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New retinal prosthesis restores vision in blind mice and detects near-infrared light in macaques

A new prosthesis for the retina weaved with nanowires partially restored vision in blind mice and allowed detection of near-infrared light in macaques, according to a new study.

6 Jun 2025

Genetic study reveals why some children respond better to myopia lenses

Myopia, or nearsightedness, has reached epidemic levels worldwide, particularly in East and Southeast Asia.

5 Jun 2025

Study challenges taurine as a biomarker of aging

Research in animals and humans has suggested low levels of taurine may be a driver for aging, which has led to discussions about whether taurine is an aging biomarker.

5 Jun 2025

Compact diagnostic platform enables rapid COVID-19 antibody testing from fingertip blood

Researchers from the Shenzhen Institutes of Advanced Technology (SIAT), Chinese Academy of Sciences, along with multiple collaborators, have developed a compact diagnostic platform that can evaluate antibody protection against COVID-19 using only a single microliter of fingertip blood.

5 Jun 2025

Genetic mutation identified as key factor in immunotherapy resistance for melanoma

Tests in 1,225 patients with the most deadly form of skin cancer reveal for the first time a genetic trait among most of those who did not respond to the latest cancer treatments, known as immune checkpoint inhibitors.

5 Jun 2025

New data shows zigakibart sustains proteinuria remission and kidney function in IgA nephropathy

New 100-week data from the ongoing Phase 1/2 study of zigakibart, an investigational anti-APRIL monoclonal antibody, reinforce its potential as a disease-modifying treatment for IgA nephropathy (IgAN).

5 Jun 2025

P2Y12 inhibitors linked to lower rates of cardiovascular events compared to aspirin

Giving a P2Y12 inhibitor anti-clotting drug to patients with coronary artery disease is associated with lower rates of cardiovascular death, heart attack and stroke compared with traditional aspirin, with no increased risk of major bleeding, finds a study published by The BMJ today.

5 Jun 2025

Gene editing can trigger inflammatory, senescence-like responses in blood stem cells

Scientists at the San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), Milan, have found that gene editing using CRISPR-Cas9 in combination with AAV6 vectors can trigger inflammatory and senescence-like responses in blood stem cells, compromising their long-term ability to regenerate the blood system.

5 Jun 2025

AI-designed drug shows early promise for lung fibrosis patients in clinical trial

Researchers report that rentosertib, an AI-discovered TNIK inhibitor, showed promising safety and potential to improve lung function in patients with idiopathic pulmonary fibrosis in a 12-week phase 2a clinical trial. The highest dose group demonstrated a trend toward increased forced vital capacity, especially among patients not receiving standard antifibrotic therapy, supporting further clinical investigation.

4 Jun 2025

New technique improve success rates in treating strokes and other clot-related diseases

When treating an ischemic stroke – where a clot is blocking the flow of oxygen to the brain – every minute counts.

4 Jun 2025

AI and clinicians compared in handling complex medical cases

A University of Maine study compared how well artificial intelligence models and human clinicians handled complex or sensitive medical cases.

4 Jun 2025

New marker identifies the functional maturity and heterogeneity of stem cell–derived islet organoids

Over 500 million people worldwide suffer from diabetes-a disease that contributes to major complications such as stroke, kidney failure, cancer, and Alzheimer's disease.

4 Jun 2025

Key proteins and pathways drive the success of CAR-T cell therapy

A study conducted by researchers at the Center for Cell-Based Therapy (CTC) highlights key proteins and signaling pathways involved in the efficacy of immunotherapy based on CAR-T cells (lymphocytes modified in the laboratory to fight cancer).

4 Jun 2025

Navigating the dual role of B cells in tumor immunity

B lymphocytes exhibit dual roles in tumorigenesis, acting as both allies and adversaries in the tumor microenvironment (TME).

3 Jun 2025

Early camizestrant therapy keeps advanced breast cancer in check

Switching to camizestrant, a next-generation oral SERD, significantly prolongs progression-free survival and maintains quality of life in patients with ESR1-mutated, hormone receptor-positive advanced breast cancer. The proactive, biomarker-guided approach allows earlier intervention and may redefine standard care.

3 Jun 2025

Real world data confirms effectiveness of nirsevimab in young infants with bronchiolitis

A single dose of the long-acting antibody nirsevimab developed to prevent respiratory syncytial virus infections (The drug has been approved at the European level to protect infants in their first season of exposure to the virus) to infants can halve hospitalizations for bronchiolitis.

3 Jun 2025

PfSPZ-LARC2 malaria vaccine advances to new age groups after successful safety review

Physician-scientists at Groupe de Recherche Action en Santé (GRAS) in Burkina Faso have successfully completed initial safety evaluations in 30 adult Burkinabés as the first phase of a clinical trial of Sanaria PfSPZ-LARC2 Vaccine, which is designed to prevent infection with Plasmodium falciparum malaria.

3 Jun 2025

Myeloid cells shape tumor microenvironments and influence cancer progression

Recent advances in cancer research have underscored the critical role of myeloid cells in shaping tumor microenvironments (TME), influencing tumor progression, immune evasion, and therapeutic resistance.

3 Jun 2025

Transforming IBS treatment through psychedelic medicine

In a comprehensive Genomic Press Interview published today, Dr. Erin E. Mauney reveals how her pioneering research brings psychedelic medicine into gastroenterology for the first time, potentially transforming treatment for millions suffering from intractable irritable bowel syndrome (IBS).

3 Jun 2025

Asthma drug once hoped to treat alcohol use disorder fails to meet expectations in UCLA trial

A drug that once showed promise as a treatment for alcohol use disorder did not work as expected, a new UCLA clinical trial found.

3 Jun 2025

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Efficacy News and Research

New retinal prosthesis restores vision in blind mice and detects near-infrared light in macaques

Genetic study reveals why some children respond better to myopia lenses

Study challenges taurine as a biomarker of aging

Compact diagnostic platform enables rapid COVID-19 antibody testing from fingertip blood

Genetic mutation identified as key factor in immunotherapy resistance for melanoma

New data shows zigakibart sustains proteinuria remission and kidney function in IgA nephropathy

P2Y12 inhibitors linked to lower rates of cardiovascular events compared to aspirin

Gene editing can trigger inflammatory, senescence-like responses in blood stem cells

AI-designed drug shows early promise for lung fibrosis patients in clinical trial

New technique improve success rates in treating strokes and other clot-related diseases

AI and clinicians compared in handling complex medical cases

New marker identifies the functional maturity and heterogeneity of stem cell–derived islet organoids

Key proteins and pathways drive the success of CAR-T cell therapy

Navigating the dual role of B cells in tumor immunity

Early camizestrant therapy keeps advanced breast cancer in check

Real world data confirms effectiveness of nirsevimab in young infants with bronchiolitis

PfSPZ-LARC2 malaria vaccine advances to new age groups after successful safety review

Myeloid cells shape tumor microenvironments and influence cancer progression

Transforming IBS treatment through psychedelic medicine

Asthma drug once hoped to treat alcohol use disorder fails to meet expectations in UCLA trial

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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