Peptides News and Research

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A new approach to track down cryptic peptides

Almost all cells of the human body present fragments of cellular proteins on their surface, so-called human leukocyte antigens or HLA peptides, which play an important role in the immune response.

23 Jun 2020

Antibodies against prevalent endemic human coronaviruses may provide cross-protection to SARS-CoV-2

Researchers from Qatar have demonstrated that antibody repertoires against endemic human coronaviruses are qualitatively different in children when compared to the general adult population, as well as healthy adult blood bank donors – and they may also provide cross-protection against epidemic/pandemic strains.

23 Jun 2020

SARS-CoV-2 induces broad T cell response in recovering patients

A new study published on the preprint server bioRxiv in June 2020 shows that T cell responses in COVID-19 patients are broader and more robust in severe disease and are explicitly directed against spike, memory, and ORF3a proteins.

23 Jun 2020

Synthetic peptide could be an effective COVID-19 treatment and SARS-CoV-2 vaccine

Ligandal, one of the world’s leading genetic medicine companies, has modeled a synthetic peptide that could be an effective COVID-19 treatment and SARS-CoV-2 vaccine.

22 Jun 2020

PIM profile may help identify proteins expressed by viruses transmitted by Aedes aegypti mosquitos

The life span of the Aedes aegypti mosquito ranges from two to four weeks depending on environmental conditions, during which the female lays about one thousand eggs in water-filled containers close to human environments, because it needs human blood in order to reproduce and to complete its life cycle.

21 Jun 2020

Brain-transportable soy derivate reduces memory degradation in mice

In a study that could help one day give a literal meaning to food for thought, researchers from Kyushu University in Japan have reported that a protein fragment that makes its way into the brain after being ingested can reduce memory degradation in mice treated to simulate Alzheimer's disease.

21 Jun 2020

Crystal structure of SARS-CoV-2 protease-inhibitor in complex with a Chinese herb Shikonin

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus has been spreading rampantly over the whole world, infecting millions of people (over 8.45 million at last count), with over 452,000 deaths, as of June 19, 2020. It causes a broad spectrum of disease manifestations, from asymptomatic disease to severe or even fatal respiratory symptoms.

18 Jun 2020

Cyclosporin study may pave way for treating diseases related to mitochondrial dysfunction

Cyclic peptide molecules of the fungal origin called cyclosporins were discovered in 1970's, and cyclosporin A soon became an important drug due to its immunosuppressive activity.

18 Jun 2020

Lonza and CELLINK collaborate to advance complete 3D cell culture workflows

Lonza and the Swedish company CELLINK have partnered to offer a comprehensive 3-dimensional bioprinting solution designed to optimize and increase access to complete 3D cell culture workflows.

18 Jun 2020

Scientists develop peptides that restore balance in gut bacteria and reverse atherosclerosis

Now, a team of scientists at Scripps Research has developed new molecules that can restore the balance in gut bacteria in the intestines and as a result, lowers cholesterol levels and reverses the narrowing of the arteries, also known as atherosclerosis.

18 Jun 2020

NJIT researchers develop new efficient method for targeted protein analysis

Researchers at New Jersey Institute of Technology in collaboration with Ohio University and Merck & Co. Inc. recently developed a new efficient method for targeted protein analysis -- one they say could speed up processes for disease testing, drug discovery and vaccine development.

17 Jun 2020

Scientists develop molecules that can remodel gut bacteria to a healthier state

Scientists at Scripps Research have developed molecules that can remodel the bacterial population of intestines to a healthier state and they have shown--through experiments in mice--that this reduces cholesterol levels and strongly inhibits the thickened-artery condition known as atherosclerosis.

16 Jun 2020

Study reports structure of enzyme activator for high pathogenic avian influenza

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), causing the current pandemic of COVID-19, is the focus of many investigators seeking to find an effective vaccine or therapeutic. Among the potential targets are various protease enzymes suspected of allowing the virus to gain entry to host cells and establish a successful infection.

16 Jun 2020

High-resolution 3D model reveals a link between Alzheimer's and diabetes

Pathological protein clumps are characteristic of a series of diseases, such as Alzheimer's disease, Parkinson's disease, and type 2 diabetes.

15 Jun 2020

CELLINK collaborates with Lonza to advance complete 3D cell culture workflows

CELLINK has collaborated with Lonza to offer a comprehensive 3-dimensional (3D) bioprinting solution designed to advance complete 3D cell culture workflows.

From CELLINK 12 Jun 2020

A new strategy to combat influenza A and Zika virus

Leuven researchers have deployed synthetic amyloids to trigger protein misfolding as a strategy to combat the influenza A and Zika virus.

9 Jun 2020

Georgia State researcher receives $1.95 million NIH grant to study cause of autoimmunity

Dr. Leszek Ignatowicz, a professor in the Institute for Biomedical Sciences at Georgia State University, has received a five-year, $1.95 million federal grant to study what causes autoimmunity in the human body.

8 Jun 2020

New strategy may facilitate development of multi-epitope peptide vaccine against SARS-CoV-2

By combining T and B lymphocyte analysis with manufacturability heuristic, researchers from the US and Germany proposed a set of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine peptides to use in subsequent animal studies and clinical trials. Their paper is currently available on the bioRxiv preprint server.

7 Jun 2020

George Mason researcher examining the use of Brilacidin for treatment of coronavirus infections

Aarthi Narayanan, Assistant Professor, National Center for Biodefense and Infectious Diseases, received $35,000 from Innovation Pharmaceuticals, Inc., for a project in which she is examining the use of Brilacidin for the treatment of coronavirus infections.

5 Jun 2020

New fluorescent dye may prove useful for biomedical imaging applications

Scientists can monitor biomolecular processes in live tissue by noninvasive optical methods, such as fluorescence imaging.

5 Jun 2020

Peptides News and Research

A new approach to track down cryptic peptides

Antibodies against prevalent endemic human coronaviruses may provide cross-protection to SARS-CoV-2

SARS-CoV-2 induces broad T cell response in recovering patients

Synthetic peptide could be an effective COVID-19 treatment and SARS-CoV-2 vaccine

PIM profile may help identify proteins expressed by viruses transmitted by Aedes aegypti mosquitos

Brain-transportable soy derivate reduces memory degradation in mice

Crystal structure of SARS-CoV-2 protease-inhibitor in complex with a Chinese herb Shikonin

Cyclosporin study may pave way for treating diseases related to mitochondrial dysfunction

Lonza and CELLINK collaborate to advance complete 3D cell culture workflows

Scientists develop peptides that restore balance in gut bacteria and reverse atherosclerosis

NJIT researchers develop new efficient method for targeted protein analysis

Scientists develop molecules that can remodel gut bacteria to a healthier state

Study reports structure of enzyme activator for high pathogenic avian influenza

High-resolution 3D model reveals a link between Alzheimer's and diabetes

CELLINK collaborates with Lonza to advance complete 3D cell culture workflows

A new strategy to combat influenza A and Zika virus

Georgia State researcher receives $1.95 million NIH grant to study cause of autoimmunity

New strategy may facilitate development of multi-epitope peptide vaccine against SARS-CoV-2

George Mason researcher examining the use of Brilacidin for treatment of coronavirus infections

New fluorescent dye may prove useful for biomedical imaging applications

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