Bioinformatics News and Research

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Bioinformatics is the application of information techniques for the storage, retrieval, and analysis of large quantities of biological data.

Inhibition of a protease could improve the treatment of IBD, study shows

Scientists at the Centro Nacional de Investigaciones Cardiovasculares and the Centro de Investigaciones Biológicas of the Consejo Superior de Investigaciones Científicas have identified the protease MT1-MMP as a possible future target for drugs to treat inflammatory bowel disease.

3 Dec 2019

Study finds autism-related genetic mutations in aging brains of Alzheimer's patients

Researchers believe that autism is caused by mutations that occur sporadically in the egg or sperm or during pregnancy.

26 Nov 2019

Wound healing events in mucous tissues could guard against AIDS

Wound healing events in mucous tissues during early infection by Simian Immunodeficiency Virus, or SIV, guard some primate species against developing AIDS, a recent study has learned.

21 Nov 2019

New technology may offer alternative means of profiling tissues

Current cancer treatment courses often begin with tissue biopsies. Biopsies, however, which involve the physical resection of a small tissue sample, can lead to localized tissue injury, bleeding, inflammation, and stress, as well as increased risk of metastasis.

19 Nov 2019

Rutgers Cancer Institute researchers awarded $2.3 million in American Cancer Society grants

More than $2.3 million in Research Scholar Grants from the American Cancer Society have been awarded to three Rutgers Cancer Institute of New Jersey researchers to examine cell metabolism and tumor formation in forms of breast cancer, lung cancer and leukemia.

19 Nov 2019

Researchers identify “mutational footprint” caused by chemotherapy that leads to side effects

Researchers have characterized the "mutational footprint" that results from chemotherapy and leads to long-term side effects.

18 Nov 2019

Research breakthrough may lead to new therapeutic targets for cancers

Computational modeling is the use of computers to simulate and study the behavior of complex systems. Computational approaches are widely adopted in the bioimedical sciences and can be used to sift through large volumes of complex data to extract recurrent patterns that may point to a disease's causes and effects.

15 Nov 2019

Study: 15,000 cases of hypophosphatasia potentially undetected in Spanish population

Hypophosphatasia (HPP) is a rare and serious hereditary disease that is potentially life-threatening and is caused by one or more mutations in the gene coding for alkaline phosphatase (ALPL). It is frequently misdiagnosed.

15 Nov 2019

Virginia Tech professor wins $1.85 million NIH grant for sepsis research

One drop of blood contains 5,000 neutrophils, the most abundant type of white blood cell that is deployed by the human immune system. Throughout the entire body, a human has 25 billion of these foot soldiers that are relentlessly patrolling to fight invading pathogens.

12 Nov 2019

Collaborative study shows sex-specific processes in schizophrenia and bipolar disorder

Recent studies have found a high genetic similarity of the psychiatric diseases schizophrenia and bipolar disorder, whose disease-specific changes in brain cells show an overlap of more than 70 percent.

12 Nov 2019

New recommendations aim to improve outcomes of Parkinson's disease patients

Since the discovery that the gut microbiome may play a role in the development of Parkinson's disease (PD), this fresh scientific approach has produced varying results. In this review published in the Journal of Parkinson's Disease scientists compare results of current research and provide recommendations to increase the comparability and utility of these studies with a view towards improving patient outcomes.

11 Nov 2019

Study shows how glucocorticoid hormones control sugar and fat levels over the course of 24 hours

For the first time, a study led by researchers at Helmholtz Zentrum München and the German Center for Diabetes Research shows how glucocorticoid hormones, such as cortisol, control sugar and fat levels differently during day and night, feeding and fasting, rest and activity, over the course of 24 hours.

10 Nov 2019

San Diego-based Predictive Science releases first forecast for influenza season

San Diego-based Predictive Science, Inc. this week released their first forecast for the 2019-2020 influenza season, which typically runs from November through March.

4 Nov 2019

New, open-source database improves genomics research collaboration

Sharing datasets that reveal the function of genomic variants in health and disease has become easier, with the launch of a new, open-source database developed by Australian and North American researchers.

3 Nov 2019

Discovery of human cell signaling systems using bioinformatics

There are many and various receptors on the surface of each human cell, which bind to specific molecules called ligands, to set off signals that modulate cell activity accordingly. These pathways are exploited by therapeutic drugs. In fact, one in three drugs makes use of receptors belonging to a single very large family – the GPCR (G protein receptor coupled receptor) family.

1 Nov 2019

Study identifies a kinase as potential target to treat heart failure

An unexplored kinase in heart muscle cells may be a good target to treat heart failure, a disease that is only incrementally delayed by existing therapies.

31 Oct 2019

New software helps assess interoperability and reusability of biomedical digital research objects

Mount Sinai investigators, together with an international consortium of colleagues, have developed a new toolbox to allow scientists to assess how easily the digital objects they generate as a result of their research projects can be used by other research teams.

31 Oct 2019

Polygenic scoring system shows promise to predict depression risk and resilience under stress

Depression doesn't come from one gene, one life event, or one personality trait. That's what makes it so hard to predict, prevent or treat effectively.

29 Oct 2019

New method can indicate prognosis of aggressive breast cancer

Aggressive forms of breast cancer often manipulate the immune response in their favor. This manipulation is revealed in humans by the same immunological "signature" as in mice. This is shown by a study carried out by scientists from the University of Bonn together with Dutch colleagues.

29 Oct 2019

Researchers develop new genomic analysis method for identifying Yersinia strains

The Yersinia genus covers a vast range of bacteria that are distinguished by criteria such as whether or not they are able to cause disease (their pathogenicity).

29 Oct 2019

Bioinformatics News and Research

Further Reading

Inhibition of a protease could improve the treatment of IBD, study shows

Study finds autism-related genetic mutations in aging brains of Alzheimer's patients

Wound healing events in mucous tissues could guard against AIDS

New technology may offer alternative means of profiling tissues

Rutgers Cancer Institute researchers awarded $2.3 million in American Cancer Society grants

Researchers identify “mutational footprint” caused by chemotherapy that leads to side effects

Research breakthrough may lead to new therapeutic targets for cancers

Study: 15,000 cases of hypophosphatasia potentially undetected in Spanish population

Virginia Tech professor wins $1.85 million NIH grant for sepsis research

Collaborative study shows sex-specific processes in schizophrenia and bipolar disorder

New recommendations aim to improve outcomes of Parkinson's disease patients

Study shows how glucocorticoid hormones control sugar and fat levels over the course of 24 hours

San Diego-based Predictive Science releases first forecast for influenza season

New, open-source database improves genomics research collaboration

Discovery of human cell signaling systems using bioinformatics

Study identifies a kinase as potential target to treat heart failure

New software helps assess interoperability and reusability of biomedical digital research objects

Polygenic scoring system shows promise to predict depression risk and resilience under stress

New method can indicate prognosis of aggressive breast cancer

Researchers develop new genomic analysis method for identifying Yersinia strains

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