Metastasis News and Research

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Metastasis is the spread of cancer from one part of the body to another. A tumor formed by cells that have spread is called a “metastatic tumor” or a “metastasis.” The metastatic tumor contains cells that are like those in the original (primary) tumor. The plural form of metastasis is metastases

Engineered stem cells offer new treatment for metastatic bone cancer

Engineered stem cells could help treat metastatic cancers in bone without killing normal surrounding bone.

9 Jul 2019

New class of cancer-killing agents shows promise in destroying cancer stem cells

Scientists at The University of Toledo investigating improvements to a commonly used chemotherapy drug have discovered an entirely new class of cancer-killing agents that show promise in eradicating cancer stem cells.

9 Jul 2019

Researchers discover novel cancer-promoting molecular mechanism

A novel cancer-promoting molecular mechanism has been discovered by Pierluigi Scalia, M.D., Ph.D., with his co-workers at the Sbarro Institute for Cancer Research and Molecular Medicine, Division of Biology, Temple University, the Department of Medical Biotechnologies at University of Siena, Italy and the Italian non-profit research organization ISOPROG, in collaboration with the Center of Biocomputational Sciences, part of the College of Science and Technology in Philadelphia.

8 Jul 2019

HER2-positive breast cancer may be treated with imprinted nanospheres

A particularly aggressive, metastasizing form of cancer, HER2-positive breast cancer, may be treated with nanoscopic particles “imprinted” with specific binding sites for the receptor molecule HER2.

4 Jul 2019

Non-pathogenic bacteria engineered as Trojan Horse to treat tumors from within

The emerging field of synthetic biology-designing new biological components and systems-is revolutionizing medicine.

4 Jul 2019

New discovery may help predict recurrence of pancreatic neuroendocrine tumors

Researchers have discovered two distinct subtypes of pancreatic neuroendocrine tumors – known as pNETs – that have dramatically different risks of recurrence following surgical treatment [or surgery].

4 Jul 2019

New resistance mechanism that prevent formation of blood vessels

Researchers at IDIBELL-ICO describe a new resistance mechanism to therapies that prevent the formation of blood vessels

3 Jul 2019

3D breast tumor models may improve drug discovery and testing

Dr. Hossein Tavana, an associate professor of biomedical engineering at The University of Akron, has received a grant of $1.13 million from the prestigious National Cancer Institute to further develop 3D tumor models of triple-negative breast cancer -- which may improve drug testing and lead to the discovery of new, more effective anticancer drugs.

2 Jul 2019

Discovery by NETRF-funded researchers may help predict recurrence of pNETs

ARX and PDX1 levels can be measured using immunohistochemistry, a test that stains tumor tissue and is routine in clinical laboratories.

2 Jul 2019

Protein linked to malignant melanoma

Almost 300,000 people worldwide develop malignant melanoma each year. The disease is the most serious form of skin cancer and the number of cases reported annually is increasing, making skin cancer one of Sweden's most common forms of cancer.

28 Jun 2019

Promising new approaches in the fight against brain metastasis

Research is currently pursuing several highly promising approaches in the fight against cancers that give rise to metastases in the brain.

28 Jun 2019

Scientists reveal mechanism of tumor metastasis and tumor-suppressive role of UDP-glucose

Scientists from Dalian Institute of Chemical Physics and Shanghai Institute of Biochemistry and Cell Biology of the Chinese Academy of Sciences revealed that UDP-glucose accelerates SNAI1 mRNA decay and impairs lung cancer metastasis.

27 Jun 2019

A metabolic intermediate in the uronic acid pathway impairs lung cancer metastasis

In a study published online in Nature on June 26, research teams led by Dr. YANG Weiwei at the Institute of Biochemistry and Cell Biology of the Chinese Academy of Sciences and Dr. LI Guohui from the Dalian Institute of Chemical Physics of CAS reported a new function of uridine diphosphate glucose (UDP-glucose), a metabolic intermediate in the uronic acid pathway: It impairs lung cancer metastasis by accelerating SNAI1 mRNA decay.

27 Jun 2019

New class of radiopharmaceuticals offer fresh perspective on cancer imaging, theranostics

Research presented at the 2019 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging describes a new class of radiopharmaceuticals, named radiohybrids, that offer a fresh perspective on cancer imaging and radioligand therapy.

26 Jun 2019

UAB scientists identify new target for drug intervention in Alzheimer's disease

Scientists at the University of Alabama at Birmingham have identified an enzyme in the brain that may be an intriguing target for interventions against Alzheimer's disease and other dementias.

26 Jun 2019

Atomwise and Enamine launch 10 billion compound virtual drug screening initiative

Atomwise, Inc. today announced the launch of a 10 billion compound AI-powered virtual drug screening initiative, the 10-to-the-10 program, in collaboration with Enamine Ltd., the world’s largest chemical supplier.

25 Jun 2019

Researchers explore new immune checkpoint for head and neck cancer

A checkpoint may delay travelers but it can help give cancer free rein by suppressing the natural immune response that should destroy it, researchers say.

25 Jun 2019

More insights into transport protein used by cancer cells

Certain cancer cells depend on exporting the metabolite lactate, which accumulates during the generation on energy. Lactate plays an important role in many biochemical and cellular processes.

21 Jun 2019

UT Dallas adds MILabs Hybrid OI/CT system to its innovative medical imaging solutions

The Department of Bioengineering at the UT Dallas is adding a MILabs Hybrid OI/CT system to its innovative medical imaging solutions.

20 Jun 2019

Novel microfluidic device captures and isolates circulating tumor cell clusters

Cancer touches nearly everyone in one way or another, and regrettably, it will claim another 600,000 lives in the U.S. in 2019, according to the American Cancer Society. Researchers from San Diego State University, TumorGen MDx Inc., and Sanford Burnham Prebys Medical Discovery Institute set out to explore a seemingly basic question: What is it about cancer that kills?

19 Jun 2019