Neurodegenerative Disease News and Research

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Restoring brain energy balance reverses advanced Alzheimer’s disease in mouse models

For over a century, Alzheimer's disease (AD) has been considered irreversible. Consequently, research has focused on disease prevention or slowing, rather than recovery.

6 Jan 2026

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

In our latest interview, News-Medical speaks with Rosanna Zhang from ACROBiosystems about utilizing organoids for disease modeling in the field of neuroscience research.

From ACROBiosystems 6 Jan 2026

Targeting CSE enzyme may offer new pathways for Alzheimer’s treatment

Scientists at Johns Hopkins Medicine say results of a new National Institutes of Health-funded study are advancing efforts to exploit a new target for Alzheimer's disease: a protein that manufactures an important gas in the brain.

30 Dec 2025

Restoring brain energy balance reverses Alzheimer’s disease in mouse models

For over a century, Alzheimer's disease (AD) has been considered irreversible. Consequently, research has focused on disease prevention or slowing, rather than recovery.

23 Dec 2025

Distant astrocytes found to play a key role in spinal cord repair

Cedars-Sinai investigators have discovered a healing mechanism that could one day be harnessed to help treat patients with spinal cord injuries, stroke, and neurological conditions such as multiple sclerosis.

17 Dec 2025

Traumatic brain injury disrupts brain drainage and accelerates Alzheimer’s risk

University of Virginia School of Medicine researchers have uncovered how and why traumatic brain injury (TBI) increases the risk for Alzheimer's disease, and their work suggests a potential way to prevent that increased risk.

16 Dec 2025

Optogenetic tool helps decipher mechanisms of brain dysfunction in Huntington’s disease

Synaptic plasticity — the brain's ability to modify the connections between neurons to support learning — is one of the neural functions profoundly altered in Huntington's disease, with a direct impact on brain function.

10 Dec 2025

Online reference library provides a more accurate picture of drug exposure

Doctors and researchers try to understand what medications a person has taken by asking patients directly or by looking at medical records. But this information is often incomplete.

9 Dec 2025

Smartphone motor tests can predict dopamine deficiency in Parkinson’s disease without brain scans

Researchers explore the use of smartphones coupled with clinical scores to evaluate motor function and predict dopamine deficiency.

7 Dec 2025

Study provides first molecular evidence that ferroptosis can drive neurodegeneration

Researchers at Helmholtz Munich, the Technical University of Munich and the LMU University Hospital Munich uncovered a mechanism that protects nerve cells from premature cell death, known as ferroptosis.

4 Dec 2025

New imaging method reveals nanodomains inside ALS-linked protein droplets

Inside the cell reside many tiny assembly factories and warehouses that gather together all of the proteins and RNAs-which carry out instructions from our DNA-that a living being needs.

26 Nov 2025

Obesity-related metabolic stress may affect brain health far earlier than expected

For decades, scientists have known that what harms the body often harms the brain. Conditions such as obesity, high blood pressure and insulin resistance strain the body's vascular and metabolic systems.

25 Nov 2025

Diesel exhaust particles can impair microglial functions

Diesel exhaust particles can disturb the function of human brain immune cells, known as microglia, according to a recent study led by the University of Eastern Finland.

25 Nov 2025

Scientists uncover how brain enzyme OTULIN controls tau expression

Scientists have uncovered a surprising mechanism by which a brain enzyme called OTULIN controls the expression of tau, the protein that forms toxic tangles in Alzheimer's disease.

25 Nov 2025

Researchers launch phase 2 trial to test swallowing therapy for people with early Parkinson's

Swallowing difficulties, or dysphagia, affect up to 80% of people with Parkinson's disease and can lead to serious complications, including malnutrition, aspiration and reduced quality of life.

24 Nov 2025

Astrocyte-driven approach shows potential to reverse cognitive decline in Alzheimer’s

Researchers at Baylor College of Medicine have discovered a natural mechanism that clears existing amyloid plaques in the brains of mouse models of Alzheimer's disease and preserves cognitive function.

21 Nov 2025

Coffee protects the brain, metabolism, and immunity at the molecular level

This review uncovers the molecular networks of coffee's compounds, showcasing their antioxidant and neuroprotective effects on immunity and metabolism.

19 Nov 2025

Muscle-driven gene therapy shows promise for protecting memory in Alzheimer’s

Alzheimer's disease (AD) is a devastating cause of memory loss and cognitive decline, for which no curative treatment is available.

18 Nov 2025

TRIMTECH Therapeutics appoints Dr Mike Hutton to Scientific Advisory Board

TRIMTECH Therapeutics, a biotech company creating novel, small molecule therapeutics that selectively degrade protein aggregates, to combat neurodegenerative diseases, today announced the appointment of Dr Mike Hutton to its Scientific Advisory Board (SAB).

From TRIMTECH Therapeutics 12 Nov 2025

Amyloid-clearing drug fails to change waste clearance function in the brains of Alzheimer's patients

A group from Osaka Metropolitan University in Japan, led by graduate student Tatsushi Oura and Dr. Hiroyuki Tatekawa, found that treatment using the drug lecanemab to remove amyloid plaques in the brain does not change the waste clearance function in the brains of Alzheimer's disease (AD) patients in the short term.

11 Nov 2025

Neurodegenerative Disease News and Research

Restoring brain energy balance reverses advanced Alzheimer’s disease in mouse models

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

Targeting CSE enzyme may offer new pathways for Alzheimer’s treatment

Restoring brain energy balance reverses Alzheimer’s disease in mouse models

Distant astrocytes found to play a key role in spinal cord repair

Traumatic brain injury disrupts brain drainage and accelerates Alzheimer’s risk

Optogenetic tool helps decipher mechanisms of brain dysfunction in Huntington’s disease

Online reference library provides a more accurate picture of drug exposure

Smartphone motor tests can predict dopamine deficiency in Parkinson’s disease without brain scans

Study provides first molecular evidence that ferroptosis can drive neurodegeneration

New imaging method reveals nanodomains inside ALS-linked protein droplets

Obesity-related metabolic stress may affect brain health far earlier than expected

Diesel exhaust particles can impair microglial functions

Scientists uncover how brain enzyme OTULIN controls tau expression

Researchers launch phase 2 trial to test swallowing therapy for people with early Parkinson's

Astrocyte-driven approach shows potential to reverse cognitive decline in Alzheimer’s

Coffee protects the brain, metabolism, and immunity at the molecular level

Muscle-driven gene therapy shows promise for protecting memory in Alzheimer’s

TRIMTECH Therapeutics appoints Dr Mike Hutton to Scientific Advisory Board

Amyloid-clearing drug fails to change waste clearance function in the brains of Alzheimer's patients

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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