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Inflammatory signals from vesicles increase cancer cell aggressiveness and invasiveness

Pro-inflammatory M1 macrophages involved in immune responses accelerate the progression of melanoma through the extracellular vesicles they secrete, a recent study from the University of Eastern Finland shows. The findings were published in Cell Communication and Signaling.

3 Mar 2026

Chronic back pain linked to heightened sound sensitivity in the brain

People with chronic back pain process everyday sounds differently, and more intensely, than people without pain, according to new research from the University of Colorado Anschutz.

2 Mar 2026

Study reveals hydration energetics as key to nanoparticle performance in medicine

Researchers at Arizona State University have uncovered a key scientific principle that governs how what's coated on the surfaces of engineered nanoparticles may ultimately control how they work in our bodies.

2 Mar 2026

Blocking growth hormone receptor may improve treatment response in lung cancer

Researchers at Ohio University have discovered what may be a new way to fight lung cancer that is resistant to other treatments.

2 Mar 2026

Experts identify safest and most effective diets for IBS management

This review in Nutrients evaluates the scientific evidence, clinical effectiveness, and safety of major dietary strategies for irritable bowel syndrome, including traditional advice, low-FODMAP, gluten-free, Mediterranean, and starch- and sucrose-reduced diets. It concludes that while the low-FODMAP diet has the strongest short-term evidence, no single approach fits all patients, and dietitian-led personalization is essential.

2 Mar 2026

High-dose curcumin fails to produce lasting gut-microbiome changes in IBD patients

In an open-label study of 29 men, including patients with ulcerative colitis and Crohn’s disease in remission, 6 g per day of curcumin for eight weeks led to modest, transient shifts in gut microbiota composition without sustained restructuring. Despite achieving high fecal concentrations and minimal systemic bioavailability, curcumin did not produce durable microbiome changes, and disease activity scores remained stable.

2 Mar 2026

COVID-19 ARDS survivors face lasting disability and high late mortality, researchers report

In this single-center ambispective cohort of 283 Polish patients with COVID-19–related ARDS requiring invasive mechanical ventilation, cumulative mortality reached 44.5% at four years after ICU admission. Among survivors, substantial proportions reported persistent functional limitations, insomnia, fatigue, and reduced quality-adjusted life years.

2 Mar 2026

Seeing the unseen in bladder cancer surgery

Ten years ago, a discussion in Milan set a demanding project in motion. In a meeting between a biologist and a urologist, one question kept returning: why do so many bladder cancer patients face recurrence even after surgery that follows every guideline?

2 Mar 2026

Study reveals cellular and metabolic landscape of lymph node metastasis in breast cancer

A recent integrative analysis of single-cell sequencing and single-cell spatial mapping of lymph node metastasis in breast cancer reveals novel mechanisms of the metabolic-immune interaction that drive the spread of breast cancer.

2 Mar 2026

ATP delivery fixes dysfunctional dopamine packaging in Parkinson's neurons

A new study shows how dysfunctional packaging of the neurotransmitter dopamine triggers toxic processes in neurons - and how this can be repaired with simple delivery of energy (ATP).

2 Mar 2026

A new standard for preventing post-surgery kidney cancer relapse

Patients with a common form of kidney cancer called clear cell renal cell carcinoma (ccRCC) who have a high risk of recurrence after surgery showed significantly improved disease-free survival when treated with an oral combination regimen that includes belzutifan, a HIF-2α inhibitor, given with standard immune therapy pembrolizumab.

1 Mar 2026

Common cardio drugs proven safe in myeloma patients

Commonly prescribed cardiovascular medications—such as statins, diuretics, and blood pressure drugs—appear to have little or no negative impact on survival among people living with multiple myeloma, according to new international research.

1 Mar 2026

Engineered proteins track gene expression in living primate brains

Gene therapy has been successfully used to treat a number of diseases, including immune deficiencies, hereditary blindness, hemophilia and, recently, Huntington's disease, a fatal neurological disorder.

27 Feb 2026

Acoziborole receives positive opinion for single-dose sleeping sickness treatment

The European Medicines Agency's Committee for Medicinal Products for Human Use (CHMP) has granted a positive opinion to Acoziborole Winthrop (acoziborole) as a single-dose oral treatment for both early- and advanced-stage gambiense sleeping sickness in adults as well as in adolescents 12 years and older weighing at least 40 kilograms.

27 Feb 2026

Tick-derived protein discovery can advance treatment for inflammatory diseases

When the immune system detects a harmful or foreign agent it triggers an inflammatory response small proteins called chemokines direct immune cells to the site of the injury or infection, resulting in the invader being inactivated.

27 Feb 2026

He needs an expensive drug. A copay card helped — until it didn’t.

Over the course of 2025, Jayant Mishra of Mission Viejo, California, progressively developed scaly, itchy red patches on his skin. Then came the pain and swelling in the joints of his hands, making it difficult to do his work at a bank.

27 Feb 2026

Solving the mystery of a year-long pain crisis

Taffy Hopkins, 73, was in debilitating pain for a year, leaving her bedridden. The Palm Beach resident had been told she was simply experiencing migraines, but the migraine medications did not work and left her suffering, with no answers in sight. After seeking care at NYU Langone Medical Associates—West Palm Beach, 1515 North Flagler Drive, she finally received a diagnosis—and relief.

26 Feb 2026

New approach to reducing radiation toxicity

Radiation therapy is highly effective at killing cancer cells, but it often harms healthy skin around the treatment area, a common side effect experienced by up to 95% of cancer patients undergoing treatment. In worst-case scenarios, it can result in delayed or halted treatment.

26 Feb 2026

New biomarkers for targeted gastric therapy

HER2-positive gastric cancer accounts for a substantial proportion of advanced cases and has long been treated with HER2-targeted therapies. While trastuzumab deruxtecan has shown superior activity compared with earlier agents, most patients either fail to respond initially or eventually develop resistance.

26 Feb 2026

Misdiagnosed Parkinson's patient regains life after NPH treatment

At age 66, Richard "Dick" Nash first suspected something might be wrong when he participated in a Dallas walk for juvenile diabetes in honor of his granddaughter.

26 Feb 2026