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Researchers reveal mechanisms that connect Mfn2 protein to endoplasmic reticulum stress

Each cell in an organism has a sensor that measures the health of its "internal" environment. This "alarm" is found in the endoplasmic reticulum, which is able to sense cellular stress and trigger either rescue responses or the death of the cell.

18 Sep 2013

UCLA receives multimillion-dollar gift to provide patients with innovative home health program

A multimillion-dollar gift has allowed the UCLA Division of Digestive Diseases to provide patients with an innovative home health program; supported new, minimally invasive treatment procedures; and funded state-of-the-art gastroenterology research.

10 Sep 2013

Cellular Biomedicine Group reports interim results of Phase I/IIa clinical trial for Knee Osteoarthritis

Cellular Biomedicine Group, Inc. today announced the interim results of its Phase I/IIa clinical trial for human adipose-derived mesenchymal precursor cell (haMPC) therapy for Knee Osteoarthritis, which tests the safety and efficacy of intra-articular injections of autologous (patient's own) haMPCs in order to reduce inflammation and repair damaged joint cartilage.

6 Sep 2013

Southampton researchers investigates influence of mechanical forces on cellular, molecular processes

University of Southampton researchers are at the forefront of research into mechanobiology, an emerging field of science combining biology and engineering, which investigates the influence of mechanical forces on cellular and molecular processes.

5 Sep 2013

Researchers patent biomaterial that generates artificial bones from umbilical cord stem cells

Scientists in Granada, Spain, have patented a new biomaterial that facilitates generating bone tissue-artificial bones in other words-from umbilical cord stem cells . The material, consisting of an activated carbon cloth support for cells that differentiate giving rise to a product that can promote bone growth, has recently been presented at a press conference at the Biomedical Research Centre, Granada.

19 Jul 2013

Chemical compound from ocean microbe offers potential treatments for anthrax

A team led by William Fenical at Scripps Institution of Oceanography at UC San Diego has discovered a new chemical compound from an ocean microbe in a preliminary research finding that could one day set the stage for new treatments for anthrax and other ailments such as methicillin-resistant Staphylococcus aureus (MRSA).

18 Jul 2013

One step closer to understanding how to control cancer cells without harming healthy ones

The nasty side effects of radiation and chemotherapy are well known: fatigue, hair loss and nausea, to name a few. Cancer treatment can seem as harsh as the disease because it can't differentiate healthy cells from cancerous cells, killing both.

17 Jul 2013

Study on assisted reproduction published in Reproductive BioMedicine Online

Elsevier, a world-leading provider of scientific, technical and medical information products and services, today announced the publication of a recent retrospective study in Reproductive BioMedicine Online to better understand treatment considerations and outcomes for same-sex male couples and single men when using assisted reproduction treatment.

4 Jul 2013

Researchers say hCNT1 protein may affect cancer cells physiology, apart from transport function

The protein hCNT1, which plays a major role in nucleoside transport, may have other biological functions that may affect cancer cells physiology, apart from their transport function. This is the main conclusion of the new scientific work published on the journal Cell Death and Disease.

26 Jun 2013

New breakthrough in chemical nanoengineering may help develop light-regulated therapeutic molecules

The scientific cooperation between chemists, biotechnologists and physicists from various Catalan institutes, headed by Pau Gorostiza, from the Institute for Bioengineering of Catalonia (IBEC), and Ernest Giralt, from the Institute for Research in Biomedicine (IRB Barcelona), has led to a breakthrough that will favor the development of light-regulated therapeutic molecules.

19 Jun 2013

FGF21 endocrine hormone which reduces glucose levels also protects against cardiac diseases in mice

A research group has found that FGF21, an endocrine factor which reduces glucose levels, protects against cardiac diseases in mice. The research, published online on the journal Nature Communications, was led by Francesc Villarroya, professor from the Department of Biochemistry and Molecular Biology of the UB and Director of the Institute of Biomedicine of the University of Barcelona (IBUB), affiliated centre with the campus of international excellence BKC.

18 Jun 2013

Bioapplications of nanoparticles: an interview with Dr Catherine Berry, University of Glasgow

These particles are all classed as inorganic particles, which can all be utilised in biomedical applications. They differ in terms of their inherent material and size dependent physiochemical properties, for example, their optical and magnetic properties.

18 Jun 2013

Researchers find master regulator of EMT and metastasis

The predominant cause of death in cancer patients is metastasis, the formation of secondary tumors in other organs like the brain, liver, and lungs. Cancer cells detach from the original primary tumor and reach a single cell or group of cells in another organ. The cells of the body normally remain in place through adhering to an extracellular substance. However, cancer cells learn how to release themselves from these bonds and invade surrounding tissues, blood, and the lymphatic system.

11 Jun 2013

Study shows PDH enzyme plays a major role in regulation of oncogene-induced cellular senescence

An article published on the journal Nature describes the major role that Pyruvate dehydrogenase (PDH) —an enzyme of cellular energy metabolism— plays in the regulation of the cellular senescence induced by the oncogene BRAF, which usually appears mutated in melanoma and other cancers.

22 May 2013

FAPESP funds $680 million to support 17 RIDCs

The Brazilian funding agency for scientific and technological research S-o Paulo Research Foundation, FAPESP, based in the state of S-o Paulo, announced an investment estimated in US$ 680 million to support 17 Research, Innovation and Dissemination Centers for a period of up to eleven years, subject to continuation reviews on years 2, 4 and 7.

22 May 2013

Major breakthrough in IVF treatment

Elsevier, a world-leading provider of scientific, technical and medical information products and services, today announced the publication of a recent study in Reproductive BioMedicine Online on 5-day old human blastocysts showing that those with an abnormal chromosomal composition can be identified by the rate at which they have developed to blastocysts, thereby classifying the risk of genetic abnormality without a biopsy.

20 May 2013

34% of all adverts for antidepressants are misleading by industry's self-regulation system

The new feature of the antidepressant drugs of the 1990s was that they had milder side-effects than their predecessors. Combined with aggressive marketing, this meant that annual sales in Sweden increased from just under EUR 18 million to over EUR 100 million in the space of just a few years.

6 May 2013

Metabolic risk factors in overweight children linked with mild artery wall stiffness

Metabolic disorders, such as excess abdominal fat, raised blood pressure, higher levels of insulin, glucose and triglycerides and lower levels of the beneficial HDL cholesterol can be found in children as young as 6 to 8 years of age, according to a study carried out at the University of Eastern Finland.

26 Apr 2013

OHSU, Intel team up to develop technologies to make personalized genomic analysis faster

Oregon Health & Science University and Intel Corp. are teaming up to develop next-generation computing technologies that advance the field of personalized medicine by dramatically increasing the speed, precision and cost-effectiveness of analyzing a patient's individual genetic profile.

23 Apr 2013

Study provides medical chemists with tools to design safer drugs, predict their side effects

Yellow vision, pseudo-pulmonary obstruction, involuntary body movements, respiratory paralysis. These are some of the 1,600 known side effects (SEs) produced by drugs.

22 Apr 2013