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Study uncovers genetic cause of a novel developmental epilepsy syndrome

Neurodevelopmental disorders (NDD) encompass highly prevalent conditions such as autism and epilepsy, with cognitive disabilities alone affecting 1-3% of the global population.

16 Dec 2022

mRNA vaccine methodologies: Production, value and spectrometer use

To be decided by the editor

From Thermo Fisher Scientific – Pharmaceutical and Biopharmaceutical Solutions 16 Dec 2022

Imaging method yields highly accurate and precise values of radionuclide organ uptake

Patients with cancer that has spread to the bone are sometimes treated with alpha particle radiation therapy that is delivered into or very close to the tumor.

16 Dec 2022

mRNA-FISH for the detection of viral RNA in SARS-CoV-2 infected cells and the determination of the kinetics of early RNA replication

Researchers evaluated the early replication kinetics of SARS-CoV-2.

15 Dec 2022

How is the host’s m6A mRNA profile affected during SARS-CoV-2 infection?

Researchers observed that SARS-CoV-2 infection results in loss of N6-methyladenosine modification in cellular RNAs.

15 Dec 2022

Study: 9% of adolescents report experiencing both persistent pain and suicidality

Nearly one in 10 young people are experiencing both persistent physical pain and suicidal feelings, according to a new paper from researchers from the University of Oxford, Cambridge, Oslo (Norway), King's College London, and the Parc Sanitari Sant Joan de Deu (Spain).

14 Dec 2022

New report provides a broad view of the global burden of cardiovascular disease

Cardiovascular disease (CVD) remains the leading cause of death across the globe, according to a new "almanac"-style special issue of the Journal of the American College of Cardiology.

13 Dec 2022

Study: Only 30% of people with neuroendocrine tumors consider living longer as top priority

New research from cancer research and treatment organization City of Hope in the December 2022 issue of JNCCN - Journal of the National Comprehensive Cancer Network finds that only 30% of patients with advanced neuroendocrine tumors (NETs) say their top goal for treatment is living longer.

12 Dec 2022

GOSH delivers world-first base-edited cell therapy for a patient with relapsed T cell leukemia

A patient with relapsed T cell leukemia has been given base-edited T-cells in a world-first use of a base-edited cell therapy, in a 'bench-to-bedside' collaboration between UCL and Great Ormond Street Hospital for Children (GOSH).

12 Dec 2022

New project aims to address the vast data-related problems in cancer research

The National Cancer Institute has awarded $10.5 million to the Division of Biostatistics at the Department of Population and Public Health Sciences at the Keck School of Medicine of USC.

6 Dec 2022

Research reveals a novel viral strategy in modulating stress granule formation to promote virus infection

Researchers illustrated a novel strategy likely employed by viruses to promote infection.

6 Dec 2022

Researchers develop a polyvalent lipid nanoparticle mRNA vaccine against Monkeypox virus

Researchers developed an mRNA technology-based vaccine candidate against the monkeypox virus and evaluated its immunogenicity in animal models.

5 Dec 2022

Researchers develop potent yet low-inflammatory mRNA cancer vaccine vectors

Lipid nanoparticle (LNP)-based messenger ribonucleic acid (mRNA) vaccines have recently emerged as a promising strategy for the prevention and treatment of cancers, as well as infectious diseases.

4 Dec 2022

Using cationic nanonmaterials to target visceral adiposity

Researchers have long been working on how to treat obesity, a serious condition that can lead to hypertension, diabetes, chronic inflammation, and cardiovascular diseases.

1 Dec 2022

Study finds a number of barriers to accessing interpreting services in primary care

People who do not speak English well often ask friends and family to translate for them when accessing their GP practice, finds a new study from the University of Surrey.

30 Nov 2022

UQ scientist receives a Churchill Fellowship to expand spinal cord injury research

A University of Queensland scientist is set expand his research into finding new treatments for spinal cord injury after being awarded a 2022 Churchill Fellowship.

28 Nov 2022

New microfluidic Organ Chip platform replicates the human vaginal tissue microenvironment

The human microbiome has been a hot topic over the last decade, with research pointing to disrupted bacterial communities as culprits for a host of maladies including irritable bowel syndrome, eczema, and autoimmune diseases.

28 Nov 2022

Exploring synthetic engineering of bacteriophages

In a new study, researchers demonstrated biological bacteriophage containment and synthetic engineering.

24 Nov 2022

Scientists develop RNA-targeting strategy to repair genetic cause of ALS and dementia

Scientists at UF Scripps Biomedical Research have developed a potential medicine for a leading cause of ALS and dementia that works by eliminating disease-causing segments of RNA. The

22 Nov 2022

New EULAR recommendations for screening and treating infections in AIIRD patients

It is already known that people who are immunocompromised are more prone to infections. Chronic and opportunistic infections are often found in people with an AIIRD, and may be linked to some of the immunosuppressive and immunomodulatory treatments used to treat these rheumatic diseases.