Respiratory News and Research

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Lifesaving innovation for COVID-19 will increase the already existing racial inequalities

As is the case with most fatal diseases, coronavirus disease (COVID-19) is already taking a disproportionate toll on black Americans and other disadvantaged minorities.

20 May 2020

Universal testing of asymptomatic pregnant women may not be necessary, study suggests

A study conducted by investigators at Cedars-Sinai suggests that universal testing of asymptomatic pregnant women in labor may not be necessary at every hospital.

20 May 2020

MIT researchers describe new methods for accelerating drug approvals during pandemics

In response to the COVID-19 pandemic, researchers from the Massachusetts Institute of Technology have published a pair of studies in a COVID-19 special issue of the Harvard Data Science Review, freely available via open access, describing new methods for accelerating drug approvals during pandemics and for providing more accurate measures of the probabilities of success for clinical trials of vaccines and other anti-infective therapies.

20 May 2020

FDA approves IND application by Octapharma USA for severe COVID-19 patients

The U.S. Food and Drug Administration (FDA) has approved the investigational new drug (IND) application submitted by Octapharma USA for a phase three clinical trial on the efficacy and safety of Octagam 10% [Immune Globulin Intravenous (Human)] therapy in COVID-19 patients with severe disease progression.

20 May 2020

Study focuses on COVID-19 patients with inflammatory rheumatic diseases

The ongoing COVID-19 pandemic has caused nearly five million cases and over 327,000 deaths worldwide. The signs and symptoms of this disease are varied, although there are typical features which assist diagnosis.

20 May 2020

Children not likely to be main drivers of COVID-19 pandemic, review suggests

It is highly likely that children can transmit the new coronavirus, which causes COVID-19, but several factors suggest that children are unlikely to be the main drivers of the pandemic.

20 May 2020

Main receptors used by SARS-CoV-2 for cell entry are absent in the human placenta

Although severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is unlikely to infect human placenta through the canonical cell entry mediators, Wayne State University researchers showed that other interacting proteins may still play an important role during the viral infection. The study is currently available on the preprint server bioRxiv.

20 May 2020

Henry Ford Health System first to enroll a pediatric patient in HEROS study

Henry Ford Health System is first in the country to enroll a patient in the Human Epidemiology and Response to SARS-CoV-2 study, which aims to help determine the rate of SARS-CoV-2, the virus that causes COVID-19, among U.S. children and their family members, and what percentage of children infected with SARS-CoV-2 develop symptoms of the disease.

20 May 2020

Study shows engineered SARS-CoV-2 spike protein may be utilized for vaccine development

In a new study available on the preprint server bioRxiv, researchers demonstrate how the conformation of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein (S-protein) can be controlled with the rational construct design, providing a framework for S-protein structure engineering in vaccine/drug development.

20 May 2020

African American communities more burdened by COVID-19, say researchers

A new study conducted by researchers at Florida International University, Miami, has found that communities in the United States with a high density of African Americans are disproportionately burdened with the adverse outcomes of coronavirus disease 2019 (COVID-19).

20 May 2020

Certain corticosteroid could improve severe COVID-19, say researchers

Researchers at Wayne State University and Henry Ford Health System in Michigan have conducted a study indicating that the corticosteroid methylprednisolone could improve outcomes among patients with severe coronavirus disease 2019 (COVID-19).

20 May 2020

Dana-Farber launches clinical test of blood cancer drug in COVID-19 patients

Scientists at Dana-Farber Cancer Institute have launched a clinical test of a blood cancer drug in patients infected with the COVID-19 virus. T

20 May 2020

Immunologists propose possible molecular mechanism for the deadly respiratory syndrome

Research into how the SARS-CoV-2 virus induces death is suggesting potential treatments for its most destructive complications.

20 May 2020

Researchers measure the health effects of indoor ultrafine particulates

Leipzig/Berlin. Residents of large German cities have it above all in their own hands how high the concentrations of ultrafine dust are in their homes.

20 May 2020

CDC plans nationwide antibody study to determine the magnitude of the coronavirus pandemic

The U.S. Centers for Disease Control and Prevention (CDC) plans to launch a nationwide study to track how the novel coronavirus is spreading across the country.

20 May 2020

Moderna’s coronavirus vaccine candidate shows promise in phase I trial

Moderna, who partnered with the National Institutes of Health, announced that its candidate vaccine appeared to be safe when administered to eight healthy volunteers. The vaccine also stimulated an immune response to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes the coronavirus disease (COVID-19).

20 May 2020

Countries that develop a coronavirus vaccine may not share it, health expert warns

The pandemic has sparked a worldwide race to develop a vaccine against the novel coronavirus. But a health expert has warned that the world might face a risk of "vaccine nationalism," wherein countries who will produce a coronavirus vaccine will not share it with others.

20 May 2020

Respiratory News and Research

Lifesaving innovation for COVID-19 will increase the already existing racial inequalities

Universal testing of asymptomatic pregnant women may not be necessary, study suggests

MIT researchers describe new methods for accelerating drug approvals during pandemics

FDA approves IND application by Octapharma USA for severe COVID-19 patients

Study focuses on COVID-19 patients with inflammatory rheumatic diseases

Children not likely to be main drivers of COVID-19 pandemic, review suggests

Main receptors used by SARS-CoV-2 for cell entry are absent in the human placenta

Henry Ford Health System first to enroll a pediatric patient in HEROS study

Study shows engineered SARS-CoV-2 spike protein may be utilized for vaccine development

African American communities more burdened by COVID-19, say researchers

Certain corticosteroid could improve severe COVID-19, say researchers

Dana-Farber launches clinical test of blood cancer drug in COVID-19 patients

Immunologists propose possible molecular mechanism for the deadly respiratory syndrome

Researchers measure the health effects of indoor ultrafine particulates

CDC plans nationwide antibody study to determine the magnitude of the coronavirus pandemic

Moderna’s coronavirus vaccine candidate shows promise in phase I trial

Countries that develop a coronavirus vaccine may not share it, health expert warns

Report describes clinical characteristics and outcomes of children hospitalized with COVID-19

Researchers describe new methods to speed up drug approvals during pandemics

Australian COVID-19 prevention trial begins for frontline and allied healthcare workers

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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