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Researchers use 'multiomics' approach to study newborn mouse heart

During the first days of life, the heart of a newborn mouse adapts to entirely new physiological conditions, larger volume loads and an increased energy demand. As a result, fundamental changes occur in the heart. Studies have shown that the heart of neonate mouse retains its ability to effectively repair tissue damage.

4 Jun 2018

Researchers reveal potent new mechanism of action for treatment of IBD

Professor Akiyoshi Fukamizu's research group of Life Science Center for Survival Dynamics, University of Tsukuba, Eisai Co., Ltd. and its gastrointestinal business subsidiary EA Pharma Co., Ltd. have revealed a mechanism in which an analogue (ER-464195-01) of Eisai's in-house discovered E6007 inhibits integrin activation by dissociating interaction between calreticulin (CRT) and integrin α 4 (ITGA4), suppressing adhesion and infiltration of leukocytes overall.

25 May 2018

Researchers discover new disease mechanism in chronic tobacco smokers

Research published in the journal Clinical Science suggests that an immune signaling protein called interleukin-26 is increased among chronic smokers with lung disease and this involvement reveals disease mechanisms of interest for developing more effective therapy for these hard-to-treat patients.

21 May 2018

Scientists identify new potential target to combat acute myeloid leukemia

AML is not a single disease. It is a group of leukemias that develop in the bone marrow from progenitors of specialized blood cells, the so-called myeloid cells. Rapidly growing and dividing, these aberrant cells crowd the bone marrow and bloodstream, which can be fatal within weeks or months if the disease is left untreated.

18 May 2018

Study provides insights into how immune cells kill bacteria with acid

The first line of immune defense against invading pathogens like bacteria are macrophages, immune cells that engulf every foreign object that crosses their way. After enclosing it in intracellular membrane vesicles, a process called phagocytosis, macrophages kill their prey with acid.

17 May 2018

DDN and Parabricks announce integrated technology solution that accelerates genome analysis

DDN Storage and Parabricks today announced the availability of a jointly-integrated technology solution that provides massive acceleration for analysis of human genomes.

16 May 2018

Researchers shed light on biological mechanism underlying link between height and cognition

Reports from several studies have identified a link between height and general cognitive ability, or intelligence, but the mechanisms underlying this association are not well known. Researchers from the University of Helsinki, University of California San Diego and Boston University found that this association is mediated by cortical surface area.

14 May 2018

LogicBio team to present data on preclinical effectiveness of GeneRide platform

LogicBio Therapeutics, Inc., a genetic medicine company founded to develop safe medicines with lasting therapeutic benefit for children with life-threatening diseases, today announced it will be presenting data on the company's technology and robust preclinical pipeline at the annual meeting of the American Society of Gene & Cell Therapy at the Hilton Chicago, from May 16-19, 2018.

14 May 2018

Scientists discover a mechanism through which HIV determines the fate and function of cells

A stem cell is one with infinite possibilities. So, for decades, scientists have puzzled over how the cell chooses to keep being a stem cell and continue dividing, or specialize into a specific cell type, like a heart or brain cell.

11 May 2018

Findings confirm analytical principle that describes mutational processes and cancer development

When a cell develops into a tumor, something has gone terribly wrong: the uncontrolled growth, invasion of nearby tissues and finally metastasis are the result of many consecutive DNA mutations.

9 May 2018

Bone marrow is an important reservoir for replication and transmission of malaria parasites, shows study

A Plasmodium vivax infection is like an iceberg: It's dangerous, in part, because much of it hides out of view.

8 May 2018

Accelerator Life Science Partners launches new company to develop novel therapy for seizure disorders

Accelerator Life Science Partners (Accelerator), a leading life science investment and management firm, today announced that it has launched Proniras Corporation, a company developing tezampanel for the treatment of a variety of seizure disorders.

27 Apr 2018

Engineered immune cells clear deadly pediatric brain tumor in mice

Engineered human immune cells can vanquish a deadly pediatric brain tumor in a mouse model, a study from the Stanford University School of Medicine has demonstrated.

16 Apr 2018

TradeShow Talks with TIP Biosystems

I'm professor Dieter Trau, and we are at the Analytica at booth, at hall B2, booth 116. The company we are presenting here is TIP Biosystems Pte Ltd.

From Tip Biosystems Pte Ltd 13 Apr 2018

Tradeshow Talks with Analytik Jena

We spoke to Ulrich Krauss, the CEO of Analytik Jena yesterday at analytica 2018.

12 Apr 2018

Tradeshow Talks with Integra

Analytica is a really good event for us to be able to provide face to face interaction with our customers and show them our full range of products all at once.

From INTEGRA Biosciences 11 Apr 2018

Study reveals how apoE4 gene confers risk for Alzheimer's disease in brain cells

Using human brain cells, scientists at the Gladstone Institutes discovered the cause of--and a potential solution for--the primary genetic risk factor for Alzheimer's disease, a gene called apoE4.

9 Apr 2018

Children with autism more likely to be prescribed antipsychotic medication, study finds

A new study by Swansea University has suggested that children with intellectual difficulty or autism are more likely to be given antipsychotic medication from a younger age than those without intellectual disability and have higher rates of hospitalization for depression and for injury and also are at risk of other medical side effects.

4 Apr 2018

IMI Precision Engineering to showcase next-generation life science products at Analytica 2018

IMI Precision Engineering, a world leader in motion and fluid control technologies, is set to showcase its next-generation technologies at one of Europe’s biggest diagnostic and analysis events.