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New hybrid lens design drastically cuts 3D microscopy costs and complexity

A team led by Raju Tomer, professor of biological sciences at Columbia University, has created a new design for microscopes and microscope lenses that could push 3D tissue imaging beyond state-of-the-art systems while drastically cutting costs and complexity.

10 Jun 2026

Realistic cellular conditions revive previously dismissed drug candidates

A drug once dismissed as ineffective suddenly worked - when scientists tested it under more realistic conditions that mimic the human body.

9 Jun 2026

Study reveals how germinal centers consistently produce antibodies

A new study tracking thousands of B cells across more than 100 germinal centers in mice reveals how the system consistently produces highly effective antibodies.

7 Jun 2026

How dysregulated collagen IV homeostasis causes cerebral microbleeds

Millions of older adults have tiny brain hemorrhages called cerebral microbleeds, which are strongly associated with dementia, cognitive decline, and stroke.

2 Jun 2026

Tissue rigidity actively regulates cell polarity and embryonic development

Embryonic development is one of the most dynamic biological processes in nature. Cells and tissues organise and reorganise themselves following incredibly precise patterns, while remaining flexible and robust.

2 Jun 2026

Understanding mitochondrial biology in alcohol-associated liver disease and cancer

For decades, giant mitochondria-known as megamitochondria-have been recognized in liver biopsies from patients with alcohol-associated liver disease (ALD).

1 Jun 2026

Experimental vaccine triggers broadly neutralizing HIV antibodies in macaques

For years, researchers have been hoping for vaccines that protect people against not just one strain of HIV, but every strain of the quickly mutating virus.

28 May 2026

Scientists uncover how two proteins essential for immune cell development work together

Researchers at VIB, Ghent University, and VUB have uncovered how two proteins essential for immune cell development work together at the molecular level.

27 May 2026

Surface acids found crucial for bacterial shape and growth

Researchers have discovered how acids on the surface of bacteria give these microscopic organisms their characteristic "rod" shape-by keeping an enzyme at bay that would otherwise turn the cylindrical cells into shape-shifting blobs.

26 May 2026

Ohio State study unlocks the long-standing mystery of RNA interference

While scientists have known for over two decades that all cells use a strategy called RNA interference to regulate gene expression, a new study is the first to describe how a specific protein manages the step-by-step process of assembling the molecular complex that performs the regulatory job.

26 May 2026

Study explains how environmental acidity destabilizes internal cellular traffic

A new scientific study led by the Universidad Carlos III de Madrid (UC3M) describes the mechano-chemical mechanism by which the acidity of the cellular environment destabilizes microtubules, the "avenues" that organize internal cellular traffic.

26 May 2026

Silica nanoparticles dampen early allergy signals in mouse mast cells

This in vitro study found that negatively charged SiO2 nanoparticles suppressed antigen-induced degranulation and activation-marker changes in IgE-sensitized mouse bone marrow-derived mast cells. By contrast, mTiO2 nanoparticles showed cytotoxic and pro-inflammatory effects, including enhanced DNP-induced IL-6 release, suggesting nanoparticle composition can shape early allergic immune responses.

24 May 2026

Scientists visualize a key cell protein regulating inflammatory disease pathways

University of Cincinnati structural biologists are the first in the world to visualize a key cell protein as part of newly published research from the College of Medicine.

22 May 2026

Scientists capture immune cells attacking live melanoma cells in real time

Scientists at the Garvan Institute of Medical Research have captured, for the first time, 'housekeeping' immune cells actively attacking and engulfing live melanoma cells – a discovery that could change the way we approach treatment for one of Australia's most common and deadly cancers.

21 May 2026

Scientists link schizophrenia risk gene to early cortical neuron changes

Researchers at King's College London have identified the biological nature and timing of changes in human cortical neurons caused by altering activity of a schizophrenia-associated gene in developing human neurons.

20 May 2026

New AI framework maps systemic obesity damage at cellular resolution

Researchers at Helmholtz Munich, the Ludwig Maximilians University Munich (LMU) and collaborating institutions have developed an artificial intelligence (AI) framework that maps disease-related changes throughout the entire mouse body at cellular resolution.

20 May 2026