Allele News and Research

RSS

Ultra-rare gene variants drive coronary artery disease risk in European ancestry

Researchers found that ultra-rare genetic variants play a significant role in the heritability of coronary artery disease (CAD), particularly in individuals of European ancestry. These variants, especially those altering proteins or regulating genes in heart cells, pose higher risks than common variants.

13 Oct 2024

Study highlights the role of genetic factors in COVID-19 thrombosis and inflammation

Despite global vaccination efforts, COVID-19 continues to pose significant risks, leading to severe complications and fatalities. These risks are driven by disrupted coagulation, impaired fibrinolysis, which is the process of breaking blood clots, and heightened inflammatory responses.

3 Oct 2024

Genetic study uncovers key drivers of metabolic syndrome with brain tissue links

Researchers uncovered 1,307 genetic loci linked to metabolic syndrome, revealing brain tissue enrichment and key genetic factors in its development. The study also shows polygenic risk scores predict metabolic syndrome across populations.

1 Oct 2024

Liver receptor mutations linked to liver dysfunction, cholesterol accumulation, and hepatitis

Damaging LXRα variants are linked to liver cholesterol buildup and hepatitis, emphasizing the receptor's importance in cholesterol sensing and liver function.

27 Sep 2024

A faster, cheaper method to detect immune autoantibodies in whole blood

Researchers developed a quick and affordable whole-blood assay to detect autoantibodies against type I IFNs, enabling rapid diagnostics for immune disorders. This new method has potential clinical impact by addressing key limitations of current tests.

25 Sep 2024

Cardiovascular disease pathways associated with psoriasis, but not other immune-mediated diseases

A genetic connection between cardiovascular disease and psoriasis highlights shared inflammatory pathways, emphasizing the need for cardiovascular monitoring.

19 Sep 2024

Unraveling psychiatric disorders with cutting-edge epigenetic tools

The "Innovators & Ideas: Rising Star" section of Genomic Psychiatry features an illuminating "Genomic Press Interview" with Dr. Pierre-Eric Lutz, a rising star in the field of neuro-epigenetics.

5 Sep 2024

Clonal hematopoiesis drives femoral atherosclerosis in middle-aged adults

Researchers reveal that clonal hematopoiesis (CH) significantly increases the risk of developing femoral atherosclerosis, suggesting a unidirectional relationship independent of traditional cardiovascular risk factors.

2 Sep 2024

Amyloid immunotherapy for early Alzheimer's: Promising but fraught with challenges

Researchers highlighted the complexities of using amyloid immunotherapy for early Alzheimer's disease, discussing its clinical benefits, challenges, and broader health implications. Despite some positive results, concerns over adverse effects, trial biases, and cost hinder widespread adoption.

7 Aug 2024

Omega-3 fatty acids show potential in protecting brain health in older adults

Researchers assess the role of ω-3 polyunsaturated fatty acids (PUFAs) in reducing white matter lesion accumulation and neuronal integrity degeneration.

6 Aug 2024

Living near greenspace in midlife tied to slower cognitive decline in older age

The association between midlife residential greenness and cognitive decline.

22 Jul 2024

New study reveals the genetic cause of Parkinson's disease

According to Science Alert, neuroscientists from Johns Hopkins University have recently discovered a new treatment for Parkinson's disease using an FDA-approved cancer drug.

11 Jul 2024

Novel Co-STAR cells show promise in targeting and eradicating cancer

Using genetic engineering techniques, investigators at the Johns Hopkins Kimmel Cancer Center and its Ludwig Center, the Lustgarten Laboratory and Bloomberg~Kimmel Institute for Cancer Immunotherapy have designed a novel type of cell to recognize and fight cancer.

11 Jul 2024

Allele News and Research

Ultra-rare gene variants drive coronary artery disease risk in European ancestry

Study highlights the role of genetic factors in COVID-19 thrombosis and inflammation

Genetic study uncovers key drivers of metabolic syndrome with brain tissue links

Liver receptor mutations linked to liver dysfunction, cholesterol accumulation, and hepatitis

A faster, cheaper method to detect immune autoantibodies in whole blood

Cardiovascular disease pathways associated with psoriasis, but not other immune-mediated diseases

Unraveling psychiatric disorders with cutting-edge epigenetic tools

Clonal hematopoiesis drives femoral atherosclerosis in middle-aged adults

Amyloid immunotherapy for early Alzheimer's: Promising but fraught with challenges

Omega-3 fatty acids show potential in protecting brain health in older adults

Living near greenspace in midlife tied to slower cognitive decline in older age

New study reveals the genetic cause of Parkinson's disease

Novel Co-STAR cells show promise in targeting and eradicating cancer

Experts identify sex and gender differences in cognitive resistance and resilience to Alzheimer's disease

INTEGRA Biosciences’ pipettes help to cultivate success in agriculture

Small molecule discovery offers hope for treatment of Angelman syndrome

More than 1,000 small changes in DNA identified that influence age of first period

Fibrinogen-like protein 1 plays dual role in liver regeneration and hepatocellular carcinoma recurrence

From Africa to Eurasia: Genetic insights into human migration and cold adaptation

Pharmacogenomics: A pathway to personalized treatment in prostate cancer

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

Latest News