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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Radboud university medical center reveals how BCG vaccine works against tuberculosis

Not only the acquired immune system but also the innate immune system has a memory. And the BCG vaccine against tuberculosis can stimulate this memory. After a BCG vaccination the innate immune system responds better to a wide range of other infections. Mihai Netea and colleagues from Radboud university medical center discovered and described how that works. They think that the old vaccine could be useful for specific target groups, such as the elderly.

23 Sep 2015

New gene mutation linked to fatal swelling in unborn and newborn babies

Scientists have discovered a new gene mutation that causes potentially fatal swelling in unborn and newborn babies. Identifying the gene is the first step toward a future diagnostic test and targeted treatment for this condition.

23 Sep 2015

People with specific genotype are more deeply affected by life experiences, reveals study

People with a certain type of gene are more deeply affected by their life experiences, a new study has revealed.

23 Sep 2015

Johns Hopkins scientists discover earliest premalignant genetic changes that mark potential onset of lung cancer

Working with tissue, blood and DNA from six people with precancerous and cancerous lung lesions, a team of Johns Hopkins scientists has identified what it believes are among the very earliest “premalignant” genetic changes that mark the potential onset of the most common and deadliest form of disease.

23 Sep 2015

Mayo Clinic's Gianrico Farrugia highlights five areas that may impact patient care

How is individualized medicine working? Let us count the ways. That's just what Mayo Clinic Vice President Gianrico Farrugia, M.D., did this morning in his opening keynote at the 4th annual Individualizing Medicine Conference. The core of his talk highlighted five areas in which the knowledge and know-how from the human genome will be most impactful in patient care, not just at Mayo Clinic, but anywhere in the nation and globally.

23 Sep 2015

Scientists uncover how embryonic stem cells inhibit virus expression

Scientists from the Institute of Molecular and Cell Biology, a research institute under the Agency for Science, Technology and Research, Singapore, have uncovered the mechanisms which embryonic stem cells employ to inhibit virus expression.

22 Sep 2015

Protein-based modular system could help detect viral infection or kill cancer cells

MIT biological engineers have developed a modular system of proteins that can detect a particular DNA sequence in a cell and then trigger a specific response, such as cell death.

22 Sep 2015

Boehringer Ingelheim, BioMed X apply crowdsourcing approach to establish research team for identifying COPD treatment

Boehringer Ingelheim and BioMed X announced today that they have successfully applied a crowdsourcing approach to establish a research team of outstanding scientists from around the world with bright ideas, who will endeavor to identify new approaches for the treatment of patients with chronic obstructive pulmonary disease (COPD).

21 Sep 2015

Using deep learning to analyze genetic mutations: an interview with Brendan Frey

To understand deep learning in the context of genetic disease, you need to understand shallow learning first. Shallow learning relates mutations to diseases by looking for mutations that commonly occur in patients with a disease. It’s a commonly used method.

21 Sep 2015

UF researchers find a way to kill insects that carry devastating citrus greening bacterium

Researchers with the University of Florida and several other institutions have found a way in laboratory tests to use 200 times less insecticide and yet still kill as many insects that carry the devastating citrus greening bacterium.

21 Sep 2015

Novel nebuliser could one day deliver life-saving cancer drugs

A revolutionary nebuliser developed by RMIT University researchers could one day deliver life-saving cancer drugs and vaccines traditionally given by injection.

21 Sep 2015

Glide Technologies, Cilian collaborate to develop solid dose formulation of recombinant influenza vaccine

Glide Technologies, the development company focused on solid dose formulations of therapeutics and vaccines, today announced that it has entered a collaboration with German biotechnology company Cilian AG to develop a solid dose formulation of Cilian's experimental recombinant influenza vaccine, CiFlu, for delivery using Glide's patient-friendly SDI delivery device.

21 Sep 2015

Satellite DNA plays vital regulatory role in how organisms adapt to environmental changes

A team of geneticists led by Prof. Đurđica Ugarković of the Croatian Ruđer Bošković Institute have for the first time proved that satellite DNA plays an important regulatory role in how organisms adapt to stressful changes in their environment. These results could in the future help scientists explain how an organism successfully survives stress.

21 Sep 2015

Urinary tract infections could be treated more efficiently using DNA sequencing device

Urinary tract infections (UTIs) could be treated more quickly and efficiently using a DNA sequencing device the size of a USB stick - according to research from the University of East Anglia.

From Oxford Nanopore Technologies 21 Sep 2015

Cattle virus found in human cancer cells

Evidence of exposure to bovine leukaemia virus (BLV) has been found in human breast cancer samples. This is the first suggestion of a possible link between infection with a leukaemia virus prevalent in cows and breast cancer in humans.

18 Sep 2015

Thomas Jefferson University provides routine genomic fingerprinting to cancer patients

Cancer medicine is moving towards understanding what drives each particular patient's cancer. But not every patient has had access to this level of individualized care.

18 Sep 2015

PharmaMar begins phase II 'Basket' trial to evaluate safety, efficacy of PM1183 in advanced solid tumors

PharmaMar announced today the start of a multicenter, international, open-label, exploratory phase II "Basket" trial (NCT02454972) to evaluate the efficacy and safety of the anticancer agent PM1183 (lurbinectedin) in advanced solid tumors.

18 Sep 2015

Researchers identify triple mechanism that prevents onset of chromosomal instability

Universitat Autònoma de Barcelona researchers have identified for the first time the triple mechanism that stops chromosome separation in response to situations that compromise the integrity of the genetic information. The loss of this response capacity is characteristic of cancerous cells.

18 Sep 2015

Research: Spindle matrix protein supports assembly of spindle matrix, microtubules in cell-division process

Every high school biology class learns about the tiny cells that comprise our bodies, as well as about many of the diverse actions that they perform.

18 Sep 2015

New optimising ChIP sequencing library preparation guide

Chromatrap®, a business unit of Porvair Sciences, has produced an informative new guide entitled ‘Top 10 Tips for ChIP-seq Library Preparation'.

From Chromatrap® - Porvair Sciences Ltd 18 Sep 2015

DNA News and Research

Further Reading

Radboud university medical center reveals how BCG vaccine works against tuberculosis

New gene mutation linked to fatal swelling in unborn and newborn babies

People with specific genotype are more deeply affected by life experiences, reveals study

Johns Hopkins scientists discover earliest premalignant genetic changes that mark potential onset of lung cancer

Mayo Clinic's Gianrico Farrugia highlights five areas that may impact patient care

Scientists uncover how embryonic stem cells inhibit virus expression

Protein-based modular system could help detect viral infection or kill cancer cells

Boehringer Ingelheim, BioMed X apply crowdsourcing approach to establish research team for identifying COPD treatment

Using deep learning to analyze genetic mutations: an interview with Brendan Frey

UF researchers find a way to kill insects that carry devastating citrus greening bacterium

Novel nebuliser could one day deliver life-saving cancer drugs

Glide Technologies, Cilian collaborate to develop solid dose formulation of recombinant influenza vaccine

Satellite DNA plays vital regulatory role in how organisms adapt to environmental changes

Urinary tract infections could be treated more efficiently using DNA sequencing device

Cattle virus found in human cancer cells

Thomas Jefferson University provides routine genomic fingerprinting to cancer patients

PharmaMar begins phase II 'Basket' trial to evaluate safety, efficacy of PM1183 in advanced solid tumors

Researchers identify triple mechanism that prevents onset of chromosomal instability

Research: Spindle matrix protein supports assembly of spindle matrix, microtubules in cell-division process

New optimising ChIP sequencing library preparation guide

Understanding the DNA Damage Response in Innate Immunity eBook

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