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Innovative nebulizer to treat cystic fibrosis developed by Cambridge Consultants

Observing surfers with cystic fibrosis (CF) led scientists to discover that the inhaled mist of seawater has a therapeutic effect on the lung problems associated with the disease. Now the findings have been used by pharmaceutical company Parion Sciences and product development firm Cambridge Consultants in a revolutionary new aerosol delivery system. It enables CF sufferers to get the benefits of saltwater treatment in their own homes overnight while they sleep.

23 May 2013

REPRISE II trial: Lotus Valve System meets primary endpoint in severe aortic valve disease patients

Boston Scientific Corporation reports positive results from a pre-specified analysis of the first 60 patients enrolled in the REPRISE II trial evaluating the performance and safety of the Lotus™ Valve System in symptomatic patients with severe aortic valve disease considered at high risk for surgical valve replacement.

23 May 2013

Cognoptix' SAPPHIRE II eye test identifies Alzheimer's disease patients via Ab signature in the eyes

Cognoptix, an emerging medical device company, announced today that its SAPPHIRE II eye test identified Alzheimer's disease patients via a beta amyloid ("Ab") signature in their eyes in a 10-subject proof-of-concept clinical trial.

23 May 2013

$Upsher-Smith completes USL255 Phase III clinical trial in patients with refractory POS$

Upsher-Smith completes USL255 Phase III clinical trial in patients with refractory POS

Upsher-Smith Laboratories, Inc. today announced the successful completion of its global Phase III clinical trial for USL255 (extended-release topiramate), an internally developed program for the management of epilepsy in adults, using the company's proprietary formulation technology.

23 May 2013

A1-PI treatment slows progression of emphysema in patients with AATD

Treatment with an Alpha-1 proteinase inhibitor (A1-PI), a naturally occurring protein that protects lung tissue from breakdown and protects the lung's elasticity, is effective in slowing the progression of emphysema in patients with Alpha-1 antitrypsin deficiency (AATD), a life-threatening genetic disorder, according to a new study presented at the 2013 American Thoracic Society International Conference.

22 May 2013

Boehringer Ingelheim's tiotropium shows promising results in patients with severe persistent asthma

Boehringer Ingelheim today announced data from Phase 2 and Phase 3 studies from the Company's ongoing clinical trial program investigating the efficacy and safety of tiotropium in asthma. These data were presented at the American Thoracic Society International Conference in Philadelphia, Pennsylvania.

22 May 2013

Obesity directly tied to several cancers

"Obesity is a major risk factor for developing cancer, roughly the equivalent of tobacco use, and both are potentially reversible. Further, obese cancer patients do worse in surgery, with radiation or on chemotherapy - worse by any measure." Karen Basen-Engquist, Ph.D., Director of MD Anderson's new Center for Energy Balance in Cancer Prevention and Survivorship and professor of Behavioral Science.

22 May 2013

Ongoing clinical study to evaluate benefits of high-dose simvastatin for patients with SAH

Can treatment with high doses of a cholesterol-lowering statin drug improve outcomes for patients with stroke caused by rupture and bleeding of brain aneurysms? An ongoing clinical trial will soon find out, according to an article in the May issue of Neurosurgery, official journal of the Congress of Neurological Surgeons.

22 May 2013

Studies show that LipiGesic M provides highly effective OTC solution to migraine pain

PuraMed BioScience, Inc., a researcher, developer, and marketer of over-the-counter medicinal and healthcare products, announced the results of clinical trials that found its over-the-counter migraine medication product, LipiGesic M, has "robust efficacy".

22 May 2013

AIR2 trial: Alair BT System shows therapy benefits in adults with severe uncontrolled asthma

Five-year data from the Asthma Intervention Research 2 clinical trial presented today demonstrated that the Boston Scientific Corporation Alair Bronchial Thermoplasty System continues to show therapy benefits in adult patients with severe uncontrolled asthma.

22 May 2013

Environmental enrichment therapy improves behaviors of children with autism

Children with autism showed significant improvement after six months of simple sensory exercises at home using everyday items such as scents, spoons and sponges, according to UC Irvine neurobiologists.

22 May 2013

Vitamin C kills drug-resistant TB bacteria in lab

In a striking, unexpected discovery, researchers at Albert Einstein College of Medicine of Yeshiva University have determined that vitamin C kills drug-resistant tuberculosis bacteria in laboratory culture.

