Abdominal Pain News and Research

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Abdominal pain is traditionally described by its chronicity (acute or chronic), its progression over time, its nature (sharp, dull, colicky), its distribution (by various methods, such as abdominal quadrant (left upper quadrant, left lower quadrant, right upper quadrant, right lower quadrant) or other methods that divide the abdomen into nine sections), and by characterization of the factors that make it worse, or alleviate it.

ViroPharma commences VP 20621 Phase 2 study for prevention of recurrent Clostridium difficile infection

ViroPharma Incorporated today announced initiation of a Phase 2 dose-ranging clinical study to evaluate the safety, tolerability, and efficacy of VP 20621 for prevention of recurrence of Clostridium difficile infection (CDI) in adults previously treated for CDI.

20 May 2011

Simple home-based colon cancer screening test can prevent many unnecessary deaths in Canada

Use of a simple, at-home screening test by Canadians can prevent many unnecessary colorectal cancer deaths, according to a special report about colorectal cancer in Canadian Cancer Statistics 2011 released today by the Canadian Cancer Society, in collaboration with the Public Health Agency of Canada and Statistics Canada.

19 May 2011

Pfizer's axitinib Phase 3 trial in advanced renal cell carcinoma meets primary endpoints

Pfizer Inc. today announced data from the pivotal Phase 3 AXIS 1032 trial, showing that in patients with previously treated advanced renal cell carcinoma, axitinib significantly extended progression-free survival at the 47th Annual American Society of Clinical Oncology meeting in Chicago from June 3-7, 2011.

19 May 2011

Irritable Bowel Syndrome linked to bacterial overgrowth, food poisoning

Cedars-Sinai researchers have reported two advances in the understanding of Irritable Bowel Syndrome, the most common gastrointestinal disorder in the United States, affecting an estimated 30 million people.

12 May 2011

Study finds strong link between live birth rates and number of eggs retrieved in one IVF cycle

An analysis of over 400,000 IVF cycles in the UK has shown that doctors should aim to retrieve around 15 eggs from a woman's ovaries in a single cycle in order to have the best chance of achieving a live birth after assisted reproduction technology.

11 May 2011

Study confirms LcS-fermented milk reduces fever linked with acute norovirus gastroenteritis

The Laboratory Department for Probiotics Research at the Juntendo University Graduate School of Medicine studied supplementation of probiotic fermented milk containing Lactobacillus casei strain Shirota in elderly individuals living at a nursing home and confirmed reduced fever associated with acute norovirus gastroenteritis.

10 May 2011

Abbott, Sucampo present lubiprostone phase 3 trial data in Japanese CIC at DDW 2011

Sucampo Pharmaceuticals, Inc. and Abbott today reported data from a phase 3 clinical efficacy trial in 124 Japanese chronic idiopathic constipation patients as well as from a phase 3 long-term safety trial in an additional 209 Japanese CIC patients.

10 May 2011

FDA approves Afinitor for treatment of progressive neuroendocrine tumors in the pancreas

On Thursday, the U.S. Food and Drug Administration approved Afinitor (everolimus) to treat patients with progressive neuroendocrine tumors located in the pancreas (PNET) that cannot be removed by surgery or that have spread to other parts of the body (metastatic).

7 May 2011

H. pylori DNA may help treat severe colitis

DNA from Helicobacter pylori, a common stomach bacteria, minimizes the effects of colitis in mice, according to a new study by University of Michigan Medical School scientists.

6 May 2011

FDA approves Novartis' Afinitor tablets for pancreatic NET treatment

Novartis Pharmaceuticals Corporation announced today that the US Food and Drug Administration approved Afinitor tablets for the treatment of progressive neuroendocrine tumors of pancreatic origin in patients with unresectable, locally advanced or metastatic disease.

6 May 2011

Fecal transplant procedures performed at Sinai Hospital

Sudhir Dutta, M.D., head of the Division of Gastroenterology at Sinai Hospital, performed fecal transplant procedures for two patients with severe clostridium difficile (C. difficile) colitis that did not respond to routine antibiotic and other treatments. C. difficile causes symptoms ranging from mild diarrhea to more serious, sometimes life threatening colon inflammation.

5 May 2011

Pfizer’s Revatio receives European Commission approval for pediatric treatment of pulmonary arterial hypertension

Pfizer Inc. announced that Revatio (sildenafil citrate) has been approved by the European Commission for the treatment of pediatric patients aged 1 to 17 years old with pulmonary arterial hypertension. Efficacy in terms of improvement of exercise capacity or pulmonary hemodynamics has been shown in primary pulmonary hypertension and pulmonary hypertension associated with congenital heart disease.

