Therapeutics News and Research

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TRIMTECH Therapeutics raises $31M seed funding to advance targeted protein degradation pipeline for treatment of neurodegenerative diseases

TRIMTECH Therapeutics raises $31M to enhance its TRIMTAC platform, targeting protein aggregates in neurodegenerative diseases for improved therapeutic outcomes.

From TRIMTECH Therapeutics 7 Mar 2025

Research poses a new explanation for how cancer-fighting drugs attack and destroy tumor cells

Research by UMass Chan Medical School scientists Sharon Cantor, PhD, and Jenna M. Whalen, PhD, poses a new explanation for how cancer-fighting drugs attack and destroy BRCA1 and BRCA2 tumor cells.

7 Mar 2025

Study suggests boosting brain's immune cells could improve Alzheimer's treatment

For more than three decades, scientists have been racing to stop Alzheimer's disease by removing amyloid beta plaques - sticky clumps of toxic protein that accumulate in the brain.

6 Mar 2025

Naturally occurring molecule suppresses appetite and promotes weight loss

A naturally occurring molecule identified by Stanford Medicine researchers appears similar to semaglutide - also known as Ozempic - in suppressing appetite and reducing body weight.

6 Mar 2025

New antibody pair could defeat all SARS-CoV-2 variants

A Stanford-led team has found two antibodies that can work together to defeat all SARS-CoV-2 variants. More research is needed, but the approach could help in the development of treatments to keep pace with evolving viruses.

6 Mar 2025

Insights into mechanosensitive aGPCRs and their role in biological processes and disease

This newly published analysis in Genes & Diseases sheds light on the crucial role of mechanosensitive adhesion G protein-coupled receptors (aGPCRs) in regulating biological processes and their implications in various diseases.

5 Mar 2025

Study sheds light on the role of fibro-adipogenic progenitors in muscle regeneration and degeneration

A recent study has shed new light on the role of fibro-adipogenic progenitors (FAPs) in muscle regeneration, fibrosis, and degeneration.

5 Mar 2025

Macrophage-targeted therapy could enhance cardiac regeneration and myocardial repair

A new review published in Genes & Diseases highlights macrophage-targeted therapy as a promising frontier in cardiac regeneration and myocardial repair.

5 Mar 2025

Exploring the relationship between non-coding RNAs and oxidative stress in cancer progression

A new review article published in Genes & Diseases explores the intricate relationship between non-coding RNAs and oxidative stress in cancer progression shedding new light on the mechanisms that drive tumor development.

5 Mar 2025

New approach to tau protein clearance offers hope for Alzheimer's treatment

USC Stem Cell scientists discover a new way to rid cells of toxic tau protein in a study involving mice and lab-grown human “mini-brains,” known as organoids.

5 Mar 2025

Exploring the role of subventricular zone in neural regeneration, neurodegenerative diseases

This recently published exploration into the subventricular zone (SVZ) highlights its critical role in neural regeneration, neurodegenerative diseases, and glioblastoma multiforme (GBM).

5 Mar 2025

Centauri Therapeutics selects first clinical candidate, for immunotherapeutic treatment of Gram-negative bacterial infections

Centauri Therapeutics Limited (Centauri), an immunotherapy company with a unique and proprietary platform technology applicable across a wide range of therapeutic indications, today announced the selection of its first clinical candidate in the ABX-01 program.

4 Mar 2025

Study uncovers how glucose excreted in the gut converts into beneficial fatty acids

Gut microbes that were thought to feed exclusively on dietary fiber also get fed sugar from our guts, from which they produce short-chain fatty acids that are crucial to many body functions.

4 Mar 2025

Research identifies iron as crucial driver of stroke-related cell death processes

Ischemic stroke continues to rank among the top causes of death and long-term disability globally. While advances in acute treatments like clot retrieval and thrombolysis have improved outcomes, the challenge of managing reperfusion injury—a phase when restored blood flow can ironically harm brain tissue—persists.

4 Mar 2025

Are Allogeneic CAR-Ts the Future of LBCL Cancer Treatment? - Making Safe, Durable & Effective Universal Cell Therapies a Reality

Allogene Therapeutics recently released exciting results from the Phase 1 ALPHA/ALPHA2 trials of the Allogeneic CAR T 'Cemacabtagene Ansegedleucel/ALLO-501' in Relapsed/Refractory Large B-Cell Lymphoma.

From Hanson Wade Group - 7th Allogeneic Cell Therapies Summit 4 Mar 2025

Study provides a comprehensive cellular map of how diabetes disrupts bone immune interactions

When we think of type 2 diabetes, images of heart problems or kidney damage often come to mind. But lurking quietly behind these well-known complications is another serious threat—bone disease.

4 Mar 2025

Breakthrough study sheds light on Pol-theta’s role in DNA repair and cancer

DNA repair proteins act like the body's editors, constantly finding and reversing damage to our genetic code. Researchers have long struggled to understand how cancer cells hijack one of these proteins-called polymerase theta (Pol-theta)-for their own survival.

4 Mar 2025

Study explores gene interactions in Alzheimer's disease across brain regions

Alzheimer's disease (AD), a neurodegenerative disorder marked by amyloid plaque buildup and cognitive decline, remains a challenging condition to understand at the molecular level.

4 Mar 2025

Stem cell therapy for cornea injuries demonstrates remarkable results in clinical trial

An expanded clinical trial that tested a groundbreaking, experimental stem cell treatment for blinding cornea injuries found the treatment was feasible and safe in 14 patients who were treated and followed for 18 months, and there was a high proportion of complete or partial success.

4 Mar 2025

Targeting mitochondrial DNA integrity for cardiac protection after injury

Maintaining mitochondrial DNA (mtDNA) integrity is crucial for cardiomyocyte function, and its disruption plays a significant role in ischemia/reperfusion (I/R) injury.

4 Mar 2025

Therapeutics News and Research

TRIMTECH Therapeutics raises $31M seed funding to advance targeted protein degradation pipeline for treatment of neurodegenerative diseases

Research poses a new explanation for how cancer-fighting drugs attack and destroy tumor cells

Study suggests boosting brain's immune cells could improve Alzheimer's treatment

Naturally occurring molecule suppresses appetite and promotes weight loss

New antibody pair could defeat all SARS-CoV-2 variants

Insights into mechanosensitive aGPCRs and their role in biological processes and disease

Study sheds light on the role of fibro-adipogenic progenitors in muscle regeneration and degeneration

Macrophage-targeted therapy could enhance cardiac regeneration and myocardial repair

Exploring the relationship between non-coding RNAs and oxidative stress in cancer progression

New approach to tau protein clearance offers hope for Alzheimer's treatment

Exploring the role of subventricular zone in neural regeneration, neurodegenerative diseases

Centauri Therapeutics selects first clinical candidate, for immunotherapeutic treatment of Gram-negative bacterial infections

Study uncovers how glucose excreted in the gut converts into beneficial fatty acids

Research identifies iron as crucial driver of stroke-related cell death processes

Are Allogeneic CAR-Ts the Future of LBCL Cancer Treatment? - Making Safe, Durable & Effective Universal Cell Therapies a Reality

Study provides a comprehensive cellular map of how diabetes disrupts bone immune interactions

Breakthrough study sheds light on Pol-theta’s role in DNA repair and cancer

Study explores gene interactions in Alzheimer's disease across brain regions

Stem cell therapy for cornea injuries demonstrates remarkable results in clinical trial

Targeting mitochondrial DNA integrity for cardiac protection after injury

Understanding the DNA Damage Response in Innate Immunity eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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