Antibody News and Research

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An antibody is a blood protein that is produced in response to and counteracts an antigen. Antibodies are produced in response to disease and help the body fight against the particular disease. In this way, antibodies help the body develop an immunity to disease.

Daily fetal heart rate monitoring recommended for pregnant women with high anti-SSA/Ro antibodies

Physicians who care for pregnant women have long sought to identify which of their patients would most likely benefit from monitoring of their fetus's heart rate to catch early signs of their unborn child developing heart problems tied to the mother's immune system.

7 Nov 2023

MD Anderson and Jazz Pharmaceuticals collaborate to investigate the potential of zanidatamab in HER2-expressing cancers

The University of Texas MD Anderson Cancer Center and Jazz Pharmaceuticals plc today announced a five-year strategic research collaboration agreement to evaluate zanidatamab, Jazz's investigational HER2-targeted bispecific antibody, in multiple HER2-expressing cancers.

7 Nov 2023

New drug shows promise in blocking pancreatic cancer spread

While the overall cancer death rate has been steadily declining in the U.S. since the 1990s, death rates due to pancreatic cancer are increasing.

7 Nov 2023

New nasal vaccine for COVID-19 shows promise in animal studies

A team of University of Maryland researchers developed a nasal spray vaccine that delivers the SARS-CoV-2 spike protein into cells of the airway in mice and hamsters, triggering an immune response that significantly reduced infection and spread of COVID-19.

6 Nov 2023

Researchers identify a 'Threshold of Immunity' to SARS-CoV-2

How much immunity do we need against COVID-19? New international research led by scientists in Ireland and published in Nature Communications, has identified a 'Threshold of Immunity' to SARS-CoV-2.

6 Nov 2023

Researchers pioneer a novel treatment for the most common autoimmune encephalitis

Researchers at DZNE and Charité - Universitätsmedizin Berlin have pioneered a novel treatment for the most common autoimmune encephalitis.

3 Nov 2023

Bridging Chemistry and Biology: The Art of Designing Novel Therapeutics

In this interview, we delve into the journey and research of Sona Krajcovicova, exploring how diverse interests led to a passionate pursuit of chemistry, innovative approaches to drug development, and a commitment to making a meaningful impact on the world of therapeutics.

From ELRIG (UK) Ltd. 2 Nov 2023

New treatment breakthrough: Pyrotinib combo demonstrates remarkable efficacy for HER2 positive metastatic breast cancer

The safety and efficacy of treating human epidermal growth factor receptor 2 (HER2)-positive metastatic breast cancer with pyrotinib.

2 Nov 2023

How one gene shakes up our understanding of male infertility

The study investigates the role of the ACTL7B gene in sperm formation using genetically modified mice and finds that deficiencies in this gene lead to failed spermatogenesis and structural sperm abnormalities. Given the gene's similarity in humans, the findings suggest ACTL7B could serve as a potential biomarker for male infertility.

31 Oct 2023

How next-gen sequencing is changing antibody drug discovery

New study outlines how next-generation sequencing (NGS) and machine-learning methods can revolutionize antibody discovery, particularly against SARS-CoV-2. The research demonstrates that NGS provides greater epitopic and paratopic diversity, enabling more effective identification and prioritization of therapeutic antibodies.

31 Oct 2023

Trastuzumab deruxtecan offers added benefit for patients with HER2-low breast cancer

The antibody-drug conjugate trastuzumab deruxtecan is approved for various therapeutic indications. Since March 2023, it can also be used as monotherapy for the treatment of adults with unresectable or metastatic HER2-low breast cancer who have received prior chemotherapy at this disease stage or developed disease recurrence early after adjuvant chemotherapy.

31 Oct 2023

New classification criteria for antiphospholipid syndrome

APS is a systemic autoimmune disease associated with persistent antiphospholipid antibodies (aPL). It can cause thrombosis and pregnancy complications as well as non-thrombotic manifestations such as cardiac valve disease.