5 May 2011

Lead investigator to discuss growing impact of AFib on US health care costs and resources

Two studies to be presented this week address the often-overlooked costs associated with atrial fibrillation, the most common form of cardiac arrhythmia.

5 May 2011

AstraZeneca receives FDA approval for NEXIUM I.V. to treat GERD with erosive esophagitis

AstraZeneca announced today that the U.S. Food and Drug Administration has approved the use of NEXIUM I.V. for Injection for children ages greater than 1 month old for the short-term treatment of gastroesophageal reflux disease with erosive esophagitis when oral therapy is not possible or appropriate.

3 May 2011

Bioniche Life Sciences opens new livestock vaccine manufacturing facility

Bioniche Life Sciences Inc., a research-based, technology-driven Canadian biopharmaceutical company, today officially opened its new Animal Health and Food Safety Vaccine Manufacturing Centre at its corporate headquarters in Belleville, Ontario, Canada.

30 Apr 2011

ED providers need to assess STI risks in adolescents: Instructor of pediatrics

All adolescent females who show up in the emergency department complaining primarily of lower abdominal pain and/or urinary or genital symptoms should be tested for sexually transmitted infections, according to the authors of a study to be presented Saturday, April 30, at the Pediatric Academic Societies annual meeting in Denver.

30 Apr 2011

Antiviral Drugs Advisory Committee recommends FDA to approve telaprevir for hepatitis C

Vertex Pharmaceuticals Incorporated announced that the Antiviral Drugs Advisory Committee to the U.S. Food and Drug Administration voted unanimously to recommend FDA approval of telaprevir for people with genotype 1 chronic hepatitis C.

29 Apr 2011

More women using ‘morning after’ pill

Figures have revealed that the rate of women using emergency contraception in 2006-08 more than doubled, compared with the rate in the previous four to six years, before the pills were approved for use without a prescription. This comes from a study from the Guttmacher Institute.

29 Apr 2011

Nausea and vomiting are most feared of all chemotherapy-related side effects

PediatRx, Inc. today commented on studies which reveal that chemotherapy-induced nausea and vomiting is one of the most feared of all chemotherapy-related side effects. The fear of nausea and subsequent vomiting is many times so significant that patients can develop a condition known as 'anticipatory' nausea, where the patient becomes nauseous primarily as a result of the fear of becoming nauseous.

25 Apr 2011

AstraZeneca announces U.S. availability of vandetanib for rare medullary thyroid cancer

AstraZeneca today announced that the orphan drug vandetanib is now available to U.S. patients for the treatment of medullary thyroid cancer that cannot be removed by surgery or that has spread to other parts of the body.

25 Apr 2011

Abdominal Pain News and Research

Further Reading

ViroPharma commences VP 20621 Phase 2 study for prevention of recurrent Clostridium difficile infection

Simple home-based colon cancer screening test can prevent many unnecessary deaths in Canada

Pfizer's axitinib Phase 3 trial in advanced renal cell carcinoma meets primary endpoints

Irritable Bowel Syndrome linked to bacterial overgrowth, food poisoning

Study finds strong link between live birth rates and number of eggs retrieved in one IVF cycle

Study confirms LcS-fermented milk reduces fever linked with acute norovirus gastroenteritis

Abbott, Sucampo present lubiprostone phase 3 trial data in Japanese CIC at DDW 2011

FDA approves Afinitor for treatment of progressive neuroendocrine tumors in the pancreas

H. pylori DNA may help treat severe colitis

FDA approves Novartis' Afinitor tablets for pancreatic NET treatment

Fecal transplant procedures performed at Sinai Hospital

Pfizer’s Revatio receives European Commission approval for pediatric treatment of pulmonary arterial hypertension

Lead investigator to discuss growing impact of AFib on US health care costs and resources

AstraZeneca receives FDA approval for NEXIUM I.V. to treat GERD with erosive esophagitis

Bioniche Life Sciences opens new livestock vaccine manufacturing facility

ED providers need to assess STI risks in adolescents: Instructor of pediatrics

Antiviral Drugs Advisory Committee recommends FDA to approve telaprevir for hepatitis C

More women using ‘morning after’ pill

Nausea and vomiting are most feared of all chemotherapy-related side effects

AstraZeneca announces U.S. availability of vandetanib for rare medullary thyroid cancer

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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