Abdominal Pain News and Research

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Abdominal pain is traditionally described by its chronicity (acute or chronic), its progression over time, its nature (sharp, dull, colicky), its distribution (by various methods, such as abdominal quadrant (left upper quadrant, left lower quadrant, right upper quadrant, right lower quadrant) or other methods that divide the abdomen into nine sections), and by characterization of the factors that make it worse, or alleviate it.

IgG-guided diet outperforms sham diet in clinical trial

Michigan Medicine and Cleveland Clinic researchers have found that patients with irritable bowel syndrome were more likely to experience less abdominal pain if they followed a diet guided by the results of a blood test, compared to those who followed a sham elimination diet.

13 Feb 2025

Opioid δ-receptor agonists show promise for treating IBS-like symptoms

Research reveals that δ-receptor agonists like KNT-127 alleviate IBS symptoms by modulating gut-brain interactions and reducing stress-induced hypermotility.

7 Feb 2025

New drug class may help alleviate IBS symptoms by targeting the central nervous system

Irritable bowel syndrome (IBS) is a common digestive disorder that affects the intestine, causing symptoms such as abdominal pain, bloating, gas, and changes in bowel habits, including diarrhea, constipation, or both.

5 Feb 2025

Study highlights delayed cancer diagnoses in pregnant women

Cancer symptoms can sometimes be misdiagnosed as normal pregnancy-related changes for women who are expecting, in some cases leading to a delay in treatment, according to a new study from the University of Surrey.

30 Jan 2025

Research highlights differences in how hospitals diagnose appendicitis in children

Abdominal pain is among the most common reasons children are taken to the emergency department.

29 Jan 2025

Triple therapy shows strong response in BRAF V600E mutant metastatic colorectal cancer

Patients with metastatic colorectal cancer (mCRC) harboring BRAF V600E mutations benefitted from first-line treatment with the targeted therapies encorafenib and cetuximab plus a mFOLFOX6 chemotherapy regimen, according to results from the Phase III BREAKWATER trial led by researchers at The University of Texas MD Anderson Cancer Center.

26 Jan 2025

Researchers create an atlas of health associations for GLP-1 receptor agonists

Insights from a study on GLP-1 receptor agonists reveal benefits for cardiometabolic health, with notable risks for gastrointestinal and musculoskeletal issues.

20 Jan 2025

Inflammation in the gut could explain gastrointestinal problems in psoriasis patients

People with the skin condition psoriasis often have invisible inflammation in the small intestine with an increased propensity for 'leaky gut', according to new research at Uppsala University.

20 Jan 2025

Study uncovers key role of NSP4 in rotavirus disease severity

Researchers at Baylor College of Medicine and collaborating institutions have improved our understanding of how rotavirus, the most common cause of acute gastroenteritis in children, makes people sick.

17 Jan 2025

ED physicians’ admission rates do not translate to better patient health outcomes

Patients in emergency departments who are treated by physicians with a high propensity to admit those they see into the hospital are more likely to be discharged after only a short stay, suggesting a possible unnecessary admission, while they are no less likely to die, new research suggests.

23 Dec 2024

LLMs show potential as aids for clinicians during physical exams

Physical examinations are important diagnostic tools that can reveal critical insights into a patient's health, but complex conditions may be overlooked if a clinician lacks specialized training in that area.

19 Dec 2024

Nutraceuticals: exploring potential benefits and challenges of an unregulated healthcare frontier

Nutraceuticals offer potential health benefits, from migraine relief to cognitive support, but safety and regulatory issues must be addressed for effective use.

18 Dec 2024

New study uncovers role of amino acid serine in preventing food poisoning

Food poisoning is a common, yet unpleasant, illness caused by eating contaminated items. It is sometimes caused by Clostridium perfringens, a pathogen widely found in soil and the intestinal tracts of animals.

12 Dec 2024

Study highlights global surge in early-onset colorectal cancer

A new study led by American Cancer Society (ACS) researchers shows that early-onset colorectal cancer (CRC) incidence rates are rising in 27 of 50 countries/territories worldwide, 20 of which have either exclusive or faster increases for early-onset disease.

11 Dec 2024

Mediterranean diet linked to reduced risk of inflammatory bowel disease

Research suggests the Mediterranean diet supports inflammatory bowel disease management, enhancing gut microbiota with nutrients like omega-3 fatty acids.

10 Dec 2024

Filgotinib offers new promise for managing Crohn’s disease

Filgotinib, a JAK1 preferential inhibitor, shows promise as an effective and well-tolerated maintenance therapy for Crohn's disease, achieving clinical and endoscopic remission in phase 3 trials. The findings highlight its potential as a novel therapeutic option for difficult-to-treat patients.

8 Dec 2024

$1.5 million grant supports alternatives to opioids initiative at University Hospitals

A grant of nearly $1.5 million from the Department of Health and Human Services through its Substance Abuse and Mental Health Services Administration (SAMHSA) will enable University Hospitals Cleveland Medical Center to develop and implement an Alternatives to Opioids (ALTO) program within its Emergency Department (ED).

6 Dec 2024