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Study: HIV-positive women respond well to vaccine against human papillomavirus

HIV-positive women respond well to a vaccine against the human papillomavirus (HPV), even when their immune system is struggling, according to newly published results of an international clinical trial.

17 Apr 2014

IVF prevents multiple births in patients undergoing fertility treatments

While fertility treatments have helped many people become parents, they commonly result in multiple births, increasing the risk of prematurity, and leading to lifelong complications.

17 Apr 2014

Baxter reports topline results from BAX 111 Phase 3 trial for treatment of von Willebrand disease

Baxter International Inc. today announced topline results from a Phase 3 clinical trial evaluating the safety, efficacy and pharmacokinetics (PK) of BAX 111. BAX 111 is a recombinant von Willebrand factor (rVWF) under investigation for the treatment of bleeding episodes in patients with von Willebrand disease, the most common type of inherited bleeding disorder.

From Baxter International Inc. 16 Apr 2014

NICE recommends FIRMAGON for treating advanced hormone-dependent prostate cancer in adults with spinal metastases

The National Institute for Health and Care Excellence (NICE) today issued its Final Appraisal Determination (FAD) recommending FIRMAGON (degarelix) as an option for treating advanced hormone-dependent prostate cancer, only in adults with spinal metastases who present with signs or symptoms of spinal cord compression.

16 Apr 2014

Community efforts boost people for HIV testing and reduce new infections

Communities in Africa and Thailand that worked together on HIV-prevention efforts saw not only a rise in HIV screening but a drop in new infections, according to a new study in the peer-reviewed journal The Lancet Global Health.

16 Apr 2014

Two biomarkers could help predict ASD, other developmental delays in young children

Researchers, including a team from Children's National Health System, have identified head circumference and head tilting reflex as two reliable biomarkers in the identification of autism spectrum disorders (ASD) in children that are between 9 and 12 months of age.

16 Apr 2014

Pitt CVR and Sanofi Pasteur join forces to help assess effectiveness of dengue vaccine

The University of Pittsburgh Center for Vaccine Research (CVR) and Sanofi Pasteur, the vaccines division of Sanofi, have entered a scientific collaboration to help assess the effectiveness of a dengue vaccine once introduced for immunization programs.

16 Apr 2014

Akebia completes enrollment in ongoing 200-patient Phase 2b study of AKB-6548

Akebia Therapeutics, Inc., a biopharmaceutical company focused on the development of novel proprietary therapeutics based on hypoxia-inducible factor (HIF) biology and the commercialization of these products for patients with kidney disease, today announced it has completed enrollment in its ongoing 200-patient Phase 2b study of AKB-6548 for the treatment of anemia associated with chronic kidney disease (CKD) in patients who are not dependent on dialysis.

16 Apr 2014

Effects of PectaSol-C modified citrus pectin in prostate cancer patients to be studied in phase III trial

A phase III clinical trial conducted at the Meir Medical Center in Kfar-Saba, Israel is now recruiting participants to study the effects of dietary supplement PectaSol-C modified citrus pectin (MCP) in controlling prostate specific antigen (PSA) levels in prostate cancer patients.

15 Apr 2014

New data focuses on different approaches to improve diagnosis and treatment of HCC

Epidemiological, genetic and clinical data presented today at the International Liver CongressTM 2014 are collectively focussed on different approaches designed to improve the diagnosis, staging and treatment of hepatocellular carcinoma (HCC).

15 Apr 2014

Researchers identify new Chinese herbal medicine that inhibits hepatitis C virus activity

Data from a late-breaking abstract presented at the International Liver CongressTM 2014 identifies a new compound, SBEL1, that has the ability to inhibit hepatitis C virus (HCV) activity in cells at several points in the virus' lifecycle.

15 Apr 2014

Obeticholic acid meets primary composite endpoint in Phase III study

Results from an international Phase III study presented today at the International Liver CongressTM 2014 have shown obeticholic acid (OCA) given to patients suffering from Primary Biliary Cirrhosis (PBC) who previously had an inadequate response to, or have been unable to tolerate ursodeoxycholic acid (UDCA), produced meaningful biochemical and clinical improvements. UDCA is the only therapy currently approved to treat PBC.

