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A protein discovery could pave way to better treatments for obesity

A USC-led international team of scientists has found the precise shape of a key player in human metabolism, which could lead the way to better treatments for obesity and other metabolic disease.

23 Apr 2020

Is the confidence in hydroxychloroquine for the management of COVID-19 justified?

A new review paper published in the preprint open-access journal medRxiv in April 2020 reports that there is not enough evidence to justify the widespread use of the drug hydroxychloroquine (HCQ) in the treatment or prophylaxis of the current COVID-19 illness.

23 Apr 2020

Fewer kids enroll in pediatric oncology clinical trials, study shows

Historically, pediatric cancer patients have been much more likely than adult cancer patients to enroll in clinical trials as part of their treatment.

23 Apr 2020

RAS inhibitors and COVID-19 severity in hypertensive patients

A new study published in the journal JAMA Cardiology in April 2020 reports that patients with hypertension who are taking medications called ACE inhibitors (ACEI) or ARBs are not at higher risk for death or more severe illness with COVID-19. This conclusion supports current guidelines for the treatment of hypertension during this pandemic.

23 Apr 2020

New clinical trial to test two drugs for prophylactic treatment of COVID-19 contact persons

With the stepwise easing of measures in Switzerland, it is pivotal to monitor for any new COVID-19 outbreaks and to contain them in a timely and effective manner.

23 Apr 2020

A faster and easier treatment option to prevent blindness in preterm infants

Babies born prematurely who require treatment to prevent blindness from retinopathy of prematurity (ROP) could be treated with a dose of Avastin (bevacizumab) that is a fraction of the dose commonly used for ROP currently.

23 Apr 2020

Breakthrough discovery in HIV research opens path to new, better therapies

New research on the human immunodeficiency virus (HIV) structure has revealed a promising novel drug target for treating it.

23 Apr 2020

Coronavirus crisis opens access to online opioid addiction treatment

Opioid addiction isn't taking a break during the coronavirus pandemic.

23 Apr 2020

Ablexis, AlivaMab Discovery Services, and Berkeley Lights Collaborate to Identify a Diverse Panel of Anti-SARS-CoV-2 Human Antibodies

Ablexis, LLC, ADS, and Berkeley Lights, Inc. today announced the generation and recovery of sequences against the S1 spike protein of the SARS-CoV-2 virus.

From Bruker Cellular Analysis 23 Apr 2020

Study: Somatostatin treatment in cerebral cortex may improve visual processing, cognitive behaviors

Researchers have confirmed that neuropeptide somatostatin can improve cognitive function in the brain. A research group of Professor Seung-Hee Lee from the Department of Biological Sciences at KAIST found that the application of neuropeptide somatostatin improves visual processing and cognitive behaviors by reducing excitatory inputs to parvalbumin-positive interneurons in the cortex.

23 Apr 2020

Researchers develop new blood test for Alzheimer's disease

A new blood test for Alzheimer's disease has been developed under the leadership of researchers at the University of Gothenburg, Sweden. The method is based on measuring a specific variant of tau protein in ordinary blood samples, which makes the test relatively simple and cheap to perform.

23 Apr 2020

Researchers show how drug particles spread around crime labs

When two scientists from the National Institute of Standards and Technology (NIST) brought black lights and glow powder into the Maryland State Police crime lab, they weren't setting up a laser tag studio or nightclub.

23 Apr 2020

Combinations of PAC and WFA are highly synergistic against proliferation of non-small cell lung cancer

Oncotarget Volume 11 Issue 16 showed that the sensitivity of H1299 and A549 cells to concomitant treatment with PAC and WFA was greater than that of either PAC or WFA alone.

23 Apr 2020

Researchers demonstrate how TB bacteria import vitamin B12 molecules to grow

Researchers from Russia, the Netherlands, Sweden, and the U.S. have revealed the structure of the protein responsible for vitamin B12 import into the cells of the bacterium that causes tuberculosis. The research findings were published in Nature.

23 Apr 2020

Chinese scientists develop two novel compounds that inhibit SARS-CoV-2 main protease

A team of Chinese scientists has recently developed two novel compounds that inhibit the SARS-CoV-2 main protease (Mpro) and one of them is a good drug candidate for further clinical studies.

23 Apr 2020

Series of rare side effects underscores the need to track targeted anti-cancer drugs

Tejas Patil, MD, is a medical oncologist. Lisa Ferrigno, MD, MPH, FACS, is a trauma surgeon. Working with lung cancer patients at University of Colorado Cancer Center, they both, independently, noticed something strange:

23 Apr 2020

COST Action creates “Task Force” of researchers to contribute to Covid-19 research

STRATAGEM COST Action (New diagnostic and therapeutic tools against multidrug resistant tumors) has created a "Task Force" of researchers contributing to Covid-19 research.

23 Apr 2020

Meis1 protein plays key role in stopping cell division in the heart

UT Southwestern Medical Center scientists have discovered a protein that works with others during development to put the brakes on cell division in the heart, they report today in Nature.

23 Apr 2020

AMPK activation by anti-diabetes drug promotes survival of dormant breast cancer cells

Most breast cancers utilize the female hormone estrogen to grow, so drug-induced estrogen deprivation is used as a treatment in many patients. However, cancer will recur in one-third of these patients.

22 Apr 2020

Scientists identify cells likely targeted by novel coronavirus

Researchers at MIT; the Ragon Institute of MGH, MIT, and Harvard; and the Broad Institute of MIT and Harvard; along with colleagues from around the world have identified specific types of cells that appear to be targets of the coronavirus that is causing the Covid-19 pandemic.

22 Apr 2020

Drugs News and Research

A protein discovery could pave way to better treatments for obesity

Is the confidence in hydroxychloroquine for the management of COVID-19 justified?

Fewer kids enroll in pediatric oncology clinical trials, study shows

RAS inhibitors and COVID-19 severity in hypertensive patients

New clinical trial to test two drugs for prophylactic treatment of COVID-19 contact persons

A faster and easier treatment option to prevent blindness in preterm infants

Breakthrough discovery in HIV research opens path to new, better therapies

Coronavirus crisis opens access to online opioid addiction treatment

Ablexis, AlivaMab Discovery Services, and Berkeley Lights Collaborate to Identify a Diverse Panel of Anti-SARS-CoV-2 Human Antibodies

Study: Somatostatin treatment in cerebral cortex may improve visual processing, cognitive behaviors

Researchers develop new blood test for Alzheimer's disease

Researchers show how drug particles spread around crime labs

Combinations of PAC and WFA are highly synergistic against proliferation of non-small cell lung cancer

Researchers demonstrate how TB bacteria import vitamin B12 molecules to grow

Chinese scientists develop two novel compounds that inhibit SARS-CoV-2 main protease

Series of rare side effects underscores the need to track targeted anti-cancer drugs

COST Action creates “Task Force” of researchers to contribute to Covid-19 research

Meis1 protein plays key role in stopping cell division in the heart

AMPK activation by anti-diabetes drug promotes survival of dormant breast cancer cells

Scientists identify cells likely targeted by novel coronavirus

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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