Therapy News and Research

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Individuals with high BMI and LDL cholesterol are at increased risk of COVID-19

A new study led by researchers at Queen Mary University of London uses a novel approach to investigate the effects of cardiovascular risk factors on the risk of COVID-19 infection.

16 Nov 2020

New antibody fragment helps reduce Aβ levels in old mice with Alzheimer’s disease

Alzheimer's disease is the most common dementia worldwide and it is characterized by learning impairment, memory loss, disorientation, and anxiety, among other behavioral and psychological symptoms.

16 Nov 2020

New tool predicts which cancer patients will respond positively to immunotherapy

An international group led by Dr Banafshe Larijani, an Ikerbasque researcher seconded to the Biofisika Institute (UPV/EHU-University of the Basque Country, CSIC), has developed a new diagnostic method making it possible to accurately predict which cancer patients will respond positively to immunotherapy.

16 Nov 2020

Additional imaging tests can detect cause of heart attack in women with no major artery blockage

Diagnostic imaging techniques were able to find the underlying cause of heart attack in many women who had no major artery blockage, according to late- breaking research presented today at the American Heart Association's Scientific Sessions 2020.

16 Nov 2020

Antiviral immune response is suppressed in COVID-19 patients compared to flu patients

Rather than life-threatening hyperinflammation, most adults with moderate-to-severe COVID-19 have a suppressed viral immune response when compared to adults with another viral respiratory infection, influenza. St. Jude Children's Research Hospital and Washington University School of Medicine in St. Louis led research that suggests most COVID-19 patients are not candidates for treatment with steroids such as dexamethasone.

16 Nov 2020

New drug reduces LDL cholesterol in patients with severe hypercholesterolemia

The investigational drug evinacumab reduced low-density lipoprotein (LDL) cholesterol--the so-called "bad" cholesterol--by 50 percent in patients with severe hypercholesterolemia whose condition is resistant to standard treatments, a phase 2 study from the Icahn School of Medicine of Mount Sinai and other global academic sites has found.

16 Nov 2020

Study confirms link between gut microbiota and Alzheimer's disease

Alzheimer's disease is the most common cause of dementia. Still incurable, it directly affects nearly one million people in Europe, and indirectly millions of family members as well as society as a whole.

16 Nov 2020

Study reveals 3D structure of key phage component in atomic resolution

Given that phages are able to destroy bacteria, they are of particular interest to science. Basic researchers from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) in Berlin are especially interested in the tube used by phages to implant their DNA into bacteria.

16 Nov 2020

Researchers use aerosolized molecules to shut down proteins generated by coronavirus

Researchers at Georgetown University Medical Center have successfully used molecules comprised of small strands of RNA to shut down the production of destructive proteins generated by the COVID-19 virus.

16 Nov 2020

New data highlights safety concerns on rAAV vectors used in gene therapy

New data highlight safety concerns for the replication of recombinant adeno-associated viral (rAAV) vectors commonly used in gene therapy.

16 Nov 2020

People taking placebo pills and statins experienced similar side effects, shows study

People taking dummy pills and statins experienced similar side effects in a new study.

15 Nov 2020

MTT procedure improves gastrointestinal, behavioral symptoms in ASD children

According to the Centers for Disease Research, 1 in 54 children is diagnosed with autism spectrum disorder (ASD) each year, and the number has been rising.

15 Nov 2020

Drugs targeting neutrophils could reduce ARDS in severe COVID-19

Scientists in Taiwan recently published a report on their use of anti-neutrophil strategies to treat acute respiratory distress syndrome (ARDS) – a life-threatening condition that can arise in critical COVID-19 cases – in the journal Frontiers in Pediatrics.

15 Nov 2020

Polypill plus aspirin and polypill alone reduced cardiovascular disease risk

A single, daily pill combining blood pressure and cholesterol medications, along with the addition of a daily dose of aspirin, reduced cardiovascular disease events in people at risk for heart disease, according to late-breaking research presented today in a late-breaking clinical trial presentation at the American Heart Association's Scientific Sessions 2020.

15 Nov 2020

New medication may reduce risk for heart failure-related events in people with chronic heart failure

Omecamtiv mecarbil, a new, investigational heart medication, reduced the risk of heart failure-related events in patients with heart failure with reduced ejection fraction, according to late-breaking research presented today at the American Heart Association's Scientific Sessions 2020.

15 Nov 2020

Intravenous iron replacement reduces risk of recurrent hospitalization in patients with heart failure

Patients who were hospitalized with acute heart failure and had iron deficiency were less likely to return to the hospital if given intravenous iron replacement, according to late-breaking research presented today at the American Heart Association's Scientific Sessions 2020.

15 Nov 2020

Inhaled nebulized interferon beta-1a (SNG001) helps COVID-19 patients recovers

Now, a team of researchers at the Synairgen Research, Southampton General Hospital, Southampton, United Kingdom, has found that inhaled nebulized interferon beta-1a (SNG001), a drug used for multiple sclerosis, helped COVID-19 patients have greater odds of improvement and recovery from SARS-CoV-2 infection.

15 Nov 2020

Study helps quantify racial and ethnic disparities in pediatric diabetes treatment

Type 1 diabetes (T1D) is the third most common pediatric chronic disease in the United States, and the risk of the disease has risen sharply in non-Hispanic Black (NHB) children in the last 20 years, data show.

12 Nov 2020

JNCCN: Cost-effectiveness of olaparib for metastatic pancreatic cancer

Studies have shown that utilizing a PARP inhibitor in the management of patients with metastatic pancreatic cancer who harbor BRCA 1/2 mutations is clinically beneficial.

12 Nov 2020

Convalescent plasma in COVID-19 can be effective, especially early in disease

A team of researchers in the United States have conducted an extensive literature review looking at the usage of convalescent plasma from recovered COVID-19 patients to treat those with an impaired immune system. Their study, titled “Therapeutic use of convalescent plasma in COVID-19 patients with immunodeficiency: A systematic review,” has been released on medRxiv*, the preprint server.

12 Nov 2020

Therapy News and Research

Individuals with high BMI and LDL cholesterol are at increased risk of COVID-19

New antibody fragment helps reduce Aβ levels in old mice with Alzheimer’s disease

New tool predicts which cancer patients will respond positively to immunotherapy

Additional imaging tests can detect cause of heart attack in women with no major artery blockage

Antiviral immune response is suppressed in COVID-19 patients compared to flu patients

New drug reduces LDL cholesterol in patients with severe hypercholesterolemia

Study confirms link between gut microbiota and Alzheimer's disease

Study reveals 3D structure of key phage component in atomic resolution

Researchers use aerosolized molecules to shut down proteins generated by coronavirus

New data highlights safety concerns on rAAV vectors used in gene therapy

People taking placebo pills and statins experienced similar side effects, shows study

MTT procedure improves gastrointestinal, behavioral symptoms in ASD children

Drugs targeting neutrophils could reduce ARDS in severe COVID-19

Polypill plus aspirin and polypill alone reduced cardiovascular disease risk

New medication may reduce risk for heart failure-related events in people with chronic heart failure

Intravenous iron replacement reduces risk of recurrent hospitalization in patients with heart failure

Inhaled nebulized interferon beta-1a (SNG001) helps COVID-19 patients recovers

Study helps quantify racial and ethnic disparities in pediatric diabetes treatment

JNCCN: Cost-effectiveness of olaparib for metastatic pancreatic cancer

Convalescent plasma in COVID-19 can be effective, especially early in disease

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