30 Oct 2023

Study unveils new approach to more precise, long-lasting, and less toxic cancer treatment

For too long, cancer treatment has been a double-edged sword – the very treatments designed to kill cancer cells often wrought havoc on healthy ones too.

30 Oct 2023

New antibody may offer effective drug treatment for breast cancer

An enzyme that may help some breast cancers spread can be stopped with an antibody created in the lab of Cold Spring Harbor Laboratory Professor Nicholas Tonks.

30 Oct 2023

New omicron sublineages surge, but Pfizer-BioNTech bivalent booster retains effectiveness

The efficacy of the bivalent Pfizer-BioNTech COVID-19 messenger ribonucleic acid (mRNA) vaccine BNT162b2 BA.4/5.

30 Oct 2023

Diabetic patients with COVID-19: low antibody levels linked to worse outcomes

The role of anti-SARS-CoV-2 antibody levels on COVID-19 outcomes in patients with T2D.

30 Oct 2023

Redefining the battle against Alzheimer's with tau-focused treatments

Researchers explore the potential of tau-targeting therapies in treating Alzheimer's disease, focusing on immunotherapies and strategies to improve their efficacy. The study dives into the complex biology of tau proteins, their modifications, and how they can be targeted to halt the progression of Alzheimer's.

29 Oct 2023

MHRA grants conditional marketing authorization for AbbVie's Tepkinly to treat aggressive blood cancer

AbbVie today announced that the UK Medicines and Healthcare products Regulatory Agency has granted conditional Marketing Authorisation for Tepkinly® (epcoritamab) as a monotherapy for the treatment of adults with relapsed or refractory (R/R) diffuse large B-cell lymphoma (DLBCL), after two or more systemic therapies.

28 Oct 2023

New treatment combination shows promise for metastatic colorectal cancer patients with rare genetic mutation

An international Phase 3 clinical trial found that metastatic colorectal cancer patients with a rare genetic tumor mutation called KRAS G12C experienced superior progression-free survival rates compared to standard of care when offered a combination treatment of KRAS inhibitor sotorasib and monoclonal antibody panitumumab.

27 Oct 2023

A new era of vaccines leaves old questions about prices unanswered

The world is entering a new era of vaccines. Following the success of covid-19 mRNA shots, scientists have a far greater capacity to tailor shots to a virus's structure, putting a host of new vaccines on the horizon.

27 Oct 2023

Antibody News and Research

Further Reading

Daily fetal heart rate monitoring recommended for pregnant women with high anti-SSA/Ro antibodies

MD Anderson and Jazz Pharmaceuticals collaborate to investigate the potential of zanidatamab in HER2-expressing cancers

New drug shows promise in blocking pancreatic cancer spread

New nasal vaccine for COVID-19 shows promise in animal studies

Researchers identify a 'Threshold of Immunity' to SARS-CoV-2

Researchers pioneer a novel treatment for the most common autoimmune encephalitis

Bridging Chemistry and Biology: The Art of Designing Novel Therapeutics

New treatment breakthrough: Pyrotinib combo demonstrates remarkable efficacy for HER2 positive metastatic breast cancer

How one gene shakes up our understanding of male infertility

How next-gen sequencing is changing antibody drug discovery

Trastuzumab deruxtecan offers added benefit for patients with HER2-low breast cancer

New classification criteria for antiphospholipid syndrome

Study unveils new approach to more precise, long-lasting, and less toxic cancer treatment

New antibody may offer effective drug treatment for breast cancer

New omicron sublineages surge, but Pfizer-BioNTech bivalent booster retains effectiveness

Diabetic patients with COVID-19: low antibody levels linked to worse outcomes

Redefining the battle against Alzheimer's with tau-focused treatments

MHRA grants conditional marketing authorization for AbbVie's Tepkinly to treat aggressive blood cancer

New treatment combination shows promise for metastatic colorectal cancer patients with rare genetic mutation

A new era of vaccines leaves old questions about prices unanswered

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