15 Apr 2014

Vivolux receives FDA clearance to proceed with phase I/II clinical trial of VLX600

Vivolux AB, a drug discovery company specialized in cancer treatment, announced today that the FDA has granted clearance to proceed with VLX600 into the clinical phase I/II. VLX600 is one of the company's promising projects, and which was recently published in the journal Nature Communications.

15 Apr 2014

Study: Immunization program in UK has reduced HPV infections in young women

Each year around 2,000-2,500 women are diagnosed with cervical cancer in England, the most common cancer in women under 35. Infection with high-risk human papillomavirus (HR HPV) types 16 and 18 is responsible for around 70-80% of cervical cancers.

15 Apr 2014

Low-cost empowerment program for adolescent girls sharply curtails sexual harassment

A low-cost empowerment program for adolescent girls in Kenyan slums sharply curtails rape and sexual harassment of these girls, who live in an environment where women have low status and are frequently attacked, a large new study shows.

15 Apr 2014

Amrubicin regimen inferior to irinotecan for extensive SCLC

Irinotecan plus cisplatin remains the gold standard for Japanese patients with extensive small-cell lung cancer, say researchers, after amrubicin plus cisplatin failed to improve survival in their randomised phase III trial.

11 Apr 2014

Tau Therapeutics presents data of T-type calcium channel inhibitors in treatment of pancreatic cancer

Tau Therapeutics LLC announced today that its academic collaborator, University of Virginia Professor Todd Bauer, MD, presented data at the 105th Annual Meeting of the American Association for Cancer Research (AACR), the premier cancer research event held in San Diego, California from April 5-9.

11 Apr 2014

New Dartmouth study offers roadmap for better risk adjustment in Medicare

The methodology Medicare uses to adjust the billions of dollars it pays health plans and hospitals to account for how sick their patients are is flawed and should be replaced, according to a new study by Dartmouth investigators published in the journal BMJ that weighed the performance of Medicare's methodology against alternatives.

11 Apr 2014

Scientists report successful nose reconstruction surgery using cartilage grown in laboratory

Scientists at the University of Basel report first ever successful nose reconstruction surgery using cartilage grown in the laboratory. Cartilage cells were extracted from the patient's nasal septum, multiplied and expanded onto a collagen membrane.

11 Apr 2014

Compressyn Band selected as finalist in Medical Design Excellence Awards for Implant and Tissue-Replacement Products Category

Dallen Medical, Inc. is pleased to announce that the Compressyn™ Band has been selected as a finalist in the Implant and Tissue-Replacement Products Category of the 17th Annual Medical Design Excellence Awards competition.

10 Apr 2014

Efficacy News and Research

Study: HIV-positive women respond well to vaccine against human papillomavirus

IVF prevents multiple births in patients undergoing fertility treatments

Baxter reports topline results from BAX 111 Phase 3 trial for treatment of von Willebrand disease

NICE recommends FIRMAGON for treating advanced hormone-dependent prostate cancer in adults with spinal metastases

Community efforts boost people for HIV testing and reduce new infections

Two biomarkers could help predict ASD, other developmental delays in young children

Pitt CVR and Sanofi Pasteur join forces to help assess effectiveness of dengue vaccine

Akebia completes enrollment in ongoing 200-patient Phase 2b study of AKB-6548

Effects of PectaSol-C modified citrus pectin in prostate cancer patients to be studied in phase III trial

New data focuses on different approaches to improve diagnosis and treatment of HCC

Researchers identify new Chinese herbal medicine that inhibits hepatitis C virus activity

Obeticholic acid meets primary composite endpoint in Phase III study

Vivolux receives FDA clearance to proceed with phase I/II clinical trial of VLX600

Study: Immunization program in UK has reduced HPV infections in young women

Low-cost empowerment program for adolescent girls sharply curtails sexual harassment

Amrubicin regimen inferior to irinotecan for extensive SCLC

Tau Therapeutics presents data of T-type calcium channel inhibitors in treatment of pancreatic cancer

New Dartmouth study offers roadmap for better risk adjustment in Medicare

Scientists report successful nose reconstruction surgery using cartilage grown in laboratory

Compressyn Band selected as finalist in Medical Design Excellence Awards for Implant and Tissue-Replacement Products Category

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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