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Functional magnetic resonance imaging aids study of brain development

Functional magnetic resonance imaging (fMRI) is a powerful noninvasive tool for studying brain activity in both humans and experimental animals.

3 Dec 2007

DNA methylation shown to promote development of colon tumors

Damaged or defective genes have long been known to be the cause of some cancers.

2 Dec 2007

Bacteria cheat on their mates for own good

Pursuing our own short term interests by cheating on the rest of the population is not the preserve of the human race.

29 Nov 2007

Sirtris Pharmaceuticals unveils promising, novel SIRT1 activators for treating diseases of aging

Sirtris Pharmaceuticals has announced that findings in the journal Nature demonstrate that Sirtris has developed novel drug candidates that offer a promising, new approach to treating diseases of aging, including Type 2 Diabetes, by targeting SIRT1, a gene that controls the aging process.

29 Nov 2007

Genetic differences point to ethnic and racial disparities in colorectal cancer risk

Risk of developing colorectal cancer is known to differ across ethnic and racial groups, and now an analysis of 26 studies, involving over 25,000 participants shows that some of these disparities might be explained by distinct patterns of genetic inheritance.

29 Nov 2007

Deadly variations of superbug now spreading beyond the hospital

Experts in Britain say virulent bugs such as MRSA (methicillin resistant Staphylococcus aureus) are now spreading beyond hospitals and into the wider community and may put lives at risk.

27 Nov 2007

Discovery of gene responsible for statin-induced muscle pain

Statins, the popular class of drugs used to lower cholesterol, are among the most commonly prescribed medications in developed countries.

27 Nov 2007

RNA polymerase III mutation disrupts organ growth

The cellular mechanism that turns DNA into all of the thousands of proteins that make up a human body is itself both intricate and interesting.

27 Nov 2007

Insulin regulates the secretion of the antiaging hormome Klotho

Dr. Carmela Abraham, a professor of biochemistry and medicine at Boston University School of Medicine (BUSM), reports this week in the Proceedings of the National Academy of Sciences new findings on Klotho, an anti-aging gene that is associated with life span extension in rodents and humans.

27 Nov 2007

Superbug strains have spread to nursing homes and into the community

Hospital superbugs that can break down antibiotics are so widespread throughout Europe that doctors increasingly have to use the few remaining drugs that they reserve for emergencies.

27 Nov 2007

BioMarin files investigational NDA for PEG-PAL for the treatment of phenylketonuria

BioMarin Pharmaceutical Inc. has announced that it has filed an investigational new drug application (IND) with the U.S. Food and Drug Administration (FDA) for PEG-PAL (Poly Ethylene Glycol-Phenylalanine Ammonia Lyase), formerly known as Phenylase, for the treatment of phenylketonuria (PKU).

27 Nov 2007

Scientists examine eons-old water for microorganisms

Researchers from the University of Delaware and the University of California at Riverside have thawed ice estimated to be at least a million years old from above Lake Vostok, an ancient lake that lies hidden more than two miles beneath the frozen surface of Antarctica.

27 Nov 2007

Study of Mexican Americans shows that polymorphisms of the CYP2E1 gene enhance susceptibility to alcoholism

Mexican Americans make up 66 percent of the U.S. Hispanic population and, when compared to other ethnic groups, show high rates of heavy drinking and alcohol-related problems.

27 Nov 2007

There is a new twist on the question of how biological clocks work

In recent years, scientists have discovered that biological clocks help organize a dizzying array of biochemical processes in the body. Despite a number of hypotheses, exactly how the microscopic pacemakers in every cell in the body exert such a widespread influence has remained a mystery.

21 Nov 2007

Research shows how embryonic cells may regulate levels of retinoic acid

Human embryos that get too much or too little retinoic acid, a derivative of Vitamin A, can develop into babies with birth defects.

21 Nov 2007

Chlamydia pneumoniae involved in both heart disease and infertility

Outside the laboratory, Anthony Azenabor is outgoing and talkative, an extrovert who laughs heartily at his own jokes.

21 Nov 2007

Regulation of the retinoic acid gradient in zebrafish embryos

Human embryos that get too much or too little retinoic acid, a derivative of Vitamin A, can develop into babies with birth defects.

21 Nov 2007

Protein in mice known as RGS13 suppresses allergic reactions

A protein in mice known as RGS13 suppresses allergic reactions, including the severe, life-threatening allergic reaction known as anaphylaxis, according to scientists at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH).

20 Nov 2007

New technique enables the detection of biomolecules' dynamic reactions in a single living cell

By taking advantage of the signature frequency by which organic and inorganic molecules absorb light, the team of researchers, led by Luke Lee, professor of bioengineering and director of UC Berkeley's Biomolecular Nanotechnology Center, can determine in real time whether specific enzymes are activated or particular genes are expressed, all with unprecedented resolution within a single living cell.

19 Nov 2007

Sitting may increase risk of disease

Most people spend most of their day sitting with relatively idle muscles. Health professionals advise that at least 30 minutes of activity at least 5 days a week will counteract health concerns, such as cardiovascular disease, diabetes and obesity that may result from inactivity.

19 Nov 2007