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'Me-too' drugs drive increased spending through higher prescribing

A long-running debate over prescription drug costs has centered on whether drug manufacturers are better rewarded for truly innovative medicines or so-called "me-too" drugs that may offer only incremental improvements over existing treatments but still command high prices.

3 Aug 2026

Newly-discovered protein acts as off switch for human immune cells

Mayo Clinic researchers have identified a protein that cancer cells use to shut down the body's immune response, a discovery that could help scientists develop new treatments that make cancer immunotherapies more effective.

3 Aug 2026

Secondhand smoke alters tooth enamel development in early life

Exposure to secondhand cigarette smoke during the first days of life can cause changes in tooth enamel mineralization without causing visible changes to the teeth.

31 Jul 2026

Immune cell navigation breakthrough offers hope for better anti-inflammatory drugs

A scientific collaboration between the University of Bath (UK) and the UMass Chan Medical School (USA) have determined how a specific type of white blood cells, called neutrophils, move through the body.

31 Jul 2026

Texas A&M researchers build AI tools for tuberculosis drug discovery

When researchers screen potential tuberculosis drugs, they often end up with too many options. Some look promising but later prove to be costly dead ends.

30 Jul 2026

New chemical method breaks rules to speed up drug discovery

Binghamton University chemists have discovered a new mechanism that could potentially lead to quicker outcomes in pharmaceutical research.

30 Jul 2026

Scientists uncover how muscle actin filaments grow and renew themselves

Biophysicists unraveled a mystery of how muscles form at the molecular level and how they maintain their function.

29 Jul 2026

Rice University chemists develop cheaper way to synthesize drugs

Pharmaceutical drugs often rely on chemical compounds found in the body. Take phosphate, a common compound cells use as a chemical switch.

29 Jul 2026

Scientists develop a promising way to create new antifungal drug candidates

Scientists at Imperial College London and The University of Manchester have developed a promising new way to create safer and more effective treatments for life-threatening fungal infections.

29 Jul 2026

Researchers find potential pathway to improve glioblastoma treatment

New research published in Neuro-Oncology gives a glimpse at promising discoveries that could help shape the future of glioblastoma treatment and patient outcomes.

29 Jul 2026

New antimicrobials could help tackle deadly drug-resistant infections

Scientists at Imperial College London and The University of Manchester have developed a promising new way to create safer and more effective treatments for life-threatening fungal infections.

29 Jul 2026

A closer look at Parkinson’s brains finds tau where standard tests saw little

Researchers used single-molecule and super-resolution imaging to profile protein aggregates across six brain regions from 29 post-mortem donors, detecting high-intensity phosphorylated tau aggregates in the Parkinson’s disease putamen despite negligible conventional tau staining. PD cases with dementia showed greater tau burden than those without dementia, while the assay did not detect a PD-specific population of nanoscopic alpha-synuclein aggregates.

29 Jul 2026

Blocking the Axl receptor may offer a new way to promote bone formation

Osteoporosis is one of the most common age-related bone diseases, affecting millions of people worldwide and increasing the risk of fractures, disability, and reduced quality of life.

28 Jul 2026

TGen joins Collaborative Research Network for Parkinson's disease research

The Translational Genomics Research Institute (TGen), part of City of Hope, today announced it has been selected as part of a national team to join the Collaborative Research Network (CRN), an international, multi-institutional initiative focused on addressing high-priority research questions in Parkinson's disease.

28 Jul 2026

Exeter scientists uncover how doxycycline disarms bacteria

Scientists have discovered two new mechanisms for how a well-established antibiotic works, paving the way for potential development of new antibiotic treatment.

28 Jul 2026

Study reveals how pushing and pulling forces drive blood vessel formation

How do blood vessels form to reliably supply the body with oxygen and nutrients? A research team at the University of Basel has uncovered a key mechanism by which cells join to build new blood vessels.

28 Jul 2026

Scientists uncover hidden brain energy dynamics during REM sleep

Our brain demands a lot of energy compared to our other organs. However, it can also make do when energy supplies are sparse, flexibly performing information processing using what is available.

27 Jul 2026

St. Jude scientists uncover regulatory mechanism for crucial developmental pathway

St. Jude Children's Research Hospital scientists uncovered a regulatory mechanism for signaling of Sonic Hedgehog (SHH), a pathway essential for embryonic development.

27 Jul 2026

Dengue virus infects memory B cells to evade immune defenses

Researchers at the University of Vermont Robert Larner, M.D. College of Medicine and Upstate Medical University in Syracuse, NY, have discovered that dengue virus can infect and replicate inside memory B cells, immune cells traditionally understood to help protect the body from infection.

27 Jul 2026

Primate study reveals molecular basis of red-green color vision

Human color vision depends on three types of cone cells in the retina. Although all three contain the same light-absorbing molecule, 11-cis-retinal, differences in the surrounding protein determine sensitivity to red, green, or blue light.

27 Jul 2026