Hepatology News and Research

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Hepatology is the branch of medicine that incorporates study of liver, gallbladder, biliary tree and pancreas as well as management of their disorders.

One in four U.S. hepatologists screen positive for unhealthy alcohol use

One in four hepatologists in the United States screened positive for unhealthy alcohol use in a survey study conducted by UCLA.

16 Oct 2025

Study reports the world's first genetically engineered pig-to-human liver xenotransplantation

An important new study in the Journal of Hepatology, published by Elsevier, reports the world's first auxiliary liver xenotransplant from a genetically engineered pig to a living human recipient.

9 Oct 2025

Khat use linked to autoimmune hepatitis in young men

Khat (Catha edulis), a plant chewed for its stimulant effects by millions in East Africa and the Arabian Peninsula, is increasingly recognized for its hepatotoxic potential.

30 Sep 2025

Categorizing the risk factors for portal vein thrombosis in liver cirrhosis

Portal vein thrombosis (PVT) is a critical complication in liver cirrhosis (LC), significantly worsening portal hypertension and accelerating the progression to decompensation.

30 Sep 2025

Study identifies key molecular and clinical biomarkers for MASLD

The causal biomarkers for metabolic dysfunction-associated steatotic liver disease (MASLD) and their clinical value remain unclear.

25 Sep 2025

Targeting TGF-β signaling as a strategy to treat liver fibrosis

Liver fibrosis, a pathological scarring process resulting from chronic liver injury, represents a significant global health burden due to its potential progression to cirrhosis and hepatocellular carcinoma.

25 Sep 2025

Personalized risk information does not increase colorectal cancer screening rates

A new Indiana University School of Medicine clinical trial - the largest of its kind to date - found that providing personalized colorectal cancer risk information to patients and their health care providers did not improve screening rates for the deadly ailment.

16 Sep 2025

Postpartum mothers more likely to be cured of hepatitis C with bedside treatment

Hepatitis C, a bloodborne virus that damages the liver, can cause cirrhosis, liver cancer, liver failure and death if left untreated.

11 Sep 2025

New genetic test redefines diagnosis and management of hereditary pancreatitis

A new genetic test developed at Mayo Clinic is redefining how clinicians diagnose and manage hereditary pancreatitis.

11 Sep 2025

Two research papers shed light on how gut-brain interactions shape eating behaviors

Two new papers from Clinical Gastroenterology and Hepatology and Gastroenterology shed light on how gut-brain interactions, influenced by both biology and life circumstances, shape eating behaviors.

5 Sep 2025

How social challenges shape gut health and drive obesity risk

As obesity in America continues to rise at alarming rates, researchers are finding that diet and exercise are not the only driving factors.

4 Sep 2025

Single-cell transcriptomics reveals new players in liver regeneration

The liver is remarkable for its ability to regenerate after injury, yet when this process fails, acute liver failure (ALF) carries devastating outcomes.

2 Sep 2025

Clonogenic hepatocytes identified as engines of liver development

In a new study published in the Journal of Hepatology, researchers from the San Raffaele Telethon Institute for Gene Therapy (SR-Tiget) show that only 15–20% of hepatocytes in newborn mice - dubbed clonogenic hepatocytes - are responsible for generating over 90% of the adult liver mass.

29 Aug 2025

New global consensus offers hope for women with inflammatory bowel disease during pregnancy

For women with inflammatory bowel disease (IBD), pregnancy can be an uncertain time due to limited clinical data about how IBD medications impact pregnancy outcomes and infants who have been exposed to IBD medications in utero.

28 Aug 2025

Healthy diet and physical activity reduce risk of alcohol-related liver-specific mortality

A novel study investigating how physical activity and diet quality interact with different levels and patterns of alcohol consumption shows that healthy eating and increased levels of physical activity significantly lower the risk of alcohol-attributable liver-related mortality.

27 Aug 2025

Family history of liver disease significantly raises risk of severe alcohol-related hepatitis

In a groundbreaking study, research scientists from the Indiana University School of Medicine and Regenstrief Institute found that individuals with a parent who died from liver disease face more than double the risk of developing alcohol-associated hepatitis, one of the deadliest forms of alcohol-related liver disease, compared with similar heavy drinkers without that family history.

26 Aug 2025

Carriers of colibactin-producing E. coli face threefold increase in colorectal cancer risk

Researchers from Kyoto Prefectural University of Medicine and collaborating Japanese institutions found that patients carrying colibactin-producing Escherichia coli (pks+ E. coli) in their colon polyps were more than three times as likely to have a history of colorectal cancer compared to those without the bacterium.

22 Aug 2025

Hepatology News and Research

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