Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Discovery of toxic and protective short RNAs associated with Alzheimer's disease and superior memory capacity

Researchers explored how Death Induced by Survival gene Elimination through the analysis of RNA-induced silencing complex-bound short RNAs in Alzheimer's disease models influences neuronal survival and correlates with neurotoxicity in AD.

22 Jan 2024

Ludwig scientists deconstruct the blood supply of brain metastases

A Ludwig Cancer Research study has generated a granular portrait of how the cellular and molecular components of the blood vessels that feed brain metastases of melanoma and lung and breast cancers differ from those of healthy brain tissue, illuminating how they help shape the internal environment of tumors to support cancer growth and immune evasion.

19 Jan 2024

Mathematical modeling demonstrates efficacy of combinational drug therapy for breast cancer treatment

Researchers use a mathematical model to assess the efficacy of a new combinational therapy of AZD9496 and palbociclib for breast cancer treatment.

18 Jan 2024

Decoding blood cancer secrets to optimize CAR T therapy

Chimeric antigen receptor T-cell therapy, or CAR T, has dramatically improved the treatment of certain blood cancers. Initially approved for patients who had failed multiple lines of therapy, clinical trials have shown CAR T can be used as an earlier treatment option.

17 Jan 2024

New study shows how brain glucose affects fungal disease treatment

Metabolite-drug-fungal interactions in the fungal meningitis pathogen Cryptococcus neoformans.

16 Jan 2024

Immune dysregulation in long COVID patients uncovered in new study

Sstudy reveals significant immune changes in long COVID patients, including altered T cell responses and systemic inflammation, using advanced 'omics' and serological assays.

14 Jan 2024

RBM5 identified as key regulator of HOXA9 in acute myeloid leukemia

The protein HOXA9 is overexpressed in most acute myeloid leukemia (AML) cases and is associated with poor patient outcomes.

12 Jan 2024

Paternal sperm microRNAs also play a role in offspring health

A recent study has reported that changes in mice sperm microRNAs brought about by aging may affect the growth and development of offspring.

12 Jan 2024

Uncovering the role of ER-mitochondria connections in muscle atrophy

The loss of muscle mass, or muscle atrophy, is a relatively common condition in today's aging and increasingly sedentary societies.

12 Jan 2024

Scientists develop noninvasive way to monitor gene expression dynamics in the brain

Researchers introduced a non-invasive, sensitive method for monitoring gene expression in the brain using engineered reporters called released markers of activity, which can exit the brain into the blood for easy detection.

12 Jan 2024

Long-term expansion and self-organization of human fetal brain organoids

Researchers establish fetal brain organoids as a versatile platform for brain cancer modeling.

12 Jan 2024

Big data analysis paves way for personalized ovarian cancer treatment

A recent study led by Hidenori Machino at the RIKEN Center for Advanced Intelligence Project (AIP) and the National Cancer Center Research Institute in Japan used a big data multi-omics analysis to examine changes in gene expression as cells from human fallopian tubes become cancerous.

11 Jan 2024