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European scientists set up new therapeutic approaches to tackle gene defects

On 15th April is the 1st International Pompe Disease Day, a campaign to raise awareness of this rare but severe gene defect. Pompe Disease is only one of more than 40 metabolic disorders that mainly affect children under the age of 10, often with devastating consequences.

15 Apr 2014

Lin28 gene may hold clues to regeneration of damaged kidneys in adults

Nearly one-third of cases of Wilms tumor, a pediatric cancer of the kidney, are linked to a gene called Lin28, according to research from Boston Children's Hospital. Mice engineered to express Lin28 in their kidneys developed Wilms tumor, which regressed when Lin28 was withdrawn, indicating that strategies aimed at blocking or deactivating the gene hold therapeutic promise for children with Wilms.

15 Apr 2014

Scientists receive grant from Biogen Idec to study everyday activities in MS using actual reality

John DeLuca, PhD, and Yael Goverover, PhD, OT, have received a grant from Biogen Idec to study how persons with multiple sclerosis (MS) perform everyday life tasks. The grant, entitled "The Use of Actual Reality to Measure Everyday Life Functional Activity in Multiple Sclerosis" provides financial support to conduct this research.

15 Apr 2014

Radiation plus hormones offers best outcomes for localised prostate cancer

The combination of radiotherapy and androgen deprivation therapy is more effective than radiotherapy alone for preventing disease recurrence in men with localised prostate cancer, according to research findings presented at the European Society for Radiotherapy and Oncology 33rd annual congress in Vienna, Austria.

14 Apr 2014

Three-gene test may aid earlier lung cancer detection

Methylation of three genes may help with the early diagnosis of non-small-cell lung cancer, research suggests.

14 Apr 2014

Two candidate mTOR therapy biomarkers identified in RCC

Two genes, TSC1 and MTOR, warrant further investigation as biomarkers for treatment benefit with rapalogs in patients with renal cell carcinoma, indicate study results published in Clinical Cancer Research.

14 Apr 2014

Researcher at Fox Chase Cancer Center wins a new Cytation™ 3 Cell Imaging Multi-Mode Reader in BioTek's "Think Possible" Application Contest

BioTek congratulates Dr. Jeff Peterson of the Fox Chase Cancer Center in Pennsylvania for winning a new Cytation™ 3 Cell Imaging Multi-Mode Reader in BioTek's "Think Possible" Application Contest. Entrants were judged on a short essay that they submitted, detailing the application that they think is possible for their specific research using the Cytation 3. As an Associate Professor, Dr. Peterson studies chemical biology and kinase signaling in cancer.

14 Apr 2014

Bio-Rad Laboratories buys GnuBIO

GnuBIO, a privately-held life sciences company that has developed a droplet-based DNA sequencing technology, today announced that it was acquired by Bio-Rad Laboratories, Inc. With this acquisition, Bio-Rad will expand its Digital Biology Center and establish a research and development site in Cambridge, Massachusetts.

11 Apr 2014

New patient-centered, team-based approach may help surgical decision making for sick, elderly patients

Surgical decision making for sick, elderly patients should be orchestrated by a multidisciplinary team, including the patient, his or her family, the surgeon, primary care physician, nurses and non-clinicians, such as social workers, advocates Laurent G. Glance, M.D., in a perspective piece published in the New England Journal of Medicine.

11 Apr 2014

1/4 human tumor exist genetic polymorphisms linked with increased risk of cancer

In 10% of human tumors there is a family history of hereditary disease associated with mutations in identified genes. The best examples are the cases of polyps in the large intestine associated with the APC gene and breast cancer associated with BRCA1 and BRCA2 genes.

11 Apr 2014

Research!America and partner organizations launch national voter education initiative

Two-thirds of Americans (66%) say it's important for candidates running for office to assign a high priority to funding medical research, according to America Speaks, Volume 14, a compilation of key questions from public opinion polls commissioned by Research!America.

11 Apr 2014

Study confirms neurobiological origin of attention-deficit disorder

A study, carried out on mice, has just confirmed the neurobiological origin of attention-deficit disorder (ADD), a syndrome whose causes are poorly understood. Researchers from CNRS, the University of Strasbourg and INSERM1 have identified a cerebral structure, the superior colliculus, where hyperstimulation causes behavior modifications similar to those of some patients who suffer from ADD.

