Cachexia News and Research

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Cachexia is a condition which denotes the excessive loss of weight. It occurs because of the depletion of adipose tissue and muscle mass in people who are not trying to lose weight.

Study identifies two genes associated with extreme nausea and vomiting during pregnancy

Most women experience some morning sickness during pregnancy, but about 2 percent of pregnant women experience a more severe form of nausea and vomiting.

21 Mar 2018

Heart failure patients who have anorexia have worse prognosis

Researchers of the German Centre for Cardiovascular Research (DZHK) have discovered that patients with heart failure who have anorexia are also more affected in their physical functional capacity and have worse prognosis.

12 Jan 2018

Study elucidates how aerobic exercise protects the sick heart

Regular exercise is considered an important form of treatment for heart failure, a condition in which the heart is unable to pump enough blood to meet the body's needs.

18 Aug 2017

Natural compounds in thyme and oregano may offer treatment for cachexia

Fresh thyme and oregano offer a savory touch to a tasty dish, but a University of Iowa researcher recently discovered natural compounds in the herbs that may offer a treatment for cachexia or "wasting syndrome" as it is more commonly known.

1 Aug 2017

Researchers understand how to prevent severe weight loss in cancer patients

Many cancer patients are susceptible to potentially lethal weight loss. Now researchers understand better why this happens, and perhaps how to prevent the condition.

25 Jul 2017

SLU scientists discover nuclear receptor that appears to play key role in muscle regeneration

Saint Louis University researchers report in Molecular Metabolism new findings that the nuclear receptor REV-ERB appears to play a key role in muscle regeneration, suggesting the receptor may be a good target for new drugs to treat a variety of muscle disorders and injuries.

14 Jun 2017

New approach could potentially prevent muscle wasting in muscular dystrophy and cancer

Monash University's Biomedicine Discovery Institute researchers have collaboratively developed a therapeutic approach that dramatically promotes the growth of muscle mass, which could potentially prevent muscle wasting in diseases including muscular dystrophy and cancer.

14 Jun 2017

Exosome isolation using ultracentrifugation

In the outpatient clinic and lab, our research studies aim to understand biological functions of exosomes and membrane particles.

From Beckman Coulter Life Sciences - Centrifugation 9 Feb 2017

Study links higher BMI to lower chances of getting hospice care

The heavier someone is, the less likely they are to have what many people might call a "good death", with hospice care and a chance to die at home, a new study finds. And that difference comes with a financial, as well as a personal, cost, the research shows.

8 Feb 2017

Researchers explore cause for increasing use of cannabis among older Americans

The U.S. Substance Abuse and Mental Health Services Administration has reported that cannabis use by persons over age 50 has outpaced recent growth observed across all other age groups.

11 Jan 2017

Scientists discover new mechanism responsible for regulation of glucose metabolism

Diabetes mellitus is a chronic disease that has become increasingly prevalent in the population: More than six million people are affected by the disease alone in Germany.

9 Nov 2016

Weight loss condition provides clues to why cancer immunotherapy may fail in many patients

A weight loss condition that affects patients with cancer has provided clues as to why cancer immunotherapy - a new approach to treating cancer by boosting a patient's immune system -- may fail in a substantial number of patients.

8 Nov 2016

New research explains how tumors may impair ability of the liver to respond to caloric deprivation

One of the worst cruelties of lethal cancer is the phenomenon called wasting, or in medical terms, cachexia (pronounced ka-CHEX-ia), in which a patient seems literally to diminish in bodily terms as the cancer ravages one or more internal organs.

8 Nov 2016

Biologic drugs may help prevent progressive bone loss in patients with RA

A new review by the International Osteoporosis Foundation Chronic Inflammation and Bone Structure Working Group concludes that early and aggressive treatment of Rheumatoid Arthritis (RA) with biologic drugs, specifically biological disease-modifying anti-rheumatic drugs (DMARDs), may be most effective in halting progressive bone loss in patients with RA.

7 Nov 2016

New, practical tool may help doctors to easily diagnose cachexia in cancer patients

About one third of cancer patients die because of cachexia - an involuntary weight loss, characterized primarily by muscle wasting and metabolic changes, which cannot be addressed or treated solely with increased food intake.

7 Nov 2016

Leading experts in iron deficiency to participate in 3rd European Iron Academy meeting

The 3rd European Iron Academy (EIA) will take place on the 12th and 13th September 2016 in Berlin, Germany, and will bring together over 450 clinicians with an interest in iron deficiency.

From CSL Ltd 16 Sep 2016

Selective manipulation of enzyme can stop cancer cachexia

Healthy fat tissue is essential for extended survival in the event of tumor-induced wasting syndrome (cachexia). In Nature Medicine, researchers at Helmholtz Zentrum München show that selective manipulation of an enzyme can stop unwanted metabolic processes.

30 Aug 2016

Researchers discover new role of cellular signaling molecule involved in release of hunger hormone

Researchers at UT Southwestern Medical Center have identified a previously unknown role of a cellular signaling molecule involved in release of the "hunger hormone" ghrelin, a finding that could have implications for optimal treatment of children taking beta blockers.

23 Aug 2016

New gene therapeutic approach could save people suffering from muscle wasting disease

A discovery by Washington State University scientist Dan Rodgers and collaborator Paul Gregorevic could save millions of people suffering from muscle wasting disease.

27 Jul 2016

Why does appetite loss occur during illness? An interview with Prof. Conti and Prof. Francesconi

Appetite, as a word, come from the Latin appetitus, meaning "desire for.” Therefore, appetite can be defined as a pleasurable sensation or the desire to eat. This sensation is coordinated by several brain areas associated with reward processing such amygdala, hippocampus, ventral pallidum, nucleus accumbens and striatum, and others.

28 Jun 2016