22 May 2013

Study: Use of bronchodilators linked with increased risks of cardiovascular events

A study of older patients with chronic obstructive pulmonary disease (COPD) suggests that new use of the long-acting bronchodilators β-agonists and anticholinergics was associated with similar increased risks of cardiovascular events, according to a study published Online First by JAMA Internal Medicine, a JAMA Network publication.

21 May 2013

Clinical trial of Echo Therapeutics' Symphony CGM System receives IRB approval

Echo Therapeutics, Inc., a company developing its needle-free Symphony CGM System as a non-invasive, wireless, transdermal continuous glucose monitoring system, announced today that the Company's clinical trial of its Symphony CGM System has received Institutional Review Board approval.

21 May 2013

TB clinical drug trials in jeopardy due to federal sequestration funding cuts

Innovative and potentially game-changing clinical trials to develop new drug regimens to prevent and treat tuberculosis, the second leading global infectious disease killer, are in jeopardy due to federal "sequestration" funding cuts.

21 May 2013

New research suggests that listening to music lowers anxiety, sedation in ventilated patients

New research suggests that for some hospitalized ICU patients on mechanical ventilators, using headphones to listen to their favorite types of music could lower anxiety and reduce their need for sedative medications.

21 May 2013

Study suggests that fluid, sodium restrictions have no effect on weight loss in ADHF patients

A clinical trial of 75 patients hospitalized with acute decompensated heart failure suggests that aggressive fluid and sodium restriction has no effect on weight loss or clinical stability at three days but was associated with an increase in perceived thirst, according to a study published Online First by JAMA Internal Medicine, a JAMA Network publication.

21 May 2013

XenoPort's Arbaclofen placarbil fails to meet co-primary endpoints in Phase 3 clinical trial

XenoPort, Inc. announced today top-line results from its pivotal Phase 3 clinical trial of arbaclofen placarbil for the treatment of patients with spasticity due to multiple sclerosis.

20 May 2013

Cell Therapeutics announces issuance of final benefit assessment report for PIXUVRI

Cell Therapeutics, Inc. today reported that Germany's Federal Joint Committee has issued its final benefit assessment report for PIXUVRI (pixantrone), which is indicated as a monotherapy for the treatment of adult patients with aggressive B-cell non-Hodgkin lymphoma (NHL) who have failed two or three prior lines of therapy.

20 May 2013

Joint replacement surgery might be avoidable in the future, suggest scientists

Scientists at Johns Hopkins have turned their view of osteoarthritis inside out. Literally. Instead of seeing the painful degenerative disease as a problem primarily of the cartilage that cushions joints, they now have evidence that the bone underneath the cartilage is also a key player and exacerbates the damage.

20 May 2013

Clinical Trial News and Research

Innovative nebulizer to treat cystic fibrosis developed by Cambridge Consultants

REPRISE II trial: Lotus Valve System meets primary endpoint in severe aortic valve disease patients

Cognoptix' SAPPHIRE II eye test identifies Alzheimer's disease patients via Ab signature in the eyes

Upsher-Smith completes USL255 Phase III clinical trial in patients with refractory POS

A1-PI treatment slows progression of emphysema in patients with AATD

Boehringer Ingelheim's tiotropium shows promising results in patients with severe persistent asthma

Obesity directly tied to several cancers

Ongoing clinical study to evaluate benefits of high-dose simvastatin for patients with SAH

Studies show that LipiGesic M provides highly effective OTC solution to migraine pain

AIR2 trial: Alair BT System shows therapy benefits in adults with severe uncontrolled asthma

Environmental enrichment therapy improves behaviors of children with autism

Vitamin C kills drug-resistant TB bacteria in lab

Study: Use of bronchodilators linked with increased risks of cardiovascular events

Clinical trial of Echo Therapeutics' Symphony CGM System receives IRB approval

TB clinical drug trials in jeopardy due to federal sequestration funding cuts

New research suggests that listening to music lowers anxiety, sedation in ventilated patients

Study suggests that fluid, sodium restrictions have no effect on weight loss in ADHF patients

XenoPort's Arbaclofen placarbil fails to meet co-primary endpoints in Phase 3 clinical trial

Cell Therapeutics announces issuance of final benefit assessment report for PIXUVRI

Joint replacement surgery might be avoidable in the future, suggest scientists

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