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SIRT6 identified as a critical safeguard of spinal disc health

Low back pain is the most prevalent musculoskeletal condition worldwide and is closely tied to the progressive degeneration of intervertebral discs.

5 Jun 2025

Pitt researchers challenge a decades-old assumption about brain plasticity

A new study from Pitt researchers challenges a decades-old assumption in neuroscience by showing that the brain uses distinct transmission sites - not a shared site - to achieve different types of plasticity.

3 Jun 2025

Researchers discover key mechanism behind synapse maturation

Researchers from the lab led by Prof. Joris De Wit (VIB-KU Leuven) have discovered an important clue to how connections between brain cells, known as synapses, mature.

21 May 2025

Combination of two drugs shows promise in treating B-cell acute lymphoblastic leukemia

A combination of two drugs could improve outcomes and reduce the need for toxic chemotherapy for B-cell acute lymphoblastic leukemia (B-ALL), the commonest cancer in childhood and one that can be particularly difficult to treat in older patients, according to Cambridge scientists.

20 May 2025

Pain clinic CEO faced 20 years for making patients ‘human pin cushions.’ He got 18 months.

Federal prosecutors sought a maximum prison sentence of nearly 20 years for the CEO of Pain MD, a company found to have given hundreds of thousands of questionable injections to patients, many reliant on opioids.

15 May 2025

Lipid accumulation levels reveal hidden osteoporosis risk

Researchers investigate the use of lipid accumulation products as a predictor of osteoporosis.

14 May 2025

Advanced microscopy reveals how hormonal fluctuations shape the brain

Hormone levels fluctuate like the tides, ebbing and flowing according to carefully orchestrated cycles.

13 May 2025

Lipid buildup predicts weaker bones once it passes a critical threshold

A large cross-sectional study using NHANES data found a non-linear negative relationship between lipid accumulation product (LAP) and lumbar spine bone mineral density (BMD). The association became significant only above a threshold value (ln-LAP > 2.846), independent of BMI.

12 May 2025

An Arm and a Leg: A health policy veteran puts 2025 in perspective

News has been coming out of Washington, D.C., since the start of the second Donald Trump administration like water out of a fire hose. It can feel impossible to stay on top of all the changes.

12 May 2025

Body mass index linked to knee structural changes in 33-year-olds

Mild structural changes visible in knee MRI scans are already common among adults in their thirties - even in those without knee pain or other symptoms.

5 May 2025

Study links impaired synaptic pruning to autism

Autism spectrum disorder (ASD) is a complex neurodevelopmental condition in which affected individuals experience difficulties in social communication and exhibit restricted, repetitive patterns of behavior or interests.

30 Apr 2025

Noninvasive decoder could help restore movement after spinal cord injury

When a person sustains an injury to the spinal cord, the normal communication between the brain and the spinal circuits below the injury are interrupted, resulting in paralysis.

29 Apr 2025

Largest study identifies new genetic targets for osteoarthritis treatment

Researchers have uncovered multiple new genes and genetic pathways that could lead to repurposing hundreds of existing drugs for osteoarthritis, the most common form of arthritis.

28 Apr 2025

Targeting zombie cells could revolutionize chronic back pain treatment

In a preclinical study led by McGill University researchers, two drugs targeting "zombie cells" have been shown to treat the underlying cause of chronic low back pain. The condition affects millions of people worldwide.

22 Apr 2025

GLP1 agonists linked to depression risk in new genetic study

A groundbreaking study published in the journal Current Neuropharmacology highlights a concerning potential link between Glucagon-like Peptide-1 (GLP1) receptor agonists-widely used in blockbuster drugs like Ozempic-and the risk of depression and suicidal ideation (SI).

17 Apr 2025

Weight-loss lifestyle changes slow bone loss in older adults

Researchers evaluate the effects of a weight-loss lifestyle intervention on age-related bone deterioration.

14 Apr 2025

$Diet and exercise habits in your 60s linked to lower fracture and heart death risk$

Diet and exercise habits in your 60s linked to lower fracture and heart death risk

A long-term study in older adults links higher-quality diets to lower risks of hip fracture and cardiovascular death. Researchers suggest that framing bone health through heart disease awareness may better engage men in preventive action.

7 Apr 2025

Scientists make breakthrough in understanding the causes of spina bifida

Scientists at Rady Children's Institute for Genomic Medicine, and the Department of Neurosciences and Pediatrics at the University of California, San Diego, have made a significant breakthrough in understanding the causes of spina bifida, a serious birth defect affecting thousands of newborns each year.

1 Apr 2025

Besifovir dipivoxil maleate offers comparable efficacy and improved safety for hepatitis B patients

Hepatitis B is a liver infection cause by the hepatitis B virus (HBV), and long-term hepatitis B infections that last longer than six months are considered "chronic".

24 Mar 2025

Research reveals how dendrites connect memories in the brain

If you've ever noticed how memories from the same day seem connected while events from weeks apart feel separate, a new study reveals the reason: Our brains physically link memories that occur close in time not in the cell bodies of neurons, but rather in their spiny extensions called dendrites.

22 Mar 2025