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Evolutionary noncoding RNAs reveal new targets for cancer therapy

In cancer research, one person's junk is increasingly becoming another person's treasure. Scientists have now uncovered new evidence showing how recently evolved "junk DNA" genetic elements can become integrated into ancient cellular pathways that regulate cancer.

1 Jul 2026

Botanical prebiotics may steer skin microbes toward healthier balance

Researchers tested plant-derived prebiotic candidates against selected skin-associated bacteria and found that garlic, flaxseed, and mango ginger extracts inhibited S. aureus or acne-associated C. acnes in vitro. Onion and guduchi extracts modestly promoted S. epidermidis, suggesting a microbiome-targeted skincare route that now needs validation in skin models and human studies.

30 Jun 2026

Genetic research links KDF1 mutation to impaired dental epithelial organization

Dental enamel is the hardest substance in the human body, protecting teeth from wear, temperature changes, and decay. However, enamel cannot regenerate once damaged. Inherited disorders, such as amelogenesis imperfecta, disrupt enamel formation during development, leaving affected individuals with fragile, discolored, and decay-prone teeth.

30 Jun 2026

New accessible multiplex imaging workflow advances spatial liver research

Spatial biology technologies are reshaping modern biomedical research by enabling the visualization of cellular organization and interactions within intact tissues.

26 Jun 2026

AI and multiomics reveal how gut bacteria trigger colon cancer

Over the past two decades, high‑throughput sequencing has dramatically expanded our understanding of the gut microbiome's composition.

26 Jun 2026

Natural compound puerarin may protect against cholestatic liver fibrosis

A recent study published in Current Molecular Pharmacology demonstrates that puerarin-a bioactive isoflavone derived from Kudzu root and widely used in traditional Chinese medicine-may offer significant therapeutic benefits against cholestatic liver fibrosis, a progressive pathological condition arising from impaired bile formation and flow that currently lacks effective pharmacotherapies.

25 Jun 2026

Lactate and lactylation play multifaceted roles in pancreatic ductal adenocarcinoma

A comprehensive review recently published in Current Molecular Pharmacology illuminates the pivotal, multifaceted roles of lactate and its downstream protein modification, lactylation, in pancreatic ductal adenocarcinoma (PDAC).

25 Jun 2026

Study uncovers mechanism driving metastasis in aggressive gastric cancer

A study recently published in Current Molecular Pharmacology has uncovered a novel mechanism by which the long non‑coding RNA PVT1 and the translation initiation factor EIF4A1 cooperate to drive gastric cancer metastasis.

25 Jun 2026

Natural bioactive compounds target miR-29a molecule to prevent cancer development

A study published in Current Molecular Pharmacology provides a comprehensive analysis of microRNA-29a (miR-29a) as a pivotal regulator in cancer development, and examines how natural bioactive compounds may offer a promising strategy for cancer prevention by modulating its expression.

25 Jun 2026

Researchers uncover key mechanism driving chronic Sjögren disease

Sjögren disease, an autoimmune disease characterized by dry mouth and dry eyes, may reduce patients’ quality of life.

24 Jun 2026

Melatonin improves skin flap survival by reducing ferroptosis

Random-pattern skin flaps are widely used to repair defects caused by trauma, burns, tumor removal, and other injuries because they can be designed without depending on a single named blood vessel.

23 Jun 2026

Researchers identify molecular pathway that delays diabetic wound healing

Diabetic foot ulcer (DFU) is one of the most serious complications of diabetes and a major cause of lower-limb amputation.

23 Jun 2026

Scientists uncover new molecular mechanism driving gastrointestinal stromal tumors

Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the digestive tract, with KIT mutations driving approximately 75% to 80% of cases.

23 Jun 2026

Researchers advocate local data strategies for early cancer detection

Researchers are calling for the application of locally driven strategies, supported by stronger regional evidence, to improve early cancer detection and precise care.

22 Jun 2026

Aging immune cells may explain why autoimmunity rises later in life

A new Review reveals how aging can push the immune system into a paradoxical state, weaker against threats yet more prone to attacking the body’s own tissues.

21 Jun 2026

Brazilian researchers identify cell molecule that drives cancer progression

Researchers at the Federal University of São Paulo (UNIFESP) in Brazil have identified a molecule on the surface of cells that could be a promising therapeutic target against cancer.

18 Jun 2026

Sidewalk yeast species could lead to eco-friendly mosquito traps

An orange-colored yeast species isolated from a Baltimore sidewalk several years ago could be the basis of eco-friendly mosquito traps that reduce malaria transmission, according to a new study from researchers at the Johns Hopkins Bloomberg School of Public Health.

17 Jun 2026

New pico-calorimeter detects antibiotic resistance via direct heat traces

When living cells grow, divide, or respond to drugs, they give off tiny amounts of heat that offer information about what the cells are doing. But since these heat signals are so vanishingly small, they have been traditionally impossible to measure directly.

17 Jun 2026

Novel analysis identifies unique proliferation gene alterations in diverse cancer patients

New research to be presented today (Monday) at the annual conference of the European Society of Human Genetics shows that a cancer patient's genetic ancestry can have a significant effect both on how their disease progresses and their survival. In the largest study of its kind, researchers examined nearly 1,900 specific genetic changes in tumors in order to measure whether certain mutations were more common in patients with different historic geographic origins.

15 Jun 2026

Study identifies key protein driving colon cancer drug resistance

One of the most widely used chemotherapeutic agents for colorectal cancer is 5-fluorouracil (5-FU), a cornerstone treatment that has improved outcomes for countless patients.

9 Jun 2026