Central Nervous System News and Research

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Researchers develop new tools to assess care provided for patients with brain metastasis

Ambitious efforts at UVA Cancer Center to improve care delivered to patients with cancer that has spread to the brain have yielded important insights and tools that can benefit other hospitals, a new publication reports.

7 Oct 2020

New clinical report on brain changes in deceased COVID-19 patients

German researchers published a report on a series of cases on post mortem findings of COVID-19 patients who succumbed to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection along with neurological complications. Their study titled “Neuropathology of patients with COVID-19 in Germany: a post-mortem case series” is published in the latest issue of The Lancet Neurology.

6 Oct 2020

IL-21 protein is a major part of immune response to chronic infections in the central nervous system

Researchers at Penn State College of Medicine now better understand the role of a protein, interleukin-21 (IL-21), in the immune system response to infections in the nervous system.

6 Oct 2020

New tools to enhance care for brain metastases

5 Oct 2020

Researchers identify a promising method to treat multiple sclerosis

Seema Tiwari-Woodruff, a professor of biomedical sciences in the School of Medicine at the University of California, Riverside, and her colleagues have received a grant of $373,000 from the National Multiple Sclerosis Society for a project in which her lab will select the five best candidate compounds to speed up nerve impulses, a promising new avenue to treat multiple sclerosis.

1 Oct 2020

Scientists discover bacteria linked to post-infectious hydrocephalus in infants

Scientists at the Center for Infection and Immunity at Columbia University Mailman School of Public Health have discovered bacteria linked to post-infectious hydrocephalus (PIH), the most common cause of pediatric hydrocephalus worldwide.

30 Sep 2020

New porous material enables the degradation of compounds analogous to nerve agents

A team from the Institute of Molecular Science (ICMol) of the University of Valencia has succeeded in synthesizing a new porous material that enables and guides the degradation of compounds analogous to nerve agents used in chemical warfare.

30 Sep 2020

Researchers identify a new method to produce miniaturized antibodies

Researchers at the University of Bath in the UK and biopharma company UCB have found a way to produce miniaturized antibodies, opening the way for a potential new class of treatments for diseases.

30 Sep 2020

NCCN publishes new clinical practice guidelines for pediatric Hodgkin lymphoma

The National Comprehensive Cancer Network today announced the publication of new NCCN Clinical Practice Guidelines in Oncology for Pediatric Hodgkin Lymphoma. Hodgkin lymphoma is one of the most curable forms of pediatric cancer, with long-term survival rates of 90% or higher.

28 Sep 2020

Researchers elucidate the impact of genetic mutations in cocaine addiction

Cocaine addiction is a chronic disorder with a high rate of relapse for which no effective treatment is currently available.

26 Sep 2020

Study identifies hiding place where tumor cells shelter from chemotherapy in childhood leukemia

The stroma of the choroid plexus is one of the locations within the central nervous system (CNS) that serves as a shelter for tumor cells, allowing them to elude chemotherapy and potentially cause subsequent relapses in childhood acute lymphoblastic leukaemia, according to research led by the Complutense University of Madrid.

25 Sep 2020

Dextran sulphate-induced tau assemblies cause tau propagation in non-transgenic mice

Accumulation of assembled tau protein in the central nervous system is characteristic of Alzheimer's disease and several other neurodegenerative diseases, called tauopathies.

23 Sep 2020

'Silent' wave of neurological consequences may be on its way due to COVID-19

Is the world prepared a wave of neurological consequences that may be on its way as a result of COVID-19? This question is at the forefront of research underway at the Florey Institute of Neuroscience and Mental Health.

23 Sep 2020

Targeted treatment for systemic lupus erythematosus

A team of researchers from Charité - Universitätsmedizin Berlin and the Deutsches Rheuma-Forschungszentrum Berlin, a Leibniz Institute, have successfully treated two patients with the autoimmune disease systemic lupus erythematosus.

22 Sep 2020

Intra-CREATE grants awarded to support research on personalized medicine and cell therapy

Researchers from Critical Analytics for Manufacturing Personalized-Medicine, an interdisciplinary research group at Singapore-MIT Alliance for Research and Technology, MIT's research enterprise in Singapore, have been awarded Intra-CREATE grants from the National Research Foundation Singapore to help support research on retinal biometrics for glaucoma progression and neural cell implantation therapy for spinal cord injuries.

22 Sep 2020

Scientists investigate active plasma metabolite of remdesivir in SARS-CoV-2 mouse model

Using mouse models, scientists have investigated the active plasma metabolite of remdesivir, GS-441 524, and hydroxychloroquine as possible drug candidates in COVID-19. The research shows GS-441 524 could be an effective therapeutic drug against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), while at the same time discounting hydroxychloroquine as a reliable anti-viral.

20 Sep 2020

Animal data supports efficacy of baricitinib vs SARS-COV-2

The high burden of disease caused by the COVID-19 pandemic has led to much research on effective ways to mitigate the health, social, and economic impact of the spread of the infection. A recent study published on the preprint server bioRxiv* in September 2020 reports on the characteristics of the drug baricitinib when used as monotherapy to treat severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

17 Sep 2020

Michigan sees increasing EEE cases

In the United States, the Michigan Department of Health and Human Services (MDHHS) urge people to stay indoors, especially after dusk. Health officials have confirmed 22 horse cases of Eastern Equine Encephalitis (EEE), and one suspected human case.

17 Sep 2020

Smart drug delivery system may help treat spinal cord injuries, neurological disorders

A Rutgers-led team has created a smart drug delivery system that reduces inflammation in damaged nervous tissues and may help treat spinal cord injuries and other neurological disorders.

17 Sep 2020

Study: Significant proportion of older dental patients inappropriately prescribed opioids

A new study by researchers at the University of Illinois Chicago and the University of Pittsburgh suggests that a significant proportion of older patients receiving opioids at dental visits also use psychotropic medications -- a potentially harmful combination.

16 Sep 2020

Central Nervous System News and Research

Researchers develop new tools to assess care provided for patients with brain metastasis

New clinical report on brain changes in deceased COVID-19 patients

IL-21 protein is a major part of immune response to chronic infections in the central nervous system

New tools to enhance care for brain metastases

Researchers identify a promising method to treat multiple sclerosis

Scientists discover bacteria linked to post-infectious hydrocephalus in infants

New porous material enables the degradation of compounds analogous to nerve agents

Researchers identify a new method to produce miniaturized antibodies

NCCN publishes new clinical practice guidelines for pediatric Hodgkin lymphoma

Researchers elucidate the impact of genetic mutations in cocaine addiction

Study identifies hiding place where tumor cells shelter from chemotherapy in childhood leukemia

Dextran sulphate-induced tau assemblies cause tau propagation in non-transgenic mice

'Silent' wave of neurological consequences may be on its way due to COVID-19

Targeted treatment for systemic lupus erythematosus

Intra-CREATE grants awarded to support research on personalized medicine and cell therapy

Scientists investigate active plasma metabolite of remdesivir in SARS-CoV-2 mouse model

Animal data supports efficacy of baricitinib vs SARS-COV-2

Michigan sees increasing EEE cases

Smart drug delivery system may help treat spinal cord injuries, neurological disorders

Study: Significant proportion of older dental patients inappropriately prescribed opioids

Event guide: The 7th CNS Drug Delivery Summit eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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