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A recombinant platform for flavivirus vaccines and diagnostics using chimeras

A new technology to produce safer ‘hybrid’ viruses at high volumes for use in vaccines and diagnostics for mosquito-borne diseases has been developed at The University of Queensland.

11 Dec 2019

Study provides most detailed classification of acute myeloid leukemia, myelodysplastic syndrome

Results from a study conducted by St. Jude Children's Research Hospital and the Munich Leukemia Laboratory were presented today as a late-breaking abstract at the American Society of Hematology annual meeting. The study integrates genomic and transcriptomic sequencing to provide the most detailed classification of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) to date.

10 Dec 2019

Researchers discover a widespread method used by phages to hide from bacterial defenses

University of Otago researchers have discovered how viruses that specifically kill bacteria can outwit bacteria by hiding from their defenses, findings which are important for the development of new antimicrobials based on viruses and provide a significant advance in biological knowledge.

10 Dec 2019

Small, thin metal mesh loaded with T cells shrinks tumors in ovarian cancer models

New findings published Dec. 9 in Nature Biomedical Engineering from scientists at Fred Hutchinson Cancer Research Center show for the first time that a piece of small, thin metal mesh loaded with cancer-fighting immune cells shrinks tumors in preclinical models of ovarian cancer.

9 Dec 2019

Some phages employ new strategy to avoid becoming the next casualty of DNA-dicing enzymes

Bacteria and the viruses that infect them are engaged in a molecular arms race as ancient as life itself. Evolution has equipped bacteria with an arsenal of immune enzymes, including CRISPR-Cas systems, that target and destroy viral DNA. But bacteria-killing viruses, also known as phages, have devised their own tools to help them outmaneuver even the most formidable of these bacterial defenses.

9 Dec 2019

Novel nanopipette pH biosensor could help with cancer diagnosis and treatment

Nanopipettes with zwitterionic membranes may offer improved monitoring of changes in pH surrounding living cells, which can indicate traits of invasive cancer cells and their response to treatment, report researchers at Kanazawa University in Nature Communications.

6 Dec 2019

The Olympus scanR High-Content Screening Station Rapidly Acquires Quantitative Data from Cell-Based Assays

Olympus announces the US launch of the scanR high-content screening (HCS) station, a cell imaging solution that utilizes artificial intelligence (AI) to enable next-generation biological research.

From Evident Corporation - Life Sciences 6 Dec 2019

Thin hair tends to be stronger than thick hair, study shows

Despite being four times thicker than human hair, elephant hair is only half as strong--that's just one finding from researchers studying the hair strength of many different mammals.

6 Dec 2019

Researchers successfully develop imaging technology of conjunctival goblet cells

Goblet cells are epithelial cells that produce mucins and disperse tears which help the surface of eyes maintain the wet environment. Goblet cells are closely related to autoimmune disease including dry eyes and chemical burns. Therefore, it is very important to examine the status of goblet cells to better understand and diagnose ocular disease.

5 Dec 2019

A woman has developed rare form of lung metal-scarring from vaping

A woman who had been vaping cannabis oil has been diagnosed with rare type of lung scarring usually only seen in metalworkers.

5 Dec 2019

Why some sperm swim in circles – it’s a protein defect

A new study published in the journal PNAS shows that some sperm cannot swim straight because they lack a protein called VSP. This motility defect seriously impacts the rates of successful fertilization. In addition, VSP is also found to regulate the amount of calcium that enters the flagellum, the whiplike organelle that propels the sperm towards the waiting ovum or egg. This important discovery may help treat infertility more effectively.

3 Dec 2019

Researchers identify new drug target for treating neurological disorders

Understanding how the brain processes sweet, bitter and umami tastes may one day help researchers design more effective drugs for neurological disorders.

3 Dec 2019

New approach helps study the decision-making process in the brain

Without hardly noticing, we make countless decisions: to turn left or right on the bus? To wait or to accelerate? To look or to ignore? In the run-up to these decisions the brain evaluates sensory information and only then does it generate a behavior.

2 Dec 2019

75-year old blood-stained microscope slide reveals historical spread of malaria

DNA from 75-year old eradicated European malaria parasites uncovers the historical spread of one of the two most common forms of the disease, Plasmodium vivax, from Europe to the Americas during the colonial period, finds a new study co-led by UCL.

2 Dec 2019

Gene discovery in fruit flies could provide clues to counteract mitochondrial diseases

Scientists have identified a protein in fruit flies that can be targeted to reverse the effects of disease-causing mutations in mitochondrial genes. The discovery could provide clues about how to counteract human mitochondrial diseases, for which there is currently no cure.

28 Nov 2019

Dangerous bacteria send out warning signals when attacked by antibiotics

A bacterial infection is not just an unpleasant experience - it can also be a major health problem. Some bacteria develop resistance to otherwise effective treatment with antibiotics.

22 Nov 2019

Novel microscope optimizes illumination to improve diagnosis

Engineers at Duke University have developed a microscope that adapts its lighting angles, colors and patterns while teaching itself the optimal settings needed to complete a given diagnostic task.

20 Nov 2019

Lowering the Barriers to Automated Microscopy

News-Medical Life Sciences spoke to Zaber Technologies at Neuroscience 2019 to find out how they are lowering the barriers of automated microscopy.

From Zaber 19 Nov 2019

Researchers decode molecular structure of cytochrome bd oxidase from E. coli

Both humans and many other creatures need oxygen for survival. In the conversion of nutrients into energy, the oxygen is converted to water, for which the enzyme oxidase is responsible. It represents the last step of the so-called respiratory chain.

14 Nov 2019

Deep neural network could improve cancer care

Improving the detection, diagnosis, and treatment of diseases like cancer will require more detailed, rapid, and agile imaging technology that can show doctors not just what a specific organ looks like, but also what's happening within the cells that make up those tissues.

13 Nov 2019