyzed from the chest down. The bullet remains lodged in his spine.

19 Dec 2025

Financial strain and food insecurity drive accelerated cardiac aging

A novel analysis investigating the contribution of social determinants of health (SDoH) to cardiac aging has found that financial strain and food insecurity are the strongest drivers of accelerated biological aging and increased mortality risk.

18 Dec 2025

Researchers point to mitochondria as a missing link between mental health and brain function

A stressful year leads to anxiety. Lasting isolation gives way to depression. An old trauma nags until it becomes paralyzing.

18 Dec 2025

Study finds Brain Care Score as a strong predictor of stroke across racial groups

A new study from Mass General Brigham found the Brain Care Score (BCS) is a strong predictor of stroke across different racial groups in the U.S.

18 Dec 2025

Scientists unravel how citrin deficiency can trigger fat buildup in the liver even in lean individuals

Scientists at City of Hope, one of the largest and most advanced cancer research and treatment organizations in the U.S. and a leading research center for diabetes and other life-threatening illnesses, have unraveled how citrin deficiency (CD), a rare genetic disorder that prevents the liver from converting food into energy efficiently, can trigger fat buildup in the liver - even in lean individuals.

18 Dec 2025