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Ceftolozane/tazobactam combo broadens the range of antibiotic therapy, but shows no hint of added benefit

The combination of ceftolozane with tazobactam broadens the range of antibiotic therapy in adults with severe infections of the lungs, the urinary tract, the renal pelvis and the abdominal cavity.

2 Jul 2020

Study shows early promise of using laughing gas to relieve veterans' PTSD symptoms

For military veterans suffering from post-traumatic stress disorder (PTSD), symptoms such as anxiety, anger and depression can have a devastating impact on their health, daily routine, relationships and overall quality of life.

2 Jul 2020

Study identifies a promising way to delay the onset of Alzheimer's disease

Currently we are facing a dementia epidemic, estimations showing that by 2050 approximately 131 million people will be affected. Every 7 seconds a patient is diagnosed worldwide.

2 Jul 2020

Researchers develop new electronic tool to prevent dangerous polypharmacy

We have an aging population. As the population ages, the prevalence of chronic disease increases. As a result, more and more drugs are prescribed.

2 Jul 2020

Developing Vaccines and Therapeutics by Exploiting Structure in Spherical Nucleic Acids

An interview discussing the use of spherical nucleic acids (SNAs) and what they show about the importance of structure in pharmaceutical development.

From Pittcon 2 Jul 2020

Novel method shows how cell membranes are damaged by 'Parkinson's protein'

In sufferers of Parkinson's disease, clumps of α-synuclein (alpha-synuclein), sometimes known as the 'Parkinson's protein', are found in the brain.

2 Jul 2020

Structure of the full SARS-CoV-2 RNA genome in infected cells

The current COVID-19 pandemic caused by a single-stranded RNA virus, thought to have jumped across species barriers to infect humans, has spread rapidly across the globe infecting over 10 million individuals. The virus, now known as the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is the causative agent of COVID-19 disease. COVID-19 disease is a respiratory illness where symptoms can range from very mild to severe and include fever, coughing, a sore throat, and shortness of breath.

2 Jul 2020

Repurposed drug for acute lung injury in COVID-19

Now, a new study addresses the possible use of an FDA-approved monoclonal antibody, called fostamatinib, a spleen tyrosine kinase inhibitor (SYK), to reduce the levels of mucin-1, a molecule associated with acute lung injury and acute respiratory distress syndrome (ARDS). People who have severe COVID-19 disease may develop ARDS.

2 Jul 2020

Scientists find coronavirus' Achilles' heel

A team of scientists at the University of California San Francisco has found out how SARS-CoV-2, the virus that causes the coronavirus disease (COVID-19) invades proteins in the cells that serve as master regulators of key cellular processes.

1 Jul 2020

Extended culture of human pancreatic slices as a model to study regeneration of beta cells

Scientists from the Diabetes Research Institute (DRI) at the University of Miami Miller School of Medicine have developed a method allowing for the long-term culture of "pancreatic slices" to study the regeneration of the human pancreas in real time.

1 Jul 2020

More than one-third of excess deaths in pandemic's early months linked to other causes

Since COVID-19's spread to the United States earlier this year, death rates in the U.S. have risen significantly. But deaths attributed to COVID-19 only account for about two-thirds of the increase in March and April, according to a study published Wednesday in the Journal of the American Medical Association.

1 Jul 2020

Scientists find a simpler approach to generate sensory cells of the inner ear

Scientists from the USC Stem Cell laboratories of Neil Segil and Justin Ichida are whispering the secrets of a simpler way to generate the sensory cells of the inner ear.

1 Jul 2020

Common asthma drug may offer potential as treatment for Alzheimer's disease

A new study reveals that the common asthma drug salbutamol may offer potential as a treatment for Alzheimer's disease.

1 Jul 2020

New program aims to prevent prescription drug use among high school students

George Mason University Professor Dr. Kenneth W. Griffin, received $156,581 from National Health Promotion Associates for a project aimed at preventing prescription drug use among high school students.

1 Jul 2020

Study sheds light on selective neuronal vulnerability in Alzheimer’s disease

When Alzheimer's disease strikes, the entire brain doesn't crumble at once. Instead the mind unravels like grim clockwork, beginning with the telltale degradation of a group of brain cells in the entorhinal cortex.

1 Jul 2020

Novel drug could protect the brain during and after stroke

Neuroscientists at the University of Pittsburgh Brain Institute have identified a novel drug that could protect the brain during and after a stroke.

1 Jul 2020

Researchers develop a potential treatment approach for Pelizaeus-Merzbacher disease

A team led by Case Western Reserve University medical researchers has developed a potential treatment method for Pelizaeus-Merzbacher disease (PMD), a fatal neurological disorder that produces severe movement, motor and cognitive dysfunction in children.

1 Jul 2020