11 Apr 2014

Tau Therapeutics presents data of T-type calcium channel inhibitors in treatment of pancreatic cancer

Tau Therapeutics LLC announced today that its academic collaborator, University of Virginia Professor Todd Bauer, MD, presented data at the 105th Annual Meeting of the American Association for Cancer Research (AACR), the premier cancer research event held in San Diego, California from April 5-9.

11 Apr 2014

New paper calls for increase in geographically targeted prevention, treatment for HIV-infected people

In U.S. cities, it's not just what you do, but also your address that can determine whether you will get HIV and whether you will survive. A new paper in the American Journal of Public Health illustrates the effects of that geographic disparity - which tracks closely with race and poverty - and calls for an increase in geographically targeted prevention and treatment efforts.

11 Apr 2014

Study suggests nestin+ cholinergic neurons may have closer connection to olfactory bulb neurons

Dr. Yuhong Zhao and co-workers from Sun Yat-sen University in China explored the projection of nestin+ neurons to the olfactory bulb and the time course of nestin+ neurons in the medial septum-diagonal band of Broca in adult rats during injury recovery after olfactory nerve transection.

11 Apr 2014

Researchers uncover new aspect of autism

A team of researchers from the University of California, San Diego School of Medicine and the Center for Cancer Systems Biology at the Dana-Farber Cancer Institute has uncovered a new aspect of autism, revealing that proteins involved in autism interact with many more partners than previously known. These interactions had not been detected earlier because they involve alternatively spliced forms of autism genes found in the brain.

11 Apr 2014

PolyTherics extends ThioBridge antibody drug conjugate collaboration with MacroGenics

PolyTherics Limited, a provider of technologies and services to enable the development of better biopharmaceuticals, today announced an extension to its ThioBridge antibody drug conjugate ("ADC") collaboration with MacroGenics Inc, a US biotechnology company developing innovative medicines utilizing its next generation antibody technologies.

11 Apr 2014

Scientists shed light on runny nose

Scientists at the University of Colorado School of Medicine have shed light on one of the most common of ailments - the runny nose.

11 Apr 2014

Highlights: Va. mental health care task force; pharmacist duties in N.C.; nurse practitioners in Conn.

A selection of health policy stories from Virginia, North Carolina, New York, Connecticut, Minnesota, Florida, Iowa and Oregon.

11 Apr 2014

Researchers discover tumor suppressor gene folliculin essential to normal lung function in BHD patients

Researchers at Penn Medicine have discovered that the tumor suppressor gene folliculin (FLCN) is essential to normal lung function in patients with the rare disease Birt-Hogg-Dube (BHD) syndrome, a genetic disorder that affects the lungs, skin and kidneys.

11 Apr 2014

Research News and Research

European scientists set up new therapeutic approaches to tackle gene defects

Lin28 gene may hold clues to regeneration of damaged kidneys in adults

Scientists receive grant from Biogen Idec to study everyday activities in MS using actual reality

Radiation plus hormones offers best outcomes for localised prostate cancer

Three-gene test may aid earlier lung cancer detection

Two candidate mTOR therapy biomarkers identified in RCC

Researcher at Fox Chase Cancer Center wins a new Cytation™ 3 Cell Imaging Multi-Mode Reader in BioTek's "Think Possible" Application Contest

Bio-Rad Laboratories buys GnuBIO

New patient-centered, team-based approach may help surgical decision making for sick, elderly patients

1/4 human tumor exist genetic polymorphisms linked with increased risk of cancer

Research!America and partner organizations launch national voter education initiative

Study confirms neurobiological origin of attention-deficit disorder

Tau Therapeutics presents data of T-type calcium channel inhibitors in treatment of pancreatic cancer

New paper calls for increase in geographically targeted prevention, treatment for HIV-infected people

Study suggests nestin+ cholinergic neurons may have closer connection to olfactory bulb neurons

Researchers uncover new aspect of autism

PolyTherics extends ThioBridge antibody drug conjugate collaboration with MacroGenics

Scientists shed light on runny nose

Highlights: Va. mental health care task force; pharmacist duties in N.C.; nurse practitioners in Conn.

Researchers discover tumor suppressor gene folliculin essential to normal lung function in BHD patients

Industry Focus eBook - Life Science Microscopy (2nd Edition) eBook

Latest eBooks

Editorial Focus eBook - Proteomics (2nd Edition)

Industry Focus eBook - Life Science Microscopy (2nd Edition)

BFEB: Advances in microplate-based assays and analysis

Biologics stability screening toolkit: Three practical workflows for accelerating formulation